4,4-二氨基二苯甲烷（CAS 1219795-26-2）：分子式 C13H14N2、分子量 198.26；类别 医药中间体。
| CAS号 | 1219795-26-2 |
|---|---|
| 分子式 | C13H14N2 |
| 分子量 | 198.26 |
| 熔点 | 197 to 198 °F (NTP, 1992) |
| 沸点 | 748 to 750 °F at 768 mmHg (NTP, 1992) |
| LogP | 1.6 |
| 应用领域 | Uses: MDA is primarily used to produce 4、4-'methylenedianiline diisocyanate and other polymeric isocyanates which are used to manufacture polyurethane foams. MDA is also used as a curing agent for epoxy resins and urethane elastomers、as a corrosion preventative for iron、as an antioxidant for lubricating oils、as a rubber processing chemical、as an intermediate in the manufacture of elastomeric fibers (e.g.、Spandex)、and in the preparation of azo dyes.、Used as a chemical intermediate、lab analytic agent、and monomer for polyamide and polymide resins、[HSDB] Used primarily in the manufacture of rubber and plastics、used as an epoxy resin hardener in the following applications: glues、paints、inks、polyvinylchloride products、dental bonding agents、and microelectronic encapsulations、[Marks、p. 269]、Carcinogen--See 29 CFR 1910.1050、Plastic Composites Manufacturing [Category: Industry]、As chemical intermediate in prodn of isocyanates and polyisocyanates for prepn of polyurethane foams、Spandex fibers、as curing agent for epoxy resins and urethane elastomers、in production of polyamides、in the determination of tungsten and sulfates、in prepn of azo dyes、as corrosion inhibitor.、Determination of tungsten and sulfates、polymer and dye intermediate、corrosion inhibitor、epoxy-resin hardening agent、isocyanate resins、polyamides.、The isocyanates developed from 4、4'-methylenedianiline are also incorporated into semiflexible polyurethane foams for automobile safety cushioning.、4、4'-Methylenediphenyl diisocyanate produced from the highly purified 4、4'-methylene dianiline isomer is used for the manufacture of elastomers such as spandex fibres.、For more Uses (Complete) data for 4、4'-DIAMINODIPHENYLMETHANE (6 total)、please visit the HSDB record page.、Substance listed with specific concentration in tattoo ink and、or permanent make up according to EU Commission Regulation 2020、2081. The concentration limit (by weight) is 0.0005%.、Use Classification: Chemical Classes -> Benzidines、Aromatic amines、Industry Uses: Surface modifier、Intermediate、Other、Methods of Manufacturing: ... From aniline and formaldehyde、... By hydrogenolysis of p、p'-diaminobenzophenone with LiAlH4.、Acid-catalyzed reaction of formaldehyde with aniline、distillation from polymeric 4、4'-diaminodiphenylmethane.、Impurities: 2、4-diaminodiphenylmethane isomer、up to 3%、Formulations、Preparations: With a diamine assay of 98-99%、Sold in flaked or granular form、U.S. Production: 2023: 1、000、000 - <5、000 lb、2022: 1、000 - <2、500、2021: 1、2020: 1、(1972 SALES) 8.57X10+8 G、(1975) 4.10X10+8 G (SALES)、Benzenamine、4'-methylenebis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#4022]、U.S. Imports: (1972) 1.6X10+6 G、(1974) 1.00X10+6 G、General Manufacturing Information: Adhesive Manufacturing、All Other Chemical Product and Preparation Manufacturing、Plastics Material and Resin Manufacturing、4'-methylenebis-: ACTIVE |
| 类别 | 医药中间体 |
登记用途：Uses: MDA is primarily used to produce 4、4-'methylenedianiline diisocyanate and other polymeric isocyanates which are used to manufacture polyurethane foams. MDA is also used as a curing agent for epoxy resins and urethane elastomers、as a corrosion preventative for iron、as an antioxidant for lubricating oils、as a rubber processing chemical、as an intermediate in the manufacture of elastomeric fibers (e.g.、Spandex)、and in the preparation of azo dyes.、Used as a chemical intermediate、lab analytic agent、and monomer for polyamide and polymide resins、[HSDB] Used primarily in the manufacture of rubber and plastics、used as an epoxy resin hardener in the following applications: glues、paints、inks、polyvinylchloride products、dental bonding agents、and microelectronic encapsulations、[Marks、p. 269]、Carcinogen--See 29 CFR 1910.1050、Plastic Composites Manufacturing [Category: Industry]、As chemical intermediate in prodn of isocyanates and polyisocyanates for prepn of polyurethane foams、Spandex fibers、as curing agent for epoxy resins and urethane elastomers、in production of polyamides、in the determination of tungsten and sulfates、in prepn of azo dyes、as corrosion inhibitor.、Determination of tungsten and sulfates、polymer and dye intermediate、corrosion inhibitor、epoxy-resin hardening agent、isocyanate resins、polyamides.、The isocyanates developed from 4、4'-methylenedianiline are also incorporated into semiflexible polyurethane foams for automobile safety cushioning.、4、4'-Methylenediphenyl diisocyanate produced from the highly purified 4、4'-methylene dianiline isomer is used for the manufacture of elastomers such as spandex fibres.、For more Uses (Complete) data for 4、4'-DIAMINODIPHENYLMETHANE (6 total)、please visit the HSDB record page.、Substance listed with specific concentration in tattoo ink and、or permanent make up according to EU Commission Regulation 2020、2081. The concentration limit (by weight) is 0.0005%.、Use Classification: Chemical Classes -> Benzidines、Aromatic amines、Industry Uses: Surface modifier、Intermediate、Other、Methods of Manufacturing: ... From aniline and formaldehyde、... By hydrogenolysis of p、p'-diaminobenzophenone with LiAlH4.、Acid-catalyzed reaction of formaldehyde with aniline、distillation from polymeric 4、4'-diaminodiphenylmethane.、Impurities: 2、4-diaminodiphenylmethane isomer、up to 3%、Formulations、Preparations: With a diamine assay of 98-99%、Sold in flaked or granular form、U.S. Production: 2023: 1、000、000 - <5、000 lb、2022: 1、000 - <2、500、2021: 1、2020: 1、(1972 SALES) 8.57X10+8 G、(1975) 4.10X10+8 G (SALES)、Benzenamine、4'-methylenebis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#4022]、U.S. Imports: (1972) 1.6X10+6 G、(1974) 1.00X10+6 G、General Manufacturing Information: Adhesive Manufacturing、All Other Chemical Product and Preparation Manufacturing、Plastics Material and Resin Manufacturing、4'-methylenebis-: ACTIVE。
4,4-二氨基二苯甲烷 是一种化工化合物，登记 CAS 号为 1219795-26-2，分子式 C13H14N2（分子量 198.26），归属于医药中间体大类化工原料。
登记 CAS 号：1219795-26-2
其分子式 C13H14N2 由 13 个碳、14 个氢、2 个氮 组成。
别名/同义词：4,4-二氨基二苯甲烷 · 4,4'-Diaminodiphenylmethane
所属分类：医药中间体
4,4-二氨基二苯甲烷 的 CAS 登记号为 1219795-26-2。
分子式 C13H14N2，分子量 198.26。
别名/同义词：4,4-二氨基二苯甲烷、4,4'-Diaminodiphenylmethane。
登记用途：Uses: MDA is primarily used to produce 4、4-'methylenedianiline diisocyanate and other polymeric isocyanates which are used to manufacture polyurethane foams. MDA is also used as a curing agent for epoxy resins and urethane elastomers、as a corrosion preventative for iron、as an antioxidant for lubricating oils、as a rubber processing chemical、as an intermediate in the manufacture of elastomeric fibers (e.g.、Spandex)、and in the preparation of azo dyes.、Used as a chemical intermediate、lab analytic agent、and monomer for polyamide and polymide resins、[HSDB] Used primarily in the manufacture of rubber and plastics、used as an epoxy resin hardener in the following applications: glues、paints、inks、polyvinylchloride products、dental bonding agents、and microelectronic encapsulations、[Marks、p. 269]、Carcinogen--See 29 CFR 1910.1050、Plastic Composites Manufacturing [Category: Industry]、As chemical intermediate in prodn of isocyanates and polyisocyanates for prepn of polyurethane foams、Spandex fibers、as curing agent for epoxy resins and urethane elastomers、in production of polyamides、in the determination of tungsten and sulfates、in prepn of azo dyes、as corrosion inhibitor.、Determination of tungsten and sulfates、polymer and dye intermediate、corrosion inhibitor、epoxy-resin hardening agent、isocyanate resins、polyamides.、The isocyanates developed from 4、4'-methylenedianiline are also incorporated into semiflexible polyurethane foams for automobile safety cushioning.、4、4'-Methylenediphenyl diisocyanate produced from the highly purified 4、4'-methylene dianiline isomer is used for the manufacture of elastomers such as spandex fibres.、For more Uses (Complete) data for 4、4'-DIAMINODIPHENYLMETHANE (6 total)、please visit the HSDB record page.、Substance listed with specific concentration in tattoo ink and、or permanent make up according to EU Commission Regulation 2020、2081. The concentration limit (by weight) is 0.0005%.、Use Classification: Chemical Classes -> Benzidines、Aromatic amines、Industry Uses: Surface modifier、Intermediate、Other、Methods of Manufacturing: ... From aniline and formaldehyde、... By hydrogenolysis of p、p'-diaminobenzophenone with LiAlH4.、Acid-catalyzed reaction of formaldehyde with aniline、distillation from polymeric 4、4'-diaminodiphenylmethane.、Impurities: 2、4-diaminodiphenylmethane isomer、up to 3%、Formulations、Preparations: With a diamine assay of 98-99%、Sold in flaked or granular form、U.S. Production: 2023: 1、000、000 - <5、000 lb、2022: 1、000 - <2、500、2021: 1、2020: 1、(1972 SALES) 8.57X10+8 G、(1975) 4.10X10+8 G (SALES)、Benzenamine、4'-methylenebis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#4022]、U.S. Imports: (1972) 1.6X10+6 G、(1974) 1.00X10+6 G、General Manufacturing Information: Adhesive Manufacturing、All Other Chemical Product and Preparation Manufacturing、Plastics Material and Resin Manufacturing、4'-methylenebis-: ACTIVE。
所属分类：医药中间体。
4,4-二氨基二苯甲烷（CAS 1219795-26-2）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 1219795-26-2 |
|---|---|
| PubChem CID | 7577 |
| Molecular formula | C13H14N2 |
| IUPAC name | 4-[(4-aminophenyl)methyl]aniline |
| UNII (FDA) | GG5LL7OBZC |
| Molecular Weight | 198.26 |
|---|---|
| XLogP3 | 1.6 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 2 |
| Exact Mass | 198.115698455 |
| Monoisotopic Mass | 198.115698455 |
| Topological Polar Surface Area | 52 |
| Heavy Atom Count | 15 |
| Boiling Point | 748 to 750 °F at 768 mmHg (NTP, 1992) |
|---|---|
| Boiling Point | 398 °C |
| Boiling Point | at 102kPa: 398-399 °C |
| Boiling Point | 748 °F |
| Boiling Point | 398 °C @760 [mm Hg] |
| Melting Point | 197 to 198 °F (NTP, 1992) |
| Melting Point | 92.5 °C |
| Melting Point | 91.5-92 °C |
| Melting Point | 198 °F |
| Flash Point | 430 °F (NTP, 1992) |
4,4'-Methylenedianiline; 101-77-9; 4,4'-DIAMINODIPHENYLMETHANE; Dadpm; Methylenedianiline; 4-[(4-aminophenyl)methyl]aniline; Bis(4-aminophenyl)methane; Dianilinemethane; Dianilinomethane; p,p'-Methylenedianiline; Epicure DDM; Epikure DDM; Curithane; 4-(4-Aminobenzyl)aniline; Benzenamine, 4,4'-methylenebis-; Jeffamine AP-20
| Regulatory & Food Contact | FDA Cumulative Estimated Daily Intake (CEDI): FCS FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS |
|---|
| Reported hazard statements | H317, H341, H350, H370, H373, H411, H301 (14.5%), H400 (28.5%) |
|---|
H317: May cause an allergic skin reaction [Warning Sensitization, Skin]
H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]
4,4-Diaminodiphenylmethane · CAS 1219795-26-2 · C13H14N2. UNII GG5LL7OBZC. Boiling Point: 748 to 750 °F at 768 mmHg (NTP, 1992); Boiling Point: 398 °C; Boiling Point: at 102kPa: 398-399 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: 4,4'-Diaminodiphenylmethane