曲唑酮（CAS 19794-93-5）：分子式 C19H22ClN5O、分子量 371.9。
| CAS号 | 19794-93-5 |
|---|---|
| 分子式 | C19H22ClN5O |
| 分子量 | 371.9 |
| 熔点 | 231-234 |
| 沸点 | 528.5 |
| LogP | 2.68 |
| 应用领域 | Uses: Anti-Anxiety Agents、Antidepressive Agents、Second-Generation、Serotonin Uptake Inhibitors、MEDICATION、MEDICATION (VET)、Use (kg、approx.) in Germany (2009): >500、Use (kg) in USA (2002): 20900、Consumption (g per capita、approx.) in Germany (2009): 0.00611、Consumption (g per capita) in the USA (2002): 0.0741、Calculated removal (%): 7.9、For the treatment of depression.、Use Classification: Pharmaceuticals、Methods of Manufacturing: Semicarbazide and 2-chloropyridine are condensed with loss of water and ammonia to form 1、2、4-triazolo[4、3-alpha]pyridin3(2H)-one、with on treatment with 1-(3-chlorophenyl)4、3-chlorophenyl)piperazine and sodamide、yields trazodone.、Impurities: ...1-(3-chloropropyl)-4-(3-chlorophenyl)piperazine HCl (CCP HCl) a process related impurity in trazodone.、Genotoxic Impurity、Formulations、Preparations: Beneficat、Depyrel、Taxagon、Trazodil、AF-1161、Molipaxin、Oleptro、Thombran、Trazolan、Trittico.、Trazodone hydrochloride、The main ingredient in the drug Desyrel ... (tablets)、Table: Trazodone Hydrochloride Preparations [Table#6674] |
登记用途：Uses: Anti-Anxiety Agents、Antidepressive Agents、Second-Generation、Serotonin Uptake Inhibitors、MEDICATION、MEDICATION (VET)、Use (kg、approx.) in Germany (2009): >500、Use (kg) in USA (2002): 20900、Consumption (g per capita、approx.) in Germany (2009): 0.00611、Consumption (g per capita) in the USA (2002): 0.0741、Calculated removal (%): 7.9、For the treatment of depression.、Use Classification: Pharmaceuticals、Methods of Manufacturing: Semicarbazide and 2-chloropyridine are condensed with loss of water and ammonia to form 1、2、4-triazolo[4、3-alpha]pyridin3(2H)-one、with on treatment with 1-(3-chlorophenyl)4、3-chlorophenyl)piperazine and sodamide、yields trazodone.、Impurities: ...1-(3-chloropropyl)-4-(3-chlorophenyl)piperazine HCl (CCP HCl) a process related impurity in trazodone.、Genotoxic Impurity、Formulations、Preparations: Beneficat、Depyrel、Taxagon、Trazodil、AF-1161、Molipaxin、Oleptro、Thombran、Trazolan、Trittico.、Trazodone hydrochloride、The main ingredient in the drug Desyrel ... (tablets)、Table: Trazodone Hydrochloride Preparations [Table#6674]。
曲唑酮 是一种化工化合物，登记 CAS 号为 19794-93-5，分子式 C19H22ClN5O（分子量 371.9）。
登记 CAS 号：19794-93-5
其分子式 C19H22ClN5O 由 19 个碳、22 个氢、1 个氯、5 个氮、1 个氧 组成。
别名/同义词：曲唑酮 · Trazodone
曲唑酮 的 CAS 登记号为 19794-93-5。
分子式 C19H22ClN5O，分子量 371.9。
别名/同义词：曲唑酮、Trazodone。
登记用途：Uses: Anti-Anxiety Agents、Antidepressive Agents、Second-Generation、Serotonin Uptake Inhibitors、MEDICATION、MEDICATION (VET)、Use (kg、approx.) in Germany (2009): >500、Use (kg) in USA (2002): 20900、Consumption (g per capita、approx.) in Germany (2009): 0.00611、Consumption (g per capita) in the USA (2002): 0.0741、Calculated removal (%): 7.9、For the treatment of depression.、Use Classification: Pharmaceuticals、Methods of Manufacturing: Semicarbazide and 2-chloropyridine are condensed with loss of water and ammonia to form 1、2、4-triazolo[4、3-alpha]pyridin3(2H)-one、with on treatment with 1-(3-chlorophenyl)4、3-chlorophenyl)piperazine and sodamide、yields trazodone.、Impurities: ...1-(3-chloropropyl)-4-(3-chlorophenyl)piperazine HCl (CCP HCl) a process related impurity in trazodone.、Genotoxic Impurity、Formulations、Preparations: Beneficat、Depyrel、Taxagon、Trazodil、AF-1161、Molipaxin、Oleptro、Thombran、Trazolan、Trittico.、Trazodone hydrochloride、The main ingredient in the drug Desyrel ... (tablets)、Table: Trazodone Hydrochloride Preparations [Table#6674]。
曲唑酮（CAS 19794-93-5）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 19794-93-5 |
|---|---|
| PubChem CID | 5533 |
| Molecular formula | C19H22ClN5O |
| IUPAC name | 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one |
| UNII (FDA) | YBK48BXK30 |
| Molecular Weight | 371.9 |
|---|---|
| XLogP3 | 2.8 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 5 |
| Exact Mass | 371.1512880 |
| Monoisotopic Mass | 371.1512880 |
| Topological Polar Surface Area | 42.4 |
| Heavy Atom Count | 26 |
| Boiling Point | 528.5 |
|---|---|
| Melting Point | 231-234 |
| Melting Point | 86 - 87 °C |
| Solubility | 2.90e-01 g/L |
| LogP | 2.68 |
| LogP | 2.9 |
| LogP | 2.92 |
| Ionization Efficiency | 4.22 |
| Ionization Efficiency | 2.09 |
| Ionization Efficiency | MeCN (90%) |
trazodone; 19794-93-5; Trazodon; Beneficat; Trazalon; Trazodil; Trazodona; Trazonil; Trittico; Desirel; Sideril; Trazodonum; Molipaxin; Trazodonum [Latin]; Desyrel Dividose; 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-
| Reported hazard statements | H302 (100%), H351 |
|---|
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Trazodone · CAS 19794-93-5 · C19H22ClN5O. UNII YBK48BXK30. Boiling Point: 528.5; Melting Point: 231-234; Melting Point: 86 - 87 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Trazodone