Phenyl ether (CAS 101-84-8) — formula C12H10O, molecular weight 170.07 g/mol; category food additives.
| CAS Number | 101-84-8 |
|---|---|
| Molecular Formula | C12H10O |
| Molecular Weight | 170.07 g/mol |
| Melting Point | 80.3 °F (NTP, 1992) |
| Boiling Point | 496.27 °F at 760 mmHg (NTP, 1992) |
| LogP | 4.2 |
| Applications | Uses: Used as a heat transfer medium, Dowtherm A, and as a chemical intermediate for surface active agents and lubricants, [ACGIH], Perfumery, particularly soaps, heat-transfer medium resins for laminated electrical insulation, chemical intermediate for such reactions as halogenation, acylation, alkylation., Commonly used dye carrier., From table, ... Employed as a processing aid in the production of polyesters, several polybromine derivatives of diphenyl ether are used as fire retardants., ... Used in large quantities in soap perfumes. However, its main application is as a heat-transfer medium (eutectic mixture with diphenyl)., For more Uses (Complete) data for DIPHENYL ETHER (6 total), please visit the HSDB record page., Use Classification: Fragrance Ingredients, Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Flavoring Agents -> JECFA Flavorings Index, Industry Uses: Intermediate, Fragrance, Heat transferring agent, Processing aids not otherwise specified, Surfactant (surface active agent), Consumer Uses: Not Known or Reasonably Ascertainable, Household Products: Information on 69 consumer products that contain Diphenyl Ether in the following categories is provided:, • Auto Products, • Commercial, Institutional, • Inside the Home, Methods of Manufacturing: Prepared by heating sodium phenolate with chlorobenzene., Reaction of bromobenzene and sodium phenate heated under pressure., By heating potassium phenolate with bromobenzene or with chlorobenzene at elevated temperatures., Diphenyl ether is obtained as a byproduct in the production of phenol by high-pressure hydrolysis of chlorobenzene., Catalysis of phenol..., phenol is, heated to 350 °C in an autoclave with activated fuller's earth, Formulations, Preparations: Grades: technical, perfume, industrial., Usual concns in final products: soap, 0.05%, detergent, 0.005%, creams, lotions, 0.15%, Eutectic heat-transfer mixture composed of 73.5% diphenyl oxide and 26.5% biphenyl...marketed under product names Dowtherm A (Dow Chemical), Therminol VP-1 (Monsanto), Thermex (Imperial Chem), Therm S-300 (Nippon Steel Chemical), Diphyl (Bayer), and Gilotherm (Progil), Consumption Patterns: Approximately 67% is used in making heat-transfer fluids, approximately 100, 000 lbs used annually in fragrance products, U.S. Production: 2023: 40, 000, 000 - <55, 000 lb, 2022: 70, 000 - <85, 2021: 70, 2020: 70, (1972) OVER 4.54X10+5 G, (1975) PROBABLY GREATER THAN 4.54X10+5 G, Benzene, 1, 1'-oxybis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: Benzene, 1'-oxybis-. Aggregated National Production Volume: 50 to < 100 million pounds., Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Benzene, 1'-oxybis-. National Production Volume: 77, 839, 277 lb, yr., U.S. Imports: (1972) 2.74X10+6 G, (1975) 9.17X10+7 G, 581, 836 lbs (principal US custom districts), General Manufacturing Information: Synthetic Dye and Pigment Manufacturing, Not Known or Reasonably Ascertainable, All Other Chemical Product and Preparation Manufacturing, Petrochemical Manufacturing, All Other Basic Organic Chemical Manufacturing, Soap, Cleaning Compound, and Toilet Preparation Manufacturing, 1'-oxybis-: ACTIVE |
| Category | Antioxidants |
Documented applications: Uses: Used as a heat transfer medium, Dowtherm A, and as a chemical intermediate for surface active agents and lubricants, [ACGIH], Perfumery, particularly soaps, heat-transfer medium resins for laminated electrical insulation, chemical intermediate for such reactions as halogenation, acylation, alkylation., Commonly used dye carrier., From table, ... Employed as a processing aid in the production of polyesters, several polybromine derivatives of diphenyl ether are used as fire retardants., ... Used in large quantities in soap perfumes. However, its main application is as a heat-transfer medium (eutectic mixture with diphenyl)., For more Uses (Complete) data for DIPHENYL ETHER (6 total), please visit the HSDB record page., Use Classification: Fragrance Ingredients, Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Flavoring Agents -> JECFA Flavorings Index, Industry Uses: Intermediate, Fragrance, Heat transferring agent, Processing aids not otherwise specified, Surfactant (surface active agent), Consumer Uses: Not Known or Reasonably Ascertainable, Household Products: Information on 69 consumer products that contain Diphenyl Ether in the following categories is provided:, • Auto Products, • Commercial, Institutional, • Inside the Home, Methods of Manufacturing: Prepared by heating sodium phenolate with chlorobenzene., Reaction of bromobenzene and sodium phenate heated under pressure., By heating potassium phenolate with bromobenzene or with chlorobenzene at elevated temperatures., Diphenyl ether is obtained as a byproduct in the production of phenol by high-pressure hydrolysis of chlorobenzene., Catalysis of phenol..., phenol is, heated to 350 °C in an autoclave with activated fuller's earth, Formulations, Preparations: Grades: technical, perfume, industrial., Usual concns in final products: soap, 0.05%, detergent, 0.005%, creams, lotions, 0.15%, Eutectic heat-transfer mixture composed of 73.5% diphenyl oxide and 26.5% biphenyl...marketed under product names Dowtherm A (Dow Chemical), Therminol VP-1 (Monsanto), Thermex (Imperial Chem), Therm S-300 (Nippon Steel Chemical), Diphyl (Bayer), and Gilotherm (Progil), Consumption Patterns: Approximately 67% is used in making heat-transfer fluids, approximately 100, 000 lbs used annually in fragrance products, U.S. Production: 2023: 40, 000, 000 - <55, 000 lb, 2022: 70, 000 - <85, 2021: 70, 2020: 70, (1972) OVER 4.54X10+5 G, (1975) PROBABLY GREATER THAN 4.54X10+5 G, Benzene, 1, 1'-oxybis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: Benzene, 1'-oxybis-. Aggregated National Production Volume: 50 to < 100 million pounds., Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Benzene, 1'-oxybis-. National Production Volume: 77, 839, 277 lb, yr., U.S. Imports: (1972) 2.74X10+6 G, (1975) 9.17X10+7 G, 581, 836 lbs (principal US custom districts), General Manufacturing Information: Synthetic Dye and Pigment Manufacturing, Not Known or Reasonably Ascertainable, All Other Chemical Product and Preparation Manufacturing, Petrochemical Manufacturing, All Other Basic Organic Chemical Manufacturing, Soap, Cleaning Compound, and Toilet Preparation Manufacturing, 1'-oxybis-: ACTIVE.
Phenyl ether is a food-grade compound with CAS registry number 101-84-8 and molecular formula C12H10O (molecular weight 170.07 g/mol), belonging to the food additives segment of chemical raw materials.
CAS number: 101-84-8
Its molecular formula C12H10O comprises 12 C, 10 H, 1 O atoms.
Also known as: Phenyl ether · 二苯醚
Category: food additives
The CAS registry number of Phenyl ether is 101-84-8.
Molecular formula C12H10O, molecular weight 170.07 g/mol.
It is also registered under: Phenyl ether, 二苯醚.
Recorded applications: Uses: Used as a heat transfer medium, Dowtherm A, and as a chemical intermediate for surface active agents and lubricants, [ACGIH], Perfumery, particularly soaps, heat-transfer medium resins for laminated electrical insulation, chemical intermediate for such reactions as halogenation, acylation, alkylation., Commonly used dye carrier., From table, ... Employed as a processing aid in the production of polyesters, several polybromine derivatives of diphenyl ether are used as fire retardants., ... Used in large quantities in soap perfumes. However, its main application is as a heat-transfer medium (eutectic mixture with diphenyl)., For more Uses (Complete) data for DIPHENYL ETHER (6 total), please visit the HSDB record page., Use Classification: Fragrance Ingredients, Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Flavoring Agents -> JECFA Flavorings Index, Industry Uses: Intermediate, Fragrance, Heat transferring agent, Processing aids not otherwise specified, Surfactant (surface active agent), Consumer Uses: Not Known or Reasonably Ascertainable, Household Products: Information on 69 consumer products that contain Diphenyl Ether in the following categories is provided:, • Auto Products, • Commercial, Institutional, • Inside the Home, Methods of Manufacturing: Prepared by heating sodium phenolate with chlorobenzene., Reaction of bromobenzene and sodium phenate heated under pressure., By heating potassium phenolate with bromobenzene or with chlorobenzene at elevated temperatures., Diphenyl ether is obtained as a byproduct in the production of phenol by high-pressure hydrolysis of chlorobenzene., Catalysis of phenol..., phenol is, heated to 350 °C in an autoclave with activated fuller's earth, Formulations, Preparations: Grades: technical, perfume, industrial., Usual concns in final products: soap, 0.05%, detergent, 0.005%, creams, lotions, 0.15%, Eutectic heat-transfer mixture composed of 73.5% diphenyl oxide and 26.5% biphenyl...marketed under product names Dowtherm A (Dow Chemical), Therminol VP-1 (Monsanto), Thermex (Imperial Chem), Therm S-300 (Nippon Steel Chemical), Diphyl (Bayer), and Gilotherm (Progil), Consumption Patterns: Approximately 67% is used in making heat-transfer fluids, approximately 100, 000 lbs used annually in fragrance products, U.S. Production: 2023: 40, 000, 000 - <55, 000 lb, 2022: 70, 000 - <85, 2021: 70, 2020: 70, (1972) OVER 4.54X10+5 G, (1975) PROBABLY GREATER THAN 4.54X10+5 G, Benzene, 1, 1'-oxybis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: Benzene, 1'-oxybis-. Aggregated National Production Volume: 50 to < 100 million pounds., Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Benzene, 1'-oxybis-. National Production Volume: 77, 839, 277 lb, yr., U.S. Imports: (1972) 2.74X10+6 G, (1975) 9.17X10+7 G, 581, 836 lbs (principal US custom districts), General Manufacturing Information: Synthetic Dye and Pigment Manufacturing, Not Known or Reasonably Ascertainable, All Other Chemical Product and Preparation Manufacturing, Petrochemical Manufacturing, All Other Basic Organic Chemical Manufacturing, Soap, Cleaning Compound, and Toilet Preparation Manufacturing, 1'-oxybis-: ACTIVE.
Category: Antioxidants.
Independent reference data for Phenyl ether (CAS 101-84-8), compiled from public chemistry databases.
| CAS 号 | 101-84-8 |
|---|---|
| PubChem CID | 7583 |
| 分子式 | C12H10O |
| 分子量 | 170.07 g/mol |
| IUPAC 名称 | phenoxybenzene |
| InChIKey | USIUVYZYUHIAEV-UHFFFAOYSA-N |
| UNII（FDA） | 3O695R5M1U |
| ChEBI 编号 | CHEBI:39258 |
| FEMA 编号 | 3667 |
| JECFA 编号 | 1255 |
| Molecular Weight | 170.21 |
|---|---|
| XLogP3 | 4.2 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 2 |
| Exact Mass | 170.073164938 |
| Monoisotopic Mass | 170.073164938 |
| Topological Polar Surface Area | 9.2 |
| Heavy Atom Count | 13 |
| Boiling Point | 496.27 °F at 760 mmHg (NTP, 1992) |
|---|---|
| Boiling Point | 258 °C |
| Boiling Point | 258.00 to 259.00 °C. @ 760.00 mm Hg |
| Boiling Point | 257 °C |
| Boiling Point | 259 °C |
| Boiling Point | 498 °F |
| Boiling Point | 259 °C @760 [mm Hg] |
| Melting Point | 80.3 °F (NTP, 1992) |
| Melting Point | 26.865 °C |
| Melting Point | 37 - 39 °C |
DIPHENYL ETHER; Diphenyl oxide; 101-84-8; Phenoxybenzene; Phenyl ether; Benzene, 1,1'-oxybis-; Diphenylether; Oxybisbenzene; Phenyl oxide; Biphenyl oxide; Geranium crystals; Oxydiphenyl; Chemcryl JK-EB; Benzene, phenoxy-; 1,1'-Oxybis(benzene); 1,1'-Oxybisbenzene
| 法规与食品接触 | EU Flavoring substances FDA Substance added to food: FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT Flavoring Agents FLAVOURING_AGENT: Flavouring Agent Green No safety concern at current levels of intake when used as a flavouring agent |
|---|---|
| GHS 通报统计 | 0.5% (12 / 2199) |
| GHS 通报统计 | 0.5% (12 / 2199) |
|---|---|
| 已通报的危害声明 | H319 (84.8%), H400 (16.1%), H410 (10.3%), H411 (78.8%), H315, H335, H360, H372 |
二苯醚 的 CAS 号为 101-84-8，分子式 C12H10O，分子量 170.07 g/mol。 UNII 3O695R5M1U; ChEBI 39258; InChIKey USIUVYZYUHIAEV-UHFFFAOYSA-N. Boiling Point: 496.27 °F at 760 mmHg (NTP, 1992); Boiling Point: 258 °C; Boiling Point: 258.00 to 259.00 °C. @ 760.00 mm Hg.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 二苯醚