丝裂霉素（CAS 50-07-7）：分子式 C15H18N4O5、分子量 334.33。
| CAS号 | 50-07-7 |
|---|---|
| 分子式 | C15H18N4O5 |
| 分子量 | 334.33 |
| 熔点 | Above 680 °F (EPA, 1998) |
| 沸点 | 534 |
| LogP | -0.4 |
| 应用领域 | Uses: Used as an alkylating agent in cancer chemotherapy、[HSDB]、MEDICATION、For treatment of malignant neoplasm of lip、oral cavity、pharynx、digestive organs、peritoneum、female breast、and urinary bladder. Also used as an adjunct to ab externo glaucoma surgery.、Methods of Manufacturing: PRODUCED BY STREPTOMYCES CAESPITOSUS (GRISEOVINACESEUS).、Yamamoto、Kenkyusho、Japan pat. 2898 (1956)、Brit. pat. 830、874 (1960 to Kyowa)、Gourevitch et al、U.S. pat. 3、042583 (1962 to Bristol-Myers)、production of the complex、...derived from Streptomyces、Formulations、Preparations: MUTAMYCIN ... INJECTION: POWDER 5 MG.、Mitomycin ... available as deep blue-violet crystals in vials containing 5、20、or 40 mg ... administered by intravenous infusion.、Mitomycin for injection is a dry mixture of Mitomycin and Mannitol. It contains not less than 90.0% and not more than 120.0% of the labeled amount of mitomycin C.、Mitomycin has a potency of not less than 900 ug of mitomycin C per mg.、General Manufacturing Information: Azirino[2'、3':3、4]pyrrolo[1、2-a]indole-4、7-dione、6-amino-8-[[(aminocarbonyl)oxy]methyl]-1、1a、2、8、8a、8b-hexahydro-8a-methoxy-5-methyl-、(1aS、8S、8aR、8bS)-: ACTIVE |
登记用途：Uses: Used as an alkylating agent in cancer chemotherapy、[HSDB]、MEDICATION、For treatment of malignant neoplasm of lip、oral cavity、pharynx、digestive organs、peritoneum、female breast、and urinary bladder. Also used as an adjunct to ab externo glaucoma surgery.、Methods of Manufacturing: PRODUCED BY STREPTOMYCES CAESPITOSUS (GRISEOVINACESEUS).、Yamamoto、Kenkyusho、Japan pat. 2898 (1956)、Brit. pat. 830、874 (1960 to Kyowa)、Gourevitch et al、U.S. pat. 3、042583 (1962 to Bristol-Myers)、production of the complex、...derived from Streptomyces、Formulations、Preparations: MUTAMYCIN ... INJECTION: POWDER 5 MG.、Mitomycin ... available as deep blue-violet crystals in vials containing 5、20、or 40 mg ... administered by intravenous infusion.、Mitomycin for injection is a dry mixture of Mitomycin and Mannitol. It contains not less than 90.0% and not more than 120.0% of the labeled amount of mitomycin C.、Mitomycin has a potency of not less than 900 ug of mitomycin C per mg.、General Manufacturing Information: Azirino[2'、3':3、4]pyrrolo[1、2-a]indole-4、7-dione、6-amino-8-[[(aminocarbonyl)oxy]methyl]-1、1a、2、8、8a、8b-hexahydro-8a-methoxy-5-methyl-、(1aS、8S、8aR、8bS)-: ACTIVE。
丝裂霉素 是一种化工化合物，登记 CAS 号为 50-07-7，分子式 C15H18N4O5（分子量 334.33）。
登记 CAS 号：50-07-7
其分子式 C15H18N4O5 由 15 个碳、18 个氢、4 个氮、5 个氧 组成。
别名/同义词：丝裂霉素 · Mitomycin
丝裂霉素 的 CAS 登记号为 50-07-7。
分子式 C15H18N4O5，分子量 334.33。
别名/同义词：丝裂霉素、Mitomycin。
登记用途：Uses: Used as an alkylating agent in cancer chemotherapy、[HSDB]、MEDICATION、For treatment of malignant neoplasm of lip、oral cavity、pharynx、digestive organs、peritoneum、female breast、and urinary bladder. Also used as an adjunct to ab externo glaucoma surgery.、Methods of Manufacturing: PRODUCED BY STREPTOMYCES CAESPITOSUS (GRISEOVINACESEUS).、Yamamoto、Kenkyusho、Japan pat. 2898 (1956)、Brit. pat. 830、874 (1960 to Kyowa)、Gourevitch et al、U.S. pat. 3、042583 (1962 to Bristol-Myers)、production of the complex、...derived from Streptomyces、Formulations、Preparations: MUTAMYCIN ... INJECTION: POWDER 5 MG.、Mitomycin ... available as deep blue-violet crystals in vials containing 5、20、or 40 mg ... administered by intravenous infusion.、Mitomycin for injection is a dry mixture of Mitomycin and Mannitol. It contains not less than 90.0% and not more than 120.0% of the labeled amount of mitomycin C.、Mitomycin has a potency of not less than 900 ug of mitomycin C per mg.、General Manufacturing Information: Azirino[2'、3':3、4]pyrrolo[1、2-a]indole-4、7-dione、6-amino-8-[[(aminocarbonyl)oxy]methyl]-1、1a、2、8、8a、8b-hexahydro-8a-methoxy-5-methyl-、(1aS、8S、8aR、8bS)-: ACTIVE。
丝裂霉素（CAS 50-07-7）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 50-07-7 |
|---|---|
| PubChem CID | 5746 |
| Molecular formula | C15H18N4O5 |
| IUPAC name | [(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate |
| UNII (FDA) | 50SG953SK6 |
| Molecular Weight | 334.33 |
|---|---|
| XLogP3 | -0.4 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 4 |
| Exact Mass | 334.12771969 |
| Monoisotopic Mass | 334.12771969 |
| Topological Polar Surface Area | 147 |
| Heavy Atom Count | 24 |
| Boiling Point | 534 |
|---|---|
| Melting Point | Above 680 °F (EPA, 1998) |
| Melting Point | >360 °C |
| Melting Point | ABOVE 360 °C |
| Melting Point | > 360 °C |
| Solubility | Soluble (8430 mg/L) |
| Solubility | 1.01e+01 g/L |
| LogP | -0.4 |
| LogP | logP = -0.40 |
| LogP | -1.6 |
mitomycin C; Mitomycin; 50-07-7; Mutamycin; Ametycine; Mitomycin-C; Mitocin-C; Ametycin; Mitomycinum; Mytomycin; Mytozytrex; Mitomycinum C; Mitocin C; Mitamycin; Mitosol; NSC-26980
| Reported hazard statements | H300 (75.4%), H301 (21.7%), H351 (94.2%) |
|---|
H300 (75.4%): Fatal if swallowed [Danger Acute toxicity, oral]
H301 (21.7%): Toxic if swallowed [Danger Acute toxicity, oral]
Mitomycin · CAS 50-07-7 · C15H18N4O5. UNII 50SG953SK6. Boiling Point: 534; Melting Point: Above 680 °F (EPA, 1998); Melting Point: >360 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Mitomycin