二苯醚（CAS 101-84-8）：分子式 C12H10O、分子量 170.21；类别 食品添加剂。
| CAS号 | 101-84-8 |
|---|---|
| 分子式 | C12H10O |
| 分子量 | 170.21 |
| 熔点 | 80.3 °F (NTP, 1992) |
| 沸点 | 496.27 °F at 760 mmHg (NTP, 1992) |
| LogP | 4.2 |
| 应用领域 | Uses: Used as a heat transfer medium、Dowtherm A、and as a chemical intermediate for surface active agents and lubricants、[ACGIH]、Perfumery、particularly soaps、heat-transfer medium resins for laminated electrical insulation、chemical intermediate for such reactions as halogenation、acylation、alkylation.、Commonly used dye carrier.、From table、... Employed as a processing aid in the production of polyesters、several polybromine derivatives of diphenyl ether are used as fire retardants.、... Used in large quantities in soap perfumes. However、its main application is as a heat-transfer medium (eutectic mixture with diphenyl).、For more Uses (Complete) data for DIPHENYL ETHER (6 total)、please visit the HSDB record page.、Use Classification: Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Industry Uses: Intermediate、Fragrance、Heat transferring agent、Processing aids not otherwise specified、Surfactant (surface active agent)、Consumer Uses: Not Known or Reasonably Ascertainable、Household Products: Information on 69 consumer products that contain Diphenyl Ether in the following categories is provided:、• Auto Products、• Commercial、Institutional、• Inside the Home、Methods of Manufacturing: Prepared by heating sodium phenolate with chlorobenzene.、Reaction of bromobenzene and sodium phenate heated under pressure.、By heating potassium phenolate with bromobenzene or with chlorobenzene at elevated temperatures.、Diphenyl ether is obtained as a byproduct in the production of phenol by high-pressure hydrolysis of chlorobenzene.、Catalysis of phenol...、phenol is、heated to 350 °C in an autoclave with activated fuller's earth、Formulations、Preparations: Grades: technical、perfume、industrial.、Usual concns in final products: soap、0.05%、detergent、0.005%、creams、lotions、0.15%、Eutectic heat-transfer mixture composed of 73.5% diphenyl oxide and 26.5% biphenyl...marketed under product names Dowtherm A (Dow Chemical)、Therminol VP-1 (Monsanto)、Thermex (Imperial Chem)、Therm S-300 (Nippon Steel Chemical)、Diphyl (Bayer)、and Gilotherm (Progil)、Consumption Patterns: Approximately 67% is used in making heat-transfer fluids、approximately 100、000 lbs used annually in fragrance products、U.S. Production: 2023: 40、000、000 - <55、000 lb、2022: 70、000 - <85、2021: 70、2020: 70、(1972) OVER 4.54X10+5 G、(1975) PROBABLY GREATER THAN 4.54X10+5 G、Benzene、1、1'-oxybis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: Benzene、1'-oxybis-. Aggregated National Production Volume: 50 to < 100 million pounds.、Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Benzene、1'-oxybis-. National Production Volume: 77、839、277 lb、yr.、U.S. Imports: (1972) 2.74X10+6 G、(1975) 9.17X10+7 G、581、836 lbs (principal US custom districts)、General Manufacturing Information: Synthetic Dye and Pigment Manufacturing、Not Known or Reasonably Ascertainable、All Other Chemical Product and Preparation Manufacturing、Petrochemical Manufacturing、All Other Basic Organic Chemical Manufacturing、Soap、Cleaning Compound、and Toilet Preparation Manufacturing、1'-oxybis-: ACTIVE |
| 类别 | 抗氧化剂 |
登记用途：Uses: Used as a heat transfer medium、Dowtherm A、and as a chemical intermediate for surface active agents and lubricants、[ACGIH]、Perfumery、particularly soaps、heat-transfer medium resins for laminated electrical insulation、chemical intermediate for such reactions as halogenation、acylation、alkylation.、Commonly used dye carrier.、From table、... Employed as a processing aid in the production of polyesters、several polybromine derivatives of diphenyl ether are used as fire retardants.、... Used in large quantities in soap perfumes. However、its main application is as a heat-transfer medium (eutectic mixture with diphenyl).、For more Uses (Complete) data for DIPHENYL ETHER (6 total)、please visit the HSDB record page.、Use Classification: Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Industry Uses: Intermediate、Fragrance、Heat transferring agent、Processing aids not otherwise specified、Surfactant (surface active agent)、Consumer Uses: Not Known or Reasonably Ascertainable、Household Products: Information on 69 consumer products that contain Diphenyl Ether in the following categories is provided:、• Auto Products、• Commercial、Institutional、• Inside the Home、Methods of Manufacturing: Prepared by heating sodium phenolate with chlorobenzene.、Reaction of bromobenzene and sodium phenate heated under pressure.、By heating potassium phenolate with bromobenzene or with chlorobenzene at elevated temperatures.、Diphenyl ether is obtained as a byproduct in the production of phenol by high-pressure hydrolysis of chlorobenzene.、Catalysis of phenol...、phenol is、heated to 350 °C in an autoclave with activated fuller's earth、Formulations、Preparations: Grades: technical、perfume、industrial.、Usual concns in final products: soap、0.05%、detergent、0.005%、creams、lotions、0.15%、Eutectic heat-transfer mixture composed of 73.5% diphenyl oxide and 26.5% biphenyl...marketed under product names Dowtherm A (Dow Chemical)、Therminol VP-1 (Monsanto)、Thermex (Imperial Chem)、Therm S-300 (Nippon Steel Chemical)、Diphyl (Bayer)、and Gilotherm (Progil)、Consumption Patterns: Approximately 67% is used in making heat-transfer fluids、approximately 100、000 lbs used annually in fragrance products、U.S. Production: 2023: 40、000、000 - <55、000 lb、2022: 70、000 - <85、2021: 70、2020: 70、(1972) OVER 4.54X10+5 G、(1975) PROBABLY GREATER THAN 4.54X10+5 G、Benzene、1、1'-oxybis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: Benzene、1'-oxybis-. Aggregated National Production Volume: 50 to < 100 million pounds.、Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Benzene、1'-oxybis-. National Production Volume: 77、839、277 lb、yr.、U.S. Imports: (1972) 2.74X10+6 G、(1975) 9.17X10+7 G、581、836 lbs (principal US custom districts)、General Manufacturing Information: Synthetic Dye and Pigment Manufacturing、Not Known or Reasonably Ascertainable、All Other Chemical Product and Preparation Manufacturing、Petrochemical Manufacturing、All Other Basic Organic Chemical Manufacturing、Soap、Cleaning Compound、and Toilet Preparation Manufacturing、1'-oxybis-: ACTIVE。
二苯醚 是一种食品级化合物，登记 CAS 号为 101-84-8，分子式 C12H10O（分子量 170.21），归属于食品添加剂大类化工原料。
登记 CAS 号：101-84-8
其分子式 C12H10O 由 12 个碳、10 个氢、1 个氧 组成。
别名/同义词：二苯醚 · Phenyl ether
所属分类：食品添加剂
二苯醚 的 CAS 登记号为 101-84-8。
分子式 C12H10O，分子量 170.21。
别名/同义词：二苯醚、Phenyl ether。
登记用途：Uses: Used as a heat transfer medium、Dowtherm A、and as a chemical intermediate for surface active agents and lubricants、[ACGIH]、Perfumery、particularly soaps、heat-transfer medium resins for laminated electrical insulation、chemical intermediate for such reactions as halogenation、acylation、alkylation.、Commonly used dye carrier.、From table、... Employed as a processing aid in the production of polyesters、several polybromine derivatives of diphenyl ether are used as fire retardants.、... Used in large quantities in soap perfumes. However、its main application is as a heat-transfer medium (eutectic mixture with diphenyl).、For more Uses (Complete) data for DIPHENYL ETHER (6 total)、please visit the HSDB record page.、Use Classification: Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Industry Uses: Intermediate、Fragrance、Heat transferring agent、Processing aids not otherwise specified、Surfactant (surface active agent)、Consumer Uses: Not Known or Reasonably Ascertainable、Household Products: Information on 69 consumer products that contain Diphenyl Ether in the following categories is provided:、• Auto Products、• Commercial、Institutional、• Inside the Home、Methods of Manufacturing: Prepared by heating sodium phenolate with chlorobenzene.、Reaction of bromobenzene and sodium phenate heated under pressure.、By heating potassium phenolate with bromobenzene or with chlorobenzene at elevated temperatures.、Diphenyl ether is obtained as a byproduct in the production of phenol by high-pressure hydrolysis of chlorobenzene.、Catalysis of phenol...、phenol is、heated to 350 °C in an autoclave with activated fuller's earth、Formulations、Preparations: Grades: technical、perfume、industrial.、Usual concns in final products: soap、0.05%、detergent、0.005%、creams、lotions、0.15%、Eutectic heat-transfer mixture composed of 73.5% diphenyl oxide and 26.5% biphenyl...marketed under product names Dowtherm A (Dow Chemical)、Therminol VP-1 (Monsanto)、Thermex (Imperial Chem)、Therm S-300 (Nippon Steel Chemical)、Diphyl (Bayer)、and Gilotherm (Progil)、Consumption Patterns: Approximately 67% is used in making heat-transfer fluids、approximately 100、000 lbs used annually in fragrance products、U.S. Production: 2023: 40、000、000 - <55、000 lb、2022: 70、000 - <85、2021: 70、2020: 70、(1972) OVER 4.54X10+5 G、(1975) PROBABLY GREATER THAN 4.54X10+5 G、Benzene、1、1'-oxybis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: Benzene、1'-oxybis-. Aggregated National Production Volume: 50 to < 100 million pounds.、Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Benzene、1'-oxybis-. National Production Volume: 77、839、277 lb、yr.、U.S. Imports: (1972) 2.74X10+6 G、(1975) 9.17X10+7 G、581、836 lbs (principal US custom districts)、General Manufacturing Information: Synthetic Dye and Pigment Manufacturing、Not Known or Reasonably Ascertainable、All Other Chemical Product and Preparation Manufacturing、Petrochemical Manufacturing、All Other Basic Organic Chemical Manufacturing、Soap、Cleaning Compound、and Toilet Preparation Manufacturing、1'-oxybis-: ACTIVE。
所属分类：抗氧化剂。
二苯醚（CAS 101-84-8）的独立参考数据，整理自公开化学数据库。
| CAS 号 | 101-84-8 |
|---|---|
| PubChem CID | 7583 |
| 分子式 | C12H10O |
| 分子量 | 170.07 g/mol |
| IUPAC 名称 | phenoxybenzene |
| InChIKey | USIUVYZYUHIAEV-UHFFFAOYSA-N |
| UNII（FDA） | 3O695R5M1U |
| ChEBI 编号 | CHEBI:39258 |
| FEMA 编号 | 3667 |
| JECFA 编号 | 1255 |
| Molecular Weight | 170.21 |
|---|---|
| XLogP3 | 4.2 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 2 |
| Exact Mass | 170.073164938 |
| Monoisotopic Mass | 170.073164938 |
| Topological Polar Surface Area | 9.2 |
| Heavy Atom Count | 13 |
| Boiling Point | 496.27 °F at 760 mmHg (NTP, 1992) |
|---|---|
| Boiling Point | 258 °C |
| Boiling Point | 258.00 to 259.00 °C. @ 760.00 mm Hg |
| Boiling Point | 257 °C |
| Boiling Point | 259 °C |
| Boiling Point | 498 °F |
| Boiling Point | 259 °C @760 [mm Hg] |
| Melting Point | 80.3 °F (NTP, 1992) |
| Melting Point | 26.865 °C |
| Melting Point | 37 - 39 °C |
DIPHENYL ETHER; Diphenyl oxide; 101-84-8; Phenoxybenzene; Phenyl ether; Benzene, 1,1'-oxybis-; Diphenylether; Oxybisbenzene; Phenyl oxide; Biphenyl oxide; Geranium crystals; Oxydiphenyl; Chemcryl JK-EB; Benzene, phenoxy-; 1,1'-Oxybis(benzene); 1,1'-Oxybisbenzene
| 法规与食品接触 | EU Flavoring substances FDA Substance added to food: FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT Flavoring Agents FLAVOURING_AGENT: Flavouring Agent Green No safety concern at current levels of intake when used as a flavouring agent |
|---|---|
| GHS 通报统计 | 0.5% (12 / 2199) |
| GHS 通报统计 | 0.5% (12 / 2199) |
|---|---|
| 已通报的危害声明 | H319 (84.8%), H400 (16.1%), H410 (10.3%), H411 (78.8%), H315, H335, H360, H372 |
二苯醚 的 CAS 号为 101-84-8，分子式 C12H10O，分子量 170.07 g/mol。 UNII 3O695R5M1U; ChEBI 39258; InChIKey USIUVYZYUHIAEV-UHFFFAOYSA-N. Boiling Point: 496.27 °F at 760 mmHg (NTP, 1992); Boiling Point: 258 °C; Boiling Point: 258.00 to 259.00 °C. @ 760.00 mm Hg.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Phenyl ether