Trazodone (CAS 19794-93-5) — formula C19H22ClN5O, molecular weight 371.9; category organic chemicals.
| CAS Number | 19794-93-5 |
|---|---|
| Molecular Formula | C19H22ClN5O |
| Molecular Weight | 371.9 |
| Melting Point | 231-234 |
| Boiling Point | 528.5 |
| LogP | 2.68 |
| Applications | Uses: Anti-Anxiety Agents, Antidepressive Agents, Second-Generation, Serotonin Uptake Inhibitors, MEDICATION, MEDICATION (VET), Use (kg, approx.) in Germany (2009): >500, Use (kg) in USA (2002): 20900, Consumption (g per capita, approx.) in Germany (2009): 0.00611, Consumption (g per capita) in the USA (2002): 0.0741, Calculated removal (%): 7.9, For the treatment of depression., Use Classification: Pharmaceuticals, Methods of Manufacturing: Semicarbazide and 2-chloropyridine are condensed with loss of water and ammonia to form 1, 2, 4-triazolo[4, 3-alpha]pyridin3(2H)-one, with on treatment with 1-(3-chlorophenyl)4, 3-chlorophenyl)piperazine and sodamide, yields trazodone., Impurities: ...1-(3-chloropropyl)-4-(3-chlorophenyl)piperazine HCl (CCP HCl) a process related impurity in trazodone., Genotoxic Impurity, Formulations, Preparations: Beneficat, Depyrel, Taxagon, Trazodil, AF-1161, Molipaxin, Oleptro, Thombran, Trazolan, Trittico., Trazodone hydrochloride, The main ingredient in the drug Desyrel ... (tablets), Table: Trazodone Hydrochloride Preparations [Table#6674] |
| Category | Organic Chemicals |
Documented applications: Uses: Anti-Anxiety Agents, Antidepressive Agents, Second-Generation, Serotonin Uptake Inhibitors, MEDICATION, MEDICATION (VET), Use (kg, approx.) in Germany (2009): >500, Use (kg) in USA (2002): 20900, Consumption (g per capita, approx.) in Germany (2009): 0.00611, Consumption (g per capita) in the USA (2002): 0.0741, Calculated removal (%): 7.9, For the treatment of depression., Use Classification: Pharmaceuticals, Methods of Manufacturing: Semicarbazide and 2-chloropyridine are condensed with loss of water and ammonia to form 1, 2, 4-triazolo[4, 3-alpha]pyridin3(2H)-one, with on treatment with 1-(3-chlorophenyl)4, 3-chlorophenyl)piperazine and sodamide, yields trazodone., Impurities: ...1-(3-chloropropyl)-4-(3-chlorophenyl)piperazine HCl (CCP HCl) a process related impurity in trazodone., Genotoxic Impurity, Formulations, Preparations: Beneficat, Depyrel, Taxagon, Trazodil, AF-1161, Molipaxin, Oleptro, Thombran, Trazolan, Trittico., Trazodone hydrochloride, The main ingredient in the drug Desyrel ... (tablets), Table: Trazodone Hydrochloride Preparations [Table#6674].
Trazodone is a carbon-based organic compound with CAS registry number 19794-93-5 and molecular formula C19H22ClN5O (molecular weight 371.9), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 19794-93-5
Its molecular formula C19H22ClN5O comprises 19 C, 22 H, 1 Cl, 5 N, 1 O atoms.
Also known as: Trazodone · 曲唑酮
Category: organic chemicals
The CAS registry number of Trazodone is 19794-93-5.
Molecular formula C19H22ClN5O, molecular weight 371.9.
It is also registered under: Trazodone, 曲唑酮.
Recorded applications: Uses: Anti-Anxiety Agents, Antidepressive Agents, Second-Generation, Serotonin Uptake Inhibitors, MEDICATION, MEDICATION (VET), Use (kg, approx.) in Germany (2009): >500, Use (kg) in USA (2002): 20900, Consumption (g per capita, approx.) in Germany (2009): 0.00611, Consumption (g per capita) in the USA (2002): 0.0741, Calculated removal (%): 7.9, For the treatment of depression., Use Classification: Pharmaceuticals, Methods of Manufacturing: Semicarbazide and 2-chloropyridine are condensed with loss of water and ammonia to form 1, 2, 4-triazolo[4, 3-alpha]pyridin3(2H)-one, with on treatment with 1-(3-chlorophenyl)4, 3-chlorophenyl)piperazine and sodamide, yields trazodone., Impurities: ...1-(3-chloropropyl)-4-(3-chlorophenyl)piperazine HCl (CCP HCl) a process related impurity in trazodone., Genotoxic Impurity, Formulations, Preparations: Beneficat, Depyrel, Taxagon, Trazodil, AF-1161, Molipaxin, Oleptro, Thombran, Trazolan, Trittico., Trazodone hydrochloride, The main ingredient in the drug Desyrel ... (tablets), Table: Trazodone Hydrochloride Preparations [Table#6674].
Category: Organic Chemicals.
Independent reference data for Trazodone (CAS 19794-93-5), compiled from public chemistry databases.
| CAS Registry Number | 19794-93-5 |
|---|---|
| PubChem CID | 5533 |
| Molecular formula | C19H22ClN5O |
| IUPAC name | 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one |
| UNII (FDA) | YBK48BXK30 |
| Molecular Weight | 371.9 |
|---|---|
| XLogP3 | 2.8 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 5 |
| Exact Mass | 371.1512880 |
| Monoisotopic Mass | 371.1512880 |
| Topological Polar Surface Area | 42.4 |
| Heavy Atom Count | 26 |
| Boiling Point | 528.5 |
|---|---|
| Melting Point | 231-234 |
| Melting Point | 86 - 87 °C |
| Solubility | 2.90e-01 g/L |
| LogP | 2.68 |
| LogP | 2.9 |
| LogP | 2.92 |
| Ionization Efficiency | 4.22 |
| Ionization Efficiency | 2.09 |
| Ionization Efficiency | MeCN (90%) |
trazodone; 19794-93-5; Trazodon; Beneficat; Trazalon; Trazodil; Trazodona; Trazonil; Trittico; Desirel; Sideril; Trazodonum; Molipaxin; Trazodonum [Latin]; Desyrel Dividose; 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-
| Reported hazard statements | H302 (100%), H351 |
|---|
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Trazodone · CAS 19794-93-5 · C19H22ClN5O. UNII YBK48BXK30. Boiling Point: 528.5; Melting Point: 231-234; Melting Point: 86 - 87 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 曲唑酮