Ropivacaine (CAS 84057-95-4) — formula C17H26N2O, molecular weight 274.4; category organic chemicals.
| CAS Number | 84057-95-4 |
|---|---|
| Molecular Formula | C17H26N2O |
| Molecular Weight | 274.4 |
| LogP | 2.9 |
| Applications | Uses: Use (kg, approx.) in Germany (2009): >500, Consumption (g per capita, approx.) in Germany (2009): 0.00611, Excretion rate: 0.01, Calculated removal (%): 13.5, Used in obstetric anesthesia and regional anesthesia for surgery. Ropivacaine is indicated for local anaesthesia including infiltration, nerve block, epidural and intrathecal anaesthesia in adults and children over 12 years. It is also indicated for peripheral nerve block and caudal epidural in children 1-12 years for surgical pain. It is also sometimes used for infiltration anaesthesia for surgical pain in children. |
| Category | Organic Chemicals |
Documented applications: Uses: Use (kg, approx.) in Germany (2009): >500, Consumption (g per capita, approx.) in Germany (2009): 0.00611, Excretion rate: 0.01, Calculated removal (%): 13.5, Used in obstetric anesthesia and regional anesthesia for surgery. Ropivacaine is indicated for local anaesthesia including infiltration, nerve block, epidural and intrathecal anaesthesia in adults and children over 12 years. It is also indicated for peripheral nerve block and caudal epidural in children 1-12 years for surgical pain. It is also sometimes used for infiltration anaesthesia for surgical pain in children..
Ropivacaine is a carbon-based organic compound with CAS registry number 84057-95-4 and molecular formula C17H26N2O (molecular weight 274.4), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 84057-95-4
Its molecular formula C17H26N2O comprises 17 C, 26 H, 2 N, 1 O atoms.
Also known as: Ropivacaine · 罗哌卡因
Category: organic chemicals
The CAS registry number of Ropivacaine is 84057-95-4.
Molecular formula C17H26N2O, molecular weight 274.4.
It is also registered under: Ropivacaine, 罗哌卡因.
Recorded applications: Uses: Use (kg, approx.) in Germany (2009): >500, Consumption (g per capita, approx.) in Germany (2009): 0.00611, Excretion rate: 0.01, Calculated removal (%): 13.5, Used in obstetric anesthesia and regional anesthesia for surgery. Ropivacaine is indicated for local anaesthesia including infiltration, nerve block, epidural and intrathecal anaesthesia in adults and children over 12 years. It is also indicated for peripheral nerve block and caudal epidural in children 1-12 years for surgical pain. It is also sometimes used for infiltration anaesthesia for surgical pain in children..
Category: Organic Chemicals.
Independent reference data for Ropivacaine (CAS 84057-95-4), compiled from public chemistry databases.
| CAS Registry Number | 84057-95-4 |
|---|---|
| PubChem CID | 175805 |
| Molecular formula | C17H26N2O |
| IUPAC name | (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide |
| UNII (FDA) | 7IO5LYA57N |
| Molecular Weight | 274.4 |
|---|---|
| XLogP3 | 2.9 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 4 |
| Exact Mass | 274.204513457 |
| Monoisotopic Mass | 274.204513457 |
| Topological Polar Surface Area | 32.3 |
| Heavy Atom Count | 20 |
| Solubility | 53.8 |
|---|---|
| Solubility | 2.53e-01 g/L |
| LogP | 2.9 |
| LogP | 2.89 |
| Dissociation Constants | 8.07 |
Ropivacaine; 84057-95-4; (S)-Ropivacaine; Ropivacaina; Ropivacainum; (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide; Ropivicaine; 7IO5LYA57N; TLC590; (-)-1-Propyl-2',6'-pipecoloxylidide; TLC-590; L-N-n-propylpipecolic acid-2,6-xylidide; CHEBI:8890; (S)-(-)-1-propyl-2',6'-pipecoloxylidide; DTXSID4040187; 1-propyl-2',6'-pipecoloxylidide
| Reported hazard statements | H302 (86.7%), H315 (66.7%), H319 (66.7%), H332 (60%), H412 (73.3%) |
|---|
H302 (86.7%): Harmful if swallowed [Warning Acute toxicity, oral]
H315 (66.7%): Causes skin irritation [Warning Skin corrosion/irritation]
Ropivacaine · CAS 84057-95-4 · C17H26N2O. UNII 7IO5LYA57N. Solubility: 53.8; Solubility: 2.53e-01 g/L; LogP: 2.9.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 罗哌卡因