利塞膦酸（CAS 105462-24-6）：分子式 C7H11NO7P2、分子量 283.11。
| CAS号 | 105462-24-6 |
|---|---|
| 分子式 | C7H11NO7P2 |
| 分子量 | 283.11 |
| 熔点 | 252-262 |
| 沸点 | 692.3 |
| LogP | -3.6 |
| 应用领域 | Uses: MEDICATION: Bone resorption inhibitor.、Use (kg、approx.) in Germany (2009): >100、Use (kg) in USA (2002): 553、Consumption (g per capita、approx.) in Germany (2009): 0.00122、Consumption (g per capita) in the USA (2002): 0.00196、Calculated removal (%): 8.8、For the treatment of Paget's disease of the bone (osteitis deformans)、postmenopausal and glucocorticoid-induced osteoporosis、Methods of Manufacturing: Preparation: J.J. Benedict、C. M. Perkins、EP 186405、eidem US 5583122 (1986、1996 both to Proctor and Gamble)、Formulations、Preparations: Oral: Tablets、film-coated: 5 mg Actonel、(Procter & Gamble)、30 mg Actonel、35 mg Actonel、(Procter & Gamble).、Risedronate sodium、General Manufacturing Information: Bisphosphonate antiresorptive agent.、Information available in 2005 indicated that Risedronate sodium was used in the manufacture of pharmaceutical preparations in the following countries: Algeria、Argentina、Australia、Austria、Belgium、Brazil、Canada、Chile、Colombia、Costa Rica、Czech Republic、Dominican Republic、Ecuador、El Salvador、Finland、France、Germany、Greece、Guatemala、Honduras、Hong Kong、Hungary、Indonesia、Ireland、Israel、Italy、Japan、Netherlands、Nicaragua、Norway、Panama、Poland、Portugal、Romania、Singapore、Slovenia、South Africa、Spain、Sweden、Switzerland、Thailand、Turkey、United Kingdom、United States (1、2)、Risedronate Sodium |
登记用途：Uses: MEDICATION: Bone resorption inhibitor.、Use (kg、approx.) in Germany (2009): >100、Use (kg) in USA (2002): 553、Consumption (g per capita、approx.) in Germany (2009): 0.00122、Consumption (g per capita) in the USA (2002): 0.00196、Calculated removal (%): 8.8、For the treatment of Paget's disease of the bone (osteitis deformans)、postmenopausal and glucocorticoid-induced osteoporosis、Methods of Manufacturing: Preparation: J.J. Benedict、C. M. Perkins、EP 186405、eidem US 5583122 (1986、1996 both to Proctor and Gamble)、Formulations、Preparations: Oral: Tablets、film-coated: 5 mg Actonel、(Procter & Gamble)、30 mg Actonel、35 mg Actonel、(Procter & Gamble).、Risedronate sodium、General Manufacturing Information: Bisphosphonate antiresorptive agent.、Information available in 2005 indicated that Risedronate sodium was used in the manufacture of pharmaceutical preparations in the following countries: Algeria、Argentina、Australia、Austria、Belgium、Brazil、Canada、Chile、Colombia、Costa Rica、Czech Republic、Dominican Republic、Ecuador、El Salvador、Finland、France、Germany、Greece、Guatemala、Honduras、Hong Kong、Hungary、Indonesia、Ireland、Israel、Italy、Japan、Netherlands、Nicaragua、Norway、Panama、Poland、Portugal、Romania、Singapore、Slovenia、South Africa、Spain、Sweden、Switzerland、Thailand、Turkey、United Kingdom、United States (1、2)、Risedronate Sodium。
利塞膦酸 是一种化工化合物，登记 CAS 号为 105462-24-6，分子式 C7H11NO7P2（分子量 283.11）。
登记 CAS 号：105462-24-6
其分子式 C7H11NO7P2 由 7 个碳、11 个氢、1 个氮、7 个氧、2 个磷 组成。
别名/同义词：利塞膦酸 · Risedronic acid
利塞膦酸 的 CAS 登记号为 105462-24-6。
分子式 C7H11NO7P2，分子量 283.11。
别名/同义词：利塞膦酸、Risedronic acid。
登记用途：Uses: MEDICATION: Bone resorption inhibitor.、Use (kg、approx.) in Germany (2009): >100、Use (kg) in USA (2002): 553、Consumption (g per capita、approx.) in Germany (2009): 0.00122、Consumption (g per capita) in the USA (2002): 0.00196、Calculated removal (%): 8.8、For the treatment of Paget's disease of the bone (osteitis deformans)、postmenopausal and glucocorticoid-induced osteoporosis、Methods of Manufacturing: Preparation: J.J. Benedict、C. M. Perkins、EP 186405、eidem US 5583122 (1986、1996 both to Proctor and Gamble)、Formulations、Preparations: Oral: Tablets、film-coated: 5 mg Actonel、(Procter & Gamble)、30 mg Actonel、35 mg Actonel、(Procter & Gamble).、Risedronate sodium、General Manufacturing Information: Bisphosphonate antiresorptive agent.、Information available in 2005 indicated that Risedronate sodium was used in the manufacture of pharmaceutical preparations in the following countries: Algeria、Argentina、Australia、Austria、Belgium、Brazil、Canada、Chile、Colombia、Costa Rica、Czech Republic、Dominican Republic、Ecuador、El Salvador、Finland、France、Germany、Greece、Guatemala、Honduras、Hong Kong、Hungary、Indonesia、Ireland、Israel、Italy、Japan、Netherlands、Nicaragua、Norway、Panama、Poland、Portugal、Romania、Singapore、Slovenia、South Africa、Spain、Sweden、Switzerland、Thailand、Turkey、United Kingdom、United States (1、2)、Risedronate Sodium。
利塞膦酸（CAS 105462-24-6）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 105462-24-6 |
|---|---|
| PubChem CID | 5245 |
| Molecular formula | C7H11NO7P2 |
| IUPAC name | (1-hydroxy-1-phosphono-2-pyridin-3-ylethyl)phosphonic acid |
| UNII (FDA) | KM2Z91756Z |
| Molecular Weight | 283.11 |
|---|---|
| XLogP3 | -3.1 |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 4 |
| Exact Mass | 283.00107569 |
| Monoisotopic Mass | 283.00107569 |
| Topological Polar Surface Area | 148 |
| Heavy Atom Count | 17 |
| Boiling Point | 692.3 |
|---|---|
| Melting Point | 252-262 |
| Solubility | 1.04e+01 g/L |
| LogP | -3.6 |
Risedronic acid; Risedronate; 105462-24-6; Acido risedronico; Acide risedronique; Ridron; Acidum risedronicum; Phosphonic acid, [1-hydroxy-2-(3-pyridinyl)ethylidene]bis-; [1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl]phosphonic acid; M05BA07; KM2Z91756Z; Phosphonic acid, (1-hydroxy-2-(3-pyridinyl)ethylidene)bis-; DTXSID2023563; 2-(3-pyridinyl)-1-hydroxyethane diphosphonic acid; (1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl)phosphonic acid; RefChem:56783
| Reported hazard statements | H290 (50%), H302 (33.3%), H314 (66.7%), H315 (33.3%), H319 (33.3%), H335 (66.7%), H361 (50%), H362 (16.7%) |
|---|
H290 (50%): May be corrosive to metals [Warning Corrosive to Metals]
H302 (33.3%): Harmful if swallowed [Warning Acute toxicity, oral]
Risedronic acid · CAS 105462-24-6 · C7H11NO7P2. UNII KM2Z91756Z. Boiling Point: 692.3; Melting Point: 252-262; Solubility: 1.04e+01 g/L.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Risedronic acid