罗哌卡因（CAS 84057-95-4）：分子式 C17H26N2O、分子量 274.4。
| CAS号 | 84057-95-4 |
|---|---|
| 分子式 | C17H26N2O |
| 分子量 | 274.4 |
| LogP | 2.9 |
| 应用领域 | Uses: Use (kg、approx.) in Germany (2009): >500、Consumption (g per capita、approx.) in Germany (2009): 0.00611、Excretion rate: 0.01、Calculated removal (%): 13.5、Used in obstetric anesthesia and regional anesthesia for surgery. Ropivacaine is indicated for local anaesthesia including infiltration、nerve block、epidural and intrathecal anaesthesia in adults and children over 12 years. It is also indicated for peripheral nerve block and caudal epidural in children 1-12 years for surgical pain. It is also sometimes used for infiltration anaesthesia for surgical pain in children. |
登记用途：Uses: Use (kg、approx.) in Germany (2009): >500、Consumption (g per capita、approx.) in Germany (2009): 0.00611、Excretion rate: 0.01、Calculated removal (%): 13.5、Used in obstetric anesthesia and regional anesthesia for surgery. Ropivacaine is indicated for local anaesthesia including infiltration、nerve block、epidural and intrathecal anaesthesia in adults and children over 12 years. It is also indicated for peripheral nerve block and caudal epidural in children 1-12 years for surgical pain. It is also sometimes used for infiltration anaesthesia for surgical pain in children.。
罗哌卡因 是一种化工化合物，登记 CAS 号为 84057-95-4，分子式 C17H26N2O（分子量 274.4）。
登记 CAS 号：84057-95-4
其分子式 C17H26N2O 由 17 个碳、26 个氢、2 个氮、1 个氧 组成。
别名/同义词：罗哌卡因 · Ropivacaine
罗哌卡因 的 CAS 登记号为 84057-95-4。
分子式 C17H26N2O，分子量 274.4。
别名/同义词：罗哌卡因、Ropivacaine。
登记用途：Uses: Use (kg、approx.) in Germany (2009): >500、Consumption (g per capita、approx.) in Germany (2009): 0.00611、Excretion rate: 0.01、Calculated removal (%): 13.5、Used in obstetric anesthesia and regional anesthesia for surgery. Ropivacaine is indicated for local anaesthesia including infiltration、nerve block、epidural and intrathecal anaesthesia in adults and children over 12 years. It is also indicated for peripheral nerve block and caudal epidural in children 1-12 years for surgical pain. It is also sometimes used for infiltration anaesthesia for surgical pain in children.。
罗哌卡因（CAS 84057-95-4）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 84057-95-4 |
|---|---|
| PubChem CID | 175805 |
| Molecular formula | C17H26N2O |
| IUPAC name | (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide |
| UNII (FDA) | 7IO5LYA57N |
| Molecular Weight | 274.4 |
|---|---|
| XLogP3 | 2.9 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 4 |
| Exact Mass | 274.204513457 |
| Monoisotopic Mass | 274.204513457 |
| Topological Polar Surface Area | 32.3 |
| Heavy Atom Count | 20 |
| Solubility | 53.8 |
|---|---|
| Solubility | 2.53e-01 g/L |
| LogP | 2.9 |
| LogP | 2.89 |
| Dissociation Constants | 8.07 |
Ropivacaine; 84057-95-4; (S)-Ropivacaine; Ropivacaina; Ropivacainum; (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide; Ropivicaine; 7IO5LYA57N; TLC590; (-)-1-Propyl-2',6'-pipecoloxylidide; TLC-590; L-N-n-propylpipecolic acid-2,6-xylidide; CHEBI:8890; (S)-(-)-1-propyl-2',6'-pipecoloxylidide; DTXSID4040187; 1-propyl-2',6'-pipecoloxylidide
| Reported hazard statements | H302 (86.7%), H315 (66.7%), H319 (66.7%), H332 (60%), H412 (73.3%) |
|---|
H302 (86.7%): Harmful if swallowed [Warning Acute toxicity, oral]
H315 (66.7%): Causes skin irritation [Warning Skin corrosion/irritation]
Ropivacaine · CAS 84057-95-4 · C17H26N2O. UNII 7IO5LYA57N. Solubility: 53.8; Solubility: 2.53e-01 g/L; LogP: 2.9.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Ropivacaine