Mitomycin (CAS 50-07-7) — formula C15H18N4O5, molecular weight 334.33; category organic chemicals.
| CAS Number | 50-07-7 |
|---|---|
| Molecular Formula | C15H18N4O5 |
| Molecular Weight | 334.33 |
| Melting Point | Above 680 °F (EPA, 1998) |
| Boiling Point | 534 |
| LogP | -0.4 |
| Applications | Uses: Used as an alkylating agent in cancer chemotherapy, [HSDB], MEDICATION, For treatment of malignant neoplasm of lip, oral cavity, pharynx, digestive organs, peritoneum, female breast, and urinary bladder. Also used as an adjunct to ab externo glaucoma surgery., Methods of Manufacturing: PRODUCED BY STREPTOMYCES CAESPITOSUS (GRISEOVINACESEUS)., Yamamoto, Kenkyusho, Japan pat. 2898 (1956), Brit. pat. 830, 874 (1960 to Kyowa), Gourevitch et al, U.S. pat. 3, 042583 (1962 to Bristol-Myers), production of the complex, ...derived from Streptomyces, Formulations, Preparations: MUTAMYCIN ... INJECTION: POWDER 5 MG., Mitomycin ... available as deep blue-violet crystals in vials containing 5, 20, or 40 mg ... administered by intravenous infusion., Mitomycin for injection is a dry mixture of Mitomycin and Mannitol. It contains not less than 90.0% and not more than 120.0% of the labeled amount of mitomycin C., Mitomycin has a potency of not less than 900 ug of mitomycin C per mg., General Manufacturing Information: Azirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methyl-, (1aS, 8S, 8aR, 8bS)-: ACTIVE |
| Category | Organic Chemicals |
Documented applications: Uses: Used as an alkylating agent in cancer chemotherapy, [HSDB], MEDICATION, For treatment of malignant neoplasm of lip, oral cavity, pharynx, digestive organs, peritoneum, female breast, and urinary bladder. Also used as an adjunct to ab externo glaucoma surgery., Methods of Manufacturing: PRODUCED BY STREPTOMYCES CAESPITOSUS (GRISEOVINACESEUS)., Yamamoto, Kenkyusho, Japan pat. 2898 (1956), Brit. pat. 830, 874 (1960 to Kyowa), Gourevitch et al, U.S. pat. 3, 042583 (1962 to Bristol-Myers), production of the complex, ...derived from Streptomyces, Formulations, Preparations: MUTAMYCIN ... INJECTION: POWDER 5 MG., Mitomycin ... available as deep blue-violet crystals in vials containing 5, 20, or 40 mg ... administered by intravenous infusion., Mitomycin for injection is a dry mixture of Mitomycin and Mannitol. It contains not less than 90.0% and not more than 120.0% of the labeled amount of mitomycin C., Mitomycin has a potency of not less than 900 ug of mitomycin C per mg., General Manufacturing Information: Azirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methyl-, (1aS, 8S, 8aR, 8bS)-: ACTIVE.
Mitomycin is a carbon-based organic compound with CAS registry number 50-07-7 and molecular formula C15H18N4O5 (molecular weight 334.33), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 50-07-7
Its molecular formula C15H18N4O5 comprises 15 C, 18 H, 4 N, 5 O atoms.
Also known as: Mitomycin · 丝裂霉素
Category: organic chemicals
The CAS registry number of Mitomycin is 50-07-7.
Molecular formula C15H18N4O5, molecular weight 334.33.
It is also registered under: Mitomycin, 丝裂霉素.
Recorded applications: Uses: Used as an alkylating agent in cancer chemotherapy, [HSDB], MEDICATION, For treatment of malignant neoplasm of lip, oral cavity, pharynx, digestive organs, peritoneum, female breast, and urinary bladder. Also used as an adjunct to ab externo glaucoma surgery., Methods of Manufacturing: PRODUCED BY STREPTOMYCES CAESPITOSUS (GRISEOVINACESEUS)., Yamamoto, Kenkyusho, Japan pat. 2898 (1956), Brit. pat. 830, 874 (1960 to Kyowa), Gourevitch et al, U.S. pat. 3, 042583 (1962 to Bristol-Myers), production of the complex, ...derived from Streptomyces, Formulations, Preparations: MUTAMYCIN ... INJECTION: POWDER 5 MG., Mitomycin ... available as deep blue-violet crystals in vials containing 5, 20, or 40 mg ... administered by intravenous infusion., Mitomycin for injection is a dry mixture of Mitomycin and Mannitol. It contains not less than 90.0% and not more than 120.0% of the labeled amount of mitomycin C., Mitomycin has a potency of not less than 900 ug of mitomycin C per mg., General Manufacturing Information: Azirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methyl-, (1aS, 8S, 8aR, 8bS)-: ACTIVE.
Category: Organic Chemicals.
Independent reference data for Mitomycin (CAS 50-07-7), compiled from public chemistry databases.
| CAS Registry Number | 50-07-7 |
|---|---|
| PubChem CID | 5746 |
| Molecular formula | C15H18N4O5 |
| IUPAC name | [(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate |
| UNII (FDA) | 50SG953SK6 |
| Molecular Weight | 334.33 |
|---|---|
| XLogP3 | -0.4 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 4 |
| Exact Mass | 334.12771969 |
| Monoisotopic Mass | 334.12771969 |
| Topological Polar Surface Area | 147 |
| Heavy Atom Count | 24 |
| Boiling Point | 534 |
|---|---|
| Melting Point | Above 680 °F (EPA, 1998) |
| Melting Point | >360 °C |
| Melting Point | ABOVE 360 °C |
| Melting Point | > 360 °C |
| Solubility | Soluble (8430 mg/L) |
| Solubility | 1.01e+01 g/L |
| LogP | -0.4 |
| LogP | logP = -0.40 |
| LogP | -1.6 |
mitomycin C; Mitomycin; 50-07-7; Mutamycin; Ametycine; Mitomycin-C; Mitocin-C; Ametycin; Mitomycinum; Mytomycin; Mytozytrex; Mitomycinum C; Mitocin C; Mitamycin; Mitosol; NSC-26980
| Reported hazard statements | H300 (75.4%), H301 (21.7%), H351 (94.2%) |
|---|
H300 (75.4%): Fatal if swallowed [Danger Acute toxicity, oral]
H301 (21.7%): Toxic if swallowed [Danger Acute toxicity, oral]
Mitomycin · CAS 50-07-7 · C15H18N4O5. UNII 50SG953SK6. Boiling Point: 534; Melting Point: Above 680 °F (EPA, 1998); Melting Point: >360 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 丝裂霉素