Vitamin D2（CAS 50-14-6）：分子式 C28H44O、分子量 396.6；类别 食品添加剂。
| CAS号 | 50-14-6 |
|---|---|
| 分子式 | C28H44O |
| 分子量 | 396.6 |
| 熔点 | 239 to 244 °F (EPA, 1998) |
| LogP | 8.89 |
| 应用领域 | Uses: Synthetic form of vitamin D used as a rodenticide and therapeutic vitamin、[Merck Index] Used as a nutritional supplement、[FDA]、No active pesticide product registrations in the US、[NPIRS]、MEDICATION、MEDICATION (VET)、Rodenticide.、For use in the management of hypocalcemia and its clinical manifestations in patients with hypoparathyroidism、as well as for the treatment of familial hypophosphatemia (vitamin D resistant rickets). This drug has also been used in the treatment of nutritional rickets or osteomalacia、vitamin D dependent rickets、rickets or osteomalacia secondary to long-term high dose anticonvulsant therapy、early renal osteodystrophy、osteoporosis (in conjunction with calcium)、and hypophosphatemia associated with Fanconi syndrome (with treatment of acidosis).、Household Products: Information on 1 consumer products that contain Ergocalciferol in the following categories is provided:、• Personal Care、Methods of Manufacturing:、Is、the synthetic form of vitamin D. Prepared from ergosterol by UV irradiation in a suitable solvent. ... The best wavelengths for production of vitamin D2 seem to be from 275 to 300 nm ... Prepn by electron bombardment of ergosterol using longer waves ... .、Usually obtained from yeast which synthesizes it from simple sugars such as glucose.、Formulations、Preparations: Ergocalciferol capsules usually consist of the drug in an edible oil solution encapsulated with gelatin. Commercially available ergocalciferol solution is a clear solution of the drug in an edible vegetable oil or in propylene glycol. Ergocalciferol injection is a sterile solution of the drug in sesame oil.、Ergocalciferol is also commercially available in combination with other vitamins and minerals、analgesic-antipyretics、amino acids、infant formulas、laxatives、and protein supplements.、Parenteral: Injection (for IM use only): 12.5 mg (500、000 units) per mL、Calciferol (in oil)、(Schwarz)、Ergocalciferol (calciferol、Drisdol) is pure vitamin D2. ... Available in capsules or tablets that contain 1.25 mg (50、000 USP units) each. An oral solution (8、000 units、mL) of the vitamin in propylene glycol is also available. An injection in oil (500、mL) is available for im administration. ... Dihydrotachysterol (DHT、hytakerol) is the pure crystalline compound obtained by reduction of vitamin D2 ... Available as tablets (0.125 to 0.4 mg)、capsules (0.125 mg)、an oral soln (0.2 mg、mL) & a soln in oil (0.2 mg、mL).、For more Formulations、Preparations (Complete) data for VITAMIN D2 (7 total)、please visit the HSDB record page.、U.S. Imports: (1984) 9.16X10+7 g、Vitamin D-2 and D-3、synthetic、General Manufacturing Information: Cyclohexanol、4-methylene-3-[(2E)-2-[(1R、3aS、7aR)-octahydro-7a-methyl-1-[(1R、2E、4R)-1、4、5-trimethyl-2-hexen-1-yl]-4H-inden-4-ylidene]ethylidene]-、(1S、3Z)-: ACTIVE、Information available in 2004 indicated that Ergocalciferol was used in the manufacture of pharmaceutical preparations in the following countries: Argentina、Australia、Austria、Brazil、Canada、Chile、Czech Republic、Denmark、Ecuador、Finland、France、Germany、Greece、Hong Kong、Ireland、Israel、Italy、Luxembourg、Malaysia、Mexico、Norway、Portugal、Romania、Slovakia、South Africa、Spain、Switzerland、Thailand、United Kingdom、USA (1、2)、International & USP units of vitamin D are equivalent in activity to 0.025 ug of crystalline vitamin D2.、Ergosterol、which is present in plants、is provitamin for vitamin D2 (calciferol). ... Vitamin D2 is active constituent in a number of commercial vitamin preparations as well as in irradiated bread & irradiated milk.、Vitamin D2 crystals have a potency of 40 units of vitamin D (USP)、ug.、Because of vitamin D2's sensitivity to oxygen and light、USP allows traces of antioxidants in crystalline compound. |
| 类别 | 营养强化剂 |
登记用途：Uses: Synthetic form of vitamin D used as a rodenticide and therapeutic vitamin、[Merck Index] Used as a nutritional supplement、[FDA]、No active pesticide product registrations in the US、[NPIRS]、MEDICATION、MEDICATION (VET)、Rodenticide.、For use in the management of hypocalcemia and its clinical manifestations in patients with hypoparathyroidism、as well as for the treatment of familial hypophosphatemia (vitamin D resistant rickets). This drug has also been used in the treatment of nutritional rickets or osteomalacia、vitamin D dependent rickets、rickets or osteomalacia secondary to long-term high dose anticonvulsant therapy、early renal osteodystrophy、osteoporosis (in conjunction with calcium)、and hypophosphatemia associated with Fanconi syndrome (with treatment of acidosis).、Household Products: Information on 1 consumer products that contain Ergocalciferol in the following categories is provided:、• Personal Care、Methods of Manufacturing:、Is、the synthetic form of vitamin D. Prepared from ergosterol by UV irradiation in a suitable solvent. ... The best wavelengths for production of vitamin D2 seem to be from 275 to 300 nm ... Prepn by electron bombardment of ergosterol using longer waves ... .、Usually obtained from yeast which synthesizes it from simple sugars such as glucose.、Formulations、Preparations: Ergocalciferol capsules usually consist of the drug in an edible oil solution encapsulated with gelatin. Commercially available ergocalciferol solution is a clear solution of the drug in an edible vegetable oil or in propylene glycol. Ergocalciferol injection is a sterile solution of the drug in sesame oil.、Ergocalciferol is also commercially available in combination with other vitamins and minerals、analgesic-antipyretics、amino acids、infant formulas、laxatives、and protein supplements.、Parenteral: Injection (for IM use only): 12.5 mg (500、000 units) per mL、Calciferol (in oil)、(Schwarz)、Ergocalciferol (calciferol、Drisdol) is pure vitamin D2. ... Available in capsules or tablets that contain 1.25 mg (50、000 USP units) each. An oral solution (8、000 units、mL) of the vitamin in propylene glycol is also available. An injection in oil (500、mL) is available for im administration. ... Dihydrotachysterol (DHT、hytakerol) is the pure crystalline compound obtained by reduction of vitamin D2 ... Available as tablets (0.125 to 0.4 mg)、capsules (0.125 mg)、an oral soln (0.2 mg、mL) & a soln in oil (0.2 mg、mL).、For more Formulations、Preparations (Complete) data for VITAMIN D2 (7 total)、please visit the HSDB record page.、U.S. Imports: (1984) 9.16X10+7 g、Vitamin D-2 and D-3、synthetic、General Manufacturing Information: Cyclohexanol、4-methylene-3-[(2E)-2-[(1R、3aS、7aR)-octahydro-7a-methyl-1-[(1R、2E、4R)-1、4、5-trimethyl-2-hexen-1-yl]-4H-inden-4-ylidene]ethylidene]-、(1S、3Z)-: ACTIVE、Information available in 2004 indicated that Ergocalciferol was used in the manufacture of pharmaceutical preparations in the following countries: Argentina、Australia、Austria、Brazil、Canada、Chile、Czech Republic、Denmark、Ecuador、Finland、France、Germany、Greece、Hong Kong、Ireland、Israel、Italy、Luxembourg、Malaysia、Mexico、Norway、Portugal、Romania、Slovakia、South Africa、Spain、Switzerland、Thailand、United Kingdom、USA (1、2)、International & USP units of vitamin D are equivalent in activity to 0.025 ug of crystalline vitamin D2.、Ergosterol、which is present in plants、is provitamin for vitamin D2 (calciferol). ... Vitamin D2 is active constituent in a number of commercial vitamin preparations as well as in irradiated bread & irradiated milk.、Vitamin D2 crystals have a potency of 40 units of vitamin D (USP)、ug.、Because of vitamin D2's sensitivity to oxygen and light、USP allows traces of antioxidants in crystalline compound.。
Vitamin D2 是一种食品级化合物，登记 CAS 号为 50-14-6，分子式 C28H44O（分子量 396.6），归属于食品添加剂大类化工原料。
登记 CAS 号：50-14-6
其分子式 C28H44O 由 28 个碳、44 个氢、1 个氧 组成。
别名/同义词：Vitamin D2 · Vitamin D2 oil
所属分类：食品添加剂
Vitamin D2 的 CAS 登记号为 50-14-6。
分子式 C28H44O，分子量 396.6。
别名/同义词：Vitamin D2、Vitamin D2 oil。
登记用途：Uses: Synthetic form of vitamin D used as a rodenticide and therapeutic vitamin、[Merck Index] Used as a nutritional supplement、[FDA]、No active pesticide product registrations in the US、[NPIRS]、MEDICATION、MEDICATION (VET)、Rodenticide.、For use in the management of hypocalcemia and its clinical manifestations in patients with hypoparathyroidism、as well as for the treatment of familial hypophosphatemia (vitamin D resistant rickets). This drug has also been used in the treatment of nutritional rickets or osteomalacia、vitamin D dependent rickets、rickets or osteomalacia secondary to long-term high dose anticonvulsant therapy、early renal osteodystrophy、osteoporosis (in conjunction with calcium)、and hypophosphatemia associated with Fanconi syndrome (with treatment of acidosis).、Household Products: Information on 1 consumer products that contain Ergocalciferol in the following categories is provided:、• Personal Care、Methods of Manufacturing:、Is、the synthetic form of vitamin D. Prepared from ergosterol by UV irradiation in a suitable solvent. ... The best wavelengths for production of vitamin D2 seem to be from 275 to 300 nm ... Prepn by electron bombardment of ergosterol using longer waves ... .、Usually obtained from yeast which synthesizes it from simple sugars such as glucose.、Formulations、Preparations: Ergocalciferol capsules usually consist of the drug in an edible oil solution encapsulated with gelatin. Commercially available ergocalciferol solution is a clear solution of the drug in an edible vegetable oil or in propylene glycol. Ergocalciferol injection is a sterile solution of the drug in sesame oil.、Ergocalciferol is also commercially available in combination with other vitamins and minerals、analgesic-antipyretics、amino acids、infant formulas、laxatives、and protein supplements.、Parenteral: Injection (for IM use only): 12.5 mg (500、000 units) per mL、Calciferol (in oil)、(Schwarz)、Ergocalciferol (calciferol、Drisdol) is pure vitamin D2. ... Available in capsules or tablets that contain 1.25 mg (50、000 USP units) each. An oral solution (8、000 units、mL) of the vitamin in propylene glycol is also available. An injection in oil (500、mL) is available for im administration. ... Dihydrotachysterol (DHT、hytakerol) is the pure crystalline compound obtained by reduction of vitamin D2 ... Available as tablets (0.125 to 0.4 mg)、capsules (0.125 mg)、an oral soln (0.2 mg、mL) & a soln in oil (0.2 mg、mL).、For more Formulations、Preparations (Complete) data for VITAMIN D2 (7 total)、please visit the HSDB record page.、U.S. Imports: (1984) 9.16X10+7 g、Vitamin D-2 and D-3、synthetic、General Manufacturing Information: Cyclohexanol、4-methylene-3-[(2E)-2-[(1R、3aS、7aR)-octahydro-7a-methyl-1-[(1R、2E、4R)-1、4、5-trimethyl-2-hexen-1-yl]-4H-inden-4-ylidene]ethylidene]-、(1S、3Z)-: ACTIVE、Information available in 2004 indicated that Ergocalciferol was used in the manufacture of pharmaceutical preparations in the following countries: Argentina、Australia、Austria、Brazil、Canada、Chile、Czech Republic、Denmark、Ecuador、Finland、France、Germany、Greece、Hong Kong、Ireland、Israel、Italy、Luxembourg、Malaysia、Mexico、Norway、Portugal、Romania、Slovakia、South Africa、Spain、Switzerland、Thailand、United Kingdom、USA (1、2)、International & USP units of vitamin D are equivalent in activity to 0.025 ug of crystalline vitamin D2.、Ergosterol、which is present in plants、is provitamin for vitamin D2 (calciferol). ... Vitamin D2 is active constituent in a number of commercial vitamin preparations as well as in irradiated bread & irradiated milk.、Vitamin D2 crystals have a potency of 40 units of vitamin D (USP)、ug.、Because of vitamin D2's sensitivity to oxygen and light、USP allows traces of antioxidants in crystalline compound.。
所属分类：营养强化剂。
Vitamin D2（CAS 50-14-6）的独立参考数据，整理自公开化学数据库。
| CAS 号 | 50-14-6 |
|---|---|
| PubChem CID | 5280793 |
| 分子式 | C28H44O |
| IUPAC 名称 | (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol |
| UNII（FDA） | VS041H42XC |
| Molecular Weight | 396.6 |
|---|---|
| XLogP3 | 7.4 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 5 |
| Exact Mass | 396.339216023 |
| Monoisotopic Mass | 396.339216023 |
| Topological Polar Surface Area | 20.2 |
| Heavy Atom Count | 29 |
| Melting Point | 239 to 244 °F (EPA, 1998) |
|---|---|
| Melting Point | 115-117°C |
| Melting Point | 116.5 °C |
| Solubility | In water, 50 mg/L at 25 °C |
| Solubility | 0.05 mg/mL |
| LogP | 8.89 |
| Dissociation Constants | 6.35 |
ergocalciferol; VITAMIN D2; Calciferol; 50-14-6; Viosterol; Deltalin; Ergorone; Oleovitamin D2; Drisdol; Ostelin; Ercalciol; Sterogyl; Detalup; Condocaps; Crystallina; Fortodyl
| 法规与食品接触 | FDA Substance added to food: NUTRIENT SUPPLEMENT VITAMIN D-2 |
|---|
| 已通报的危害声明 | H301, H311, H330, H372, H300, H310, H413 (41.8%) |
|---|
维生素 D2 油·CAS 50-14-6·C28H44O。 UNII VS041H42XC。熔点：239 至 244 °F（EPA，1998）；熔点：115-117℃；熔点：116.5℃。
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Vitamin D2