Risedronic acid (CAS 105462-24-6) — formula C7H11NO7P2, molecular weight 283.11; category organic chemicals.
| CAS Number | 105462-24-6 |
|---|---|
| Molecular Formula | C7H11NO7P2 |
| Molecular Weight | 283.11 |
| Melting Point | 252-262 |
| Boiling Point | 692.3 |
| LogP | -3.6 |
| Applications | Uses: MEDICATION: Bone resorption inhibitor., Use (kg, approx.) in Germany (2009): >100, Use (kg) in USA (2002): 553, Consumption (g per capita, approx.) in Germany (2009): 0.00122, Consumption (g per capita) in the USA (2002): 0.00196, Calculated removal (%): 8.8, For the treatment of Paget's disease of the bone (osteitis deformans), postmenopausal and glucocorticoid-induced osteoporosis, Methods of Manufacturing: Preparation: J.J. Benedict, C. M. Perkins, EP 186405, eidem US 5583122 (1986, 1996 both to Proctor and Gamble), Formulations, Preparations: Oral: Tablets, film-coated: 5 mg Actonel, (Procter & Gamble), 30 mg Actonel, 35 mg Actonel, (Procter & Gamble)., Risedronate sodium, General Manufacturing Information: Bisphosphonate antiresorptive agent., Information available in 2005 indicated that Risedronate sodium was used in the manufacture of pharmaceutical preparations in the following countries: Algeria, Argentina, Australia, Austria, Belgium, Brazil, Canada, Chile, Colombia, Costa Rica, Czech Republic, Dominican Republic, Ecuador, El Salvador, Finland, France, Germany, Greece, Guatemala, Honduras, Hong Kong, Hungary, Indonesia, Ireland, Israel, Italy, Japan, Netherlands, Nicaragua, Norway, Panama, Poland, Portugal, Romania, Singapore, Slovenia, South Africa, Spain, Sweden, Switzerland, Thailand, Turkey, United Kingdom, United States (1, 2), Risedronate Sodium |
| Category | Organic Chemicals |
Documented applications: Uses: MEDICATION: Bone resorption inhibitor., Use (kg, approx.) in Germany (2009): >100, Use (kg) in USA (2002): 553, Consumption (g per capita, approx.) in Germany (2009): 0.00122, Consumption (g per capita) in the USA (2002): 0.00196, Calculated removal (%): 8.8, For the treatment of Paget's disease of the bone (osteitis deformans), postmenopausal and glucocorticoid-induced osteoporosis, Methods of Manufacturing: Preparation: J.J. Benedict, C. M. Perkins, EP 186405, eidem US 5583122 (1986, 1996 both to Proctor and Gamble), Formulations, Preparations: Oral: Tablets, film-coated: 5 mg Actonel, (Procter & Gamble), 30 mg Actonel, 35 mg Actonel, (Procter & Gamble)., Risedronate sodium, General Manufacturing Information: Bisphosphonate antiresorptive agent., Information available in 2005 indicated that Risedronate sodium was used in the manufacture of pharmaceutical preparations in the following countries: Algeria, Argentina, Australia, Austria, Belgium, Brazil, Canada, Chile, Colombia, Costa Rica, Czech Republic, Dominican Republic, Ecuador, El Salvador, Finland, France, Germany, Greece, Guatemala, Honduras, Hong Kong, Hungary, Indonesia, Ireland, Israel, Italy, Japan, Netherlands, Nicaragua, Norway, Panama, Poland, Portugal, Romania, Singapore, Slovenia, South Africa, Spain, Sweden, Switzerland, Thailand, Turkey, United Kingdom, United States (1, 2), Risedronate Sodium.
Risedronic acid is a carbon-based organic compound with CAS registry number 105462-24-6 and molecular formula C7H11NO7P2 (molecular weight 283.11), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 105462-24-6
Its molecular formula C7H11NO7P2 comprises 7 C, 11 H, 1 N, 7 O, 2 P atoms.
Also known as: Risedronic acid · 利塞膦酸
Category: organic chemicals
The CAS registry number of Risedronic acid is 105462-24-6.
Molecular formula C7H11NO7P2, molecular weight 283.11.
It is also registered under: Risedronic acid, 利塞膦酸.
Recorded applications: Uses: MEDICATION: Bone resorption inhibitor., Use (kg, approx.) in Germany (2009): >100, Use (kg) in USA (2002): 553, Consumption (g per capita, approx.) in Germany (2009): 0.00122, Consumption (g per capita) in the USA (2002): 0.00196, Calculated removal (%): 8.8, For the treatment of Paget's disease of the bone (osteitis deformans), postmenopausal and glucocorticoid-induced osteoporosis, Methods of Manufacturing: Preparation: J.J. Benedict, C. M. Perkins, EP 186405, eidem US 5583122 (1986, 1996 both to Proctor and Gamble), Formulations, Preparations: Oral: Tablets, film-coated: 5 mg Actonel, (Procter & Gamble), 30 mg Actonel, 35 mg Actonel, (Procter & Gamble)., Risedronate sodium, General Manufacturing Information: Bisphosphonate antiresorptive agent., Information available in 2005 indicated that Risedronate sodium was used in the manufacture of pharmaceutical preparations in the following countries: Algeria, Argentina, Australia, Austria, Belgium, Brazil, Canada, Chile, Colombia, Costa Rica, Czech Republic, Dominican Republic, Ecuador, El Salvador, Finland, France, Germany, Greece, Guatemala, Honduras, Hong Kong, Hungary, Indonesia, Ireland, Israel, Italy, Japan, Netherlands, Nicaragua, Norway, Panama, Poland, Portugal, Romania, Singapore, Slovenia, South Africa, Spain, Sweden, Switzerland, Thailand, Turkey, United Kingdom, United States (1, 2), Risedronate Sodium.
Category: Organic Chemicals.
Independent reference data for Risedronic acid (CAS 105462-24-6), compiled from public chemistry databases.
| CAS Registry Number | 105462-24-6 |
|---|---|
| PubChem CID | 5245 |
| Molecular formula | C7H11NO7P2 |
| IUPAC name | (1-hydroxy-1-phosphono-2-pyridin-3-ylethyl)phosphonic acid |
| UNII (FDA) | KM2Z91756Z |
| Molecular Weight | 283.11 |
|---|---|
| XLogP3 | -3.1 |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 4 |
| Exact Mass | 283.00107569 |
| Monoisotopic Mass | 283.00107569 |
| Topological Polar Surface Area | 148 |
| Heavy Atom Count | 17 |
| Boiling Point | 692.3 |
|---|---|
| Melting Point | 252-262 |
| Solubility | 1.04e+01 g/L |
| LogP | -3.6 |
Risedronic acid; Risedronate; 105462-24-6; Acido risedronico; Acide risedronique; Ridron; Acidum risedronicum; Phosphonic acid, [1-hydroxy-2-(3-pyridinyl)ethylidene]bis-; [1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl]phosphonic acid; M05BA07; KM2Z91756Z; Phosphonic acid, (1-hydroxy-2-(3-pyridinyl)ethylidene)bis-; DTXSID2023563; 2-(3-pyridinyl)-1-hydroxyethane diphosphonic acid; (1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl)phosphonic acid; RefChem:56783
| Reported hazard statements | H290 (50%), H302 (33.3%), H314 (66.7%), H315 (33.3%), H319 (33.3%), H335 (66.7%), H361 (50%), H362 (16.7%) |
|---|
H290 (50%): May be corrosive to metals [Warning Corrosive to Metals]
H302 (33.3%): Harmful if swallowed [Warning Acute toxicity, oral]
Risedronic acid · CAS 105462-24-6 · C7H11NO7P2. UNII KM2Z91756Z. Boiling Point: 692.3; Melting Point: 252-262; Solubility: 1.04e+01 g/L.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 利塞膦酸