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4,4'-Diaminodiphenylmethane

CAS 1219795-26-2C13H14N2MW 198.26

4,4'-Diaminodiphenylmethane (CAS 1219795-26-2) — formula C13H14N2, molecular weight 198.26; category chemical.

Product Overview

CAS Number1219795-26-2
Molecular FormulaC13H14N2
Molecular Weight198.26
Melting Point197 to 198 °F (NTP, 1992)
Boiling Point748 to 750 °F at 768 mmHg (NTP, 1992)
LogP1.6
ApplicationsUses: MDA is primarily used to produce 4, 4-'methylenedianiline diisocyanate and other polymeric isocyanates which are used to manufacture polyurethane foams. MDA is also used as a curing agent for epoxy resins and urethane elastomers, as a corrosion preventative for iron, as an antioxidant for lubricating oils, as a rubber processing chemical, as an intermediate in the manufacture of elastomeric fibers (e.g., Spandex), and in the preparation of azo dyes., Used as a chemical intermediate, lab analytic agent, and monomer for polyamide and polymide resins, [HSDB] Used primarily in the manufacture of rubber and plastics, used as an epoxy resin hardener in the following applications: glues, paints, inks, polyvinylchloride products, dental bonding agents, and microelectronic encapsulations, [Marks, p. 269], Carcinogen--See 29 CFR 1910.1050, Plastic Composites Manufacturing [Category: Industry], As chemical intermediate in prodn of isocyanates and polyisocyanates for prepn of polyurethane foams, Spandex fibers, as curing agent for epoxy resins and urethane elastomers, in production of polyamides, in the determination of tungsten and sulfates, in prepn of azo dyes, as corrosion inhibitor., Determination of tungsten and sulfates, polymer and dye intermediate, corrosion inhibitor, epoxy-resin hardening agent, isocyanate resins, polyamides., The isocyanates developed from 4, 4'-methylenedianiline are also incorporated into semiflexible polyurethane foams for automobile safety cushioning., 4, 4'-Methylenediphenyl diisocyanate produced from the highly purified 4, 4'-methylene dianiline isomer is used for the manufacture of elastomers such as spandex fibres., For more Uses (Complete) data for 4, 4'-DIAMINODIPHENYLMETHANE (6 total), please visit the HSDB record page., Substance listed with specific concentration in tattoo ink and, or permanent make up according to EU Commission Regulation 2020, 2081. The concentration limit (by weight) is 0.0005%., Use Classification: Chemical Classes -> Benzidines, Aromatic amines, Industry Uses: Surface modifier, Intermediate, Other, Methods of Manufacturing: ... From aniline and formaldehyde, ... By hydrogenolysis of p, p'-diaminobenzophenone with LiAlH4., Acid-catalyzed reaction of formaldehyde with aniline, distillation from polymeric 4, 4'-diaminodiphenylmethane., Impurities: 2, 4-diaminodiphenylmethane isomer, up to 3%, Formulations, Preparations: With a diamine assay of 98-99%, Sold in flaked or granular form, U.S. Production: 2023: 1, 000, 000 - <5, 000 lb, 2022: 1, 000 - <2, 500, 2021: 1, 2020: 1, (1972 SALES) 8.57X10+8 G, (1975) 4.10X10+8 G (SALES), Benzenamine, 4'-methylenebis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#4022], U.S. Imports: (1972) 1.6X10+6 G, (1974) 1.00X10+6 G, General Manufacturing Information: Adhesive Manufacturing, All Other Chemical Product and Preparation Manufacturing, Plastics Material and Resin Manufacturing, 4'-methylenebis-: ACTIVE
Category医药Intermediates

Applications

Documented applications: Uses: MDA is primarily used to produce 4, 4-'methylenedianiline diisocyanate and other polymeric isocyanates which are used to manufacture polyurethane foams. MDA is also used as a curing agent for epoxy resins and urethane elastomers, as a corrosion preventative for iron, as an antioxidant for lubricating oils, as a rubber processing chemical, as an intermediate in the manufacture of elastomeric fibers (e.g., Spandex), and in the preparation of azo dyes., Used as a chemical intermediate, lab analytic agent, and monomer for polyamide and polymide resins, [HSDB] Used primarily in the manufacture of rubber and plastics, used as an epoxy resin hardener in the following applications: glues, paints, inks, polyvinylchloride products, dental bonding agents, and microelectronic encapsulations, [Marks, p. 269], Carcinogen--See 29 CFR 1910.1050, Plastic Composites Manufacturing [Category: Industry], As chemical intermediate in prodn of isocyanates and polyisocyanates for prepn of polyurethane foams, Spandex fibers, as curing agent for epoxy resins and urethane elastomers, in production of polyamides, in the determination of tungsten and sulfates, in prepn of azo dyes, as corrosion inhibitor., Determination of tungsten and sulfates, polymer and dye intermediate, corrosion inhibitor, epoxy-resin hardening agent, isocyanate resins, polyamides., The isocyanates developed from 4, 4'-methylenedianiline are also incorporated into semiflexible polyurethane foams for automobile safety cushioning., 4, 4'-Methylenediphenyl diisocyanate produced from the highly purified 4, 4'-methylene dianiline isomer is used for the manufacture of elastomers such as spandex fibres., For more Uses (Complete) data for 4, 4'-DIAMINODIPHENYLMETHANE (6 total), please visit the HSDB record page., Substance listed with specific concentration in tattoo ink and, or permanent make up according to EU Commission Regulation 2020, 2081. The concentration limit (by weight) is 0.0005%., Use Classification: Chemical Classes -> Benzidines, Aromatic amines, Industry Uses: Surface modifier, Intermediate, Other, Methods of Manufacturing: ... From aniline and formaldehyde, ... By hydrogenolysis of p, p'-diaminobenzophenone with LiAlH4., Acid-catalyzed reaction of formaldehyde with aniline, distillation from polymeric 4, 4'-diaminodiphenylmethane., Impurities: 2, 4-diaminodiphenylmethane isomer, up to 3%, Formulations, Preparations: With a diamine assay of 98-99%, Sold in flaked or granular form, U.S. Production: 2023: 1, 000, 000 - <5, 000 lb, 2022: 1, 000 - <2, 500, 2021: 1, 2020: 1, (1972 SALES) 8.57X10+8 G, (1975) 4.10X10+8 G (SALES), Benzenamine, 4'-methylenebis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#4022], U.S. Imports: (1972) 1.6X10+6 G, (1974) 1.00X10+6 G, General Manufacturing Information: Adhesive Manufacturing, All Other Chemical Product and Preparation Manufacturing, Plastics Material and Resin Manufacturing, 4'-methylenebis-: ACTIVE.

Technical Profile

What this product is

4,4'-Diaminodiphenylmethane is a chemical compound with CAS registry number 1219795-26-2 and molecular formula C13H14N2 (molecular weight 198.26), belonging to the chemical segment of chemical raw materials.

Identification

CAS number: 1219795-26-2

Its molecular formula C13H14N2 comprises 13 C, 14 H, 2 N atoms.

Also known as: 4,4'-Diaminodiphenylmethane · 4,4-二氨基二苯甲烷

Category: chemical

Frequently Asked Questions

What is the CAS number of 4,4'-Diaminodiphenylmethane?

The CAS registry number of 4,4'-Diaminodiphenylmethane is 1219795-26-2.

What is the molecular formula and molecular weight of 4,4'-Diaminodiphenylmethane?

Molecular formula C13H14N2, molecular weight 198.26.

What other names is 4,4'-Diaminodiphenylmethane known by?

It is also registered under: 4,4'-Diaminodiphenylmethane, 4,4-二氨基二苯甲烷.

What are the documented applications of 4,4'-Diaminodiphenylmethane?

Recorded applications: Uses: MDA is primarily used to produce 4, 4-'methylenedianiline diisocyanate and other polymeric isocyanates which are used to manufacture polyurethane foams. MDA is also used as a curing agent for epoxy resins and urethane elastomers, as a corrosion preventative for iron, as an antioxidant for lubricating oils, as a rubber processing chemical, as an intermediate in the manufacture of elastomeric fibers (e.g., Spandex), and in the preparation of azo dyes., Used as a chemical intermediate, lab analytic agent, and monomer for polyamide and polymide resins, [HSDB] Used primarily in the manufacture of rubber and plastics, used as an epoxy resin hardener in the following applications: glues, paints, inks, polyvinylchloride products, dental bonding agents, and microelectronic encapsulations, [Marks, p. 269], Carcinogen--See 29 CFR 1910.1050, Plastic Composites Manufacturing [Category: Industry], As chemical intermediate in prodn of isocyanates and polyisocyanates for prepn of polyurethane foams, Spandex fibers, as curing agent for epoxy resins and urethane elastomers, in production of polyamides, in the determination of tungsten and sulfates, in prepn of azo dyes, as corrosion inhibitor., Determination of tungsten and sulfates, polymer and dye intermediate, corrosion inhibitor, epoxy-resin hardening agent, isocyanate resins, polyamides., The isocyanates developed from 4, 4'-methylenedianiline are also incorporated into semiflexible polyurethane foams for automobile safety cushioning., 4, 4'-Methylenediphenyl diisocyanate produced from the highly purified 4, 4'-methylene dianiline isomer is used for the manufacture of elastomers such as spandex fibres., For more Uses (Complete) data for 4, 4'-DIAMINODIPHENYLMETHANE (6 total), please visit the HSDB record page., Substance listed with specific concentration in tattoo ink and, or permanent make up according to EU Commission Regulation 2020, 2081. The concentration limit (by weight) is 0.0005%., Use Classification: Chemical Classes -> Benzidines, Aromatic amines, Industry Uses: Surface modifier, Intermediate, Other, Methods of Manufacturing: ... From aniline and formaldehyde, ... By hydrogenolysis of p, p'-diaminobenzophenone with LiAlH4., Acid-catalyzed reaction of formaldehyde with aniline, distillation from polymeric 4, 4'-diaminodiphenylmethane., Impurities: 2, 4-diaminodiphenylmethane isomer, up to 3%, Formulations, Preparations: With a diamine assay of 98-99%, Sold in flaked or granular form, U.S. Production: 2023: 1, 000, 000 - <5, 000 lb, 2022: 1, 000 - <2, 500, 2021: 1, 2020: 1, (1972 SALES) 8.57X10+8 G, (1975) 4.10X10+8 G (SALES), Benzenamine, 4'-methylenebis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#4022], U.S. Imports: (1972) 1.6X10+6 G, (1974) 1.00X10+6 G, General Manufacturing Information: Adhesive Manufacturing, All Other Chemical Product and Preparation Manufacturing, Plastics Material and Resin Manufacturing, 4'-methylenebis-: ACTIVE.

Which category does 4,4'-Diaminodiphenylmethane belong to?

Category: 医药Intermediates.

PubChem Public Data

Independent reference data for 4,4'-Diaminodiphenylmethane (CAS 1219795-26-2), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number1219795-26-2
PubChem CID7577
Molecular formulaC13H14N2
IUPAC name4-[(4-aminophenyl)methyl]aniline
UNII (FDA)GG5LL7OBZC

Computed descriptors

Molecular Weight198.26
XLogP31.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass198.115698455
Monoisotopic Mass198.115698455
Topological Polar Surface Area52
Heavy Atom Count15

Physicochemical values on record

Boiling Point748 to 750 °F at 768 mmHg (NTP, 1992)
Boiling Point398 °C
Boiling Pointat 102kPa: 398-399 °C
Boiling Point748 °F
Boiling Point398 °C @760 [mm Hg]
Melting Point197 to 198 °F (NTP, 1992)
Melting Point92.5 °C
Melting Point91.5-92 °C
Melting Point198 °F
Flash Point430 °F (NTP, 1992)

Documented uses on record

    MDA is primarily used to produce 4,4-'methylenedianiline diisocyanate and other polymeric isocyanates which are used to manufacture polyurethane foams. MDA is also used as a curing agent for epoxy resins and urethane elastomers, as a corrosion preventative for iron, as an antioxidant for lubricating oils, as a rubber processing chemical, as an intermediate in the manufacture of elastomeric fibers (e.g., Spandex), and in the preparation of azo dyes.Used as a chemical intermediate, lab analytic agent, and monomer for polyamide and polymide resins; [HSDB] Used primarily in the manufacture of rubber and plastics; used as an epoxy resin hardener in the following applications: glues, paints, inks, polyvinylchloride products, dental bonding agents, and microelectronic encapsulations; [Marks, p. 269]

    Synonyms and trade names

    4,4'-Methylenedianiline; 101-77-9; 4,4'-DIAMINODIPHENYLMETHANE; Dadpm; Methylenedianiline; 4-[(4-aminophenyl)methyl]aniline; Bis(4-aminophenyl)methane; Dianilinemethane; Dianilinomethane; p,p'-Methylenedianiline; Epicure DDM; Epikure DDM; Curithane; 4-(4-Aminobenzyl)aniline; Benzenamine, 4,4'-methylenebis-; Jeffamine AP-20

    Regulatory listings held on file

    Regulatory & Food ContactFDA Cumulative Estimated Daily Intake (CEDI): FCS
    FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS

    GHS hazard classification

    Reported hazard statementsH317, H341, H350, H370, H373, H411, H301 (14.5%), H400 (28.5%)

    H317: May cause an allergic skin reaction [Warning Sensitization, Skin]

    H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]

    What the public record says

    4,4-Diaminodiphenylmethane · CAS 1219795-26-2 · C13H14N2. UNII GG5LL7OBZC. Boiling Point: 748 to 750 °F at 768 mmHg (NTP, 1992); Boiling Point: 398 °C; Boiling Point: at 102kPa: 398-399 °C.

    Physical description and handling notes

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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