L-Cystein (CAS 52-90-4) — formula C3H7NO2S, molecular weight 121.16; category organic chemicals.
| CAS Number | 52-90-4 |
|---|---|
| Molecular Formula | C3H7NO2S |
| Molecular Weight | 121.16 |
| Melting Point | 240 |
| LogP | -2.49 |
| Applications | Uses: CIR ingredient: Cysteine, Cysteine is a non-essential amino acid that has been used as a dough conditioner and veterinary detoxicant, [Merck Index] Used as a flavoring agent, dough strengthener, nutritional supplement, and flour treating agent for foods, [FDA] Used for biochemical and nutritional research and as a medication, [HSDB], Reported uses (ppm):, Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association, 1994) [Table#3867], Biochemical and nutrition research, reducing agent in bread doughs (up to 90 ppm)., MEDICATION, MEDICATION (VET), Treatment with cysteine reduced seedling injury caused by gamma-irradiation of sorghum seed. Cysteine effects were most pronounced in primary root elongation., Use (kg) in Switzerland (2009): >10000, Use (kg, approx.) in Germany (2009): >100000, exact) in Germany (2009): 132069, Use (kg) in France (2004): 96759, Consumption (g per capita) in Switzerland (2009): 1.3, Consumption (g per capita, approx.) in Germany (2009): 1.2, exact) in Germany (2009): 1.6, Consumption (g per capita) in France (2004): 1.6, Excretion rate: 0.3, Calculated removal (%): 92.1, For the prevention of liver damage and kidney damage associated with overdoses of acetaminophen, Use Classification: Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Flavoring Agents -> JECFA Flavorings Index, Cosmetics -> Reducing, Antistatic, Antioxidant, Hair conditioning, Household Products: Information on 4 consumer products that contain Cysteine in the following categories is provided:, • Personal Care, Methods of Manufacturing: By addition of a thiol compound to an unsaturated amino acid derivative, by hydrolysis of proteins in the presence of carbon dioxide, by treating in HCl hydrolysis of proteins in the presence of carbon dioxide, by treating an HCl hydrolysate of hair with CuO2, followed by the decomposition of the resulting copper-cysteine complex with hydrogen sulfide, by the addition of thioacetic acid to alpha-acetamido acrylic acid, by treatment of a keratine HCl hydrolysate with zinc to reduce the cystine present to cysteine, by electrolytic reduction of cystine., L-Cysteine used to be produced almost exclusively by hydrolysis of hair or other keratins. The amino acid isolated was l-cystine, which was reduced electrolytically to l-cysteine. L-Cysteine has also been prepared from beta-chloro-d, l-alanine and sodium sulfide with cysteine desulfhydrase, an enzyme obtained from, e.g., Citrobacterium freundii. Today, however, the main processes for cysteine production are biological. A direct fermentation process has been developed for the manufacture of l-cystine, using a modified Escherichia coli bacterium. The technology has been extended to prepare other modified l-cysteine analogues. An enzymatic process for l-cysteine has been successfully developed using microorganisms capable to hydrolyze 2-amino-delta2-thiazoline 4-carboxylic acid (ATC) which is readily available from methyl alpha-chloroacrylate and thiourea. A mutant of Pseudomonas thiazolinophilum converts d, l-ATC to l-cysteine in 95% molar yield at product concentrations higher than 30 g, L., Formulations, Preparations: Available commercially as L(+)-cysteine hydrochloride., U.S. Production: Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: L-Cysteine. National Production Volume: 28, 660 lb, yr., General Manufacturing Information: L-Cysteine: ACTIVE, A non-essential amino acid in human development., An amino acid derived from cystine, occurring naturally in the L-form ... |
| Category | Organic Chemicals |
Documented applications: Uses: CIR ingredient: Cysteine, Cysteine is a non-essential amino acid that has been used as a dough conditioner and veterinary detoxicant, [Merck Index] Used as a flavoring agent, dough strengthener, nutritional supplement, and flour treating agent for foods, [FDA] Used for biochemical and nutritional research and as a medication, [HSDB], Reported uses (ppm):, Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association, 1994) [Table#3867], Biochemical and nutrition research, reducing agent in bread doughs (up to 90 ppm)., MEDICATION, MEDICATION (VET), Treatment with cysteine reduced seedling injury caused by gamma-irradiation of sorghum seed. Cysteine effects were most pronounced in primary root elongation., Use (kg) in Switzerland (2009): >10000, Use (kg, approx.) in Germany (2009): >100000, exact) in Germany (2009): 132069, Use (kg) in France (2004): 96759, Consumption (g per capita) in Switzerland (2009): 1.3, Consumption (g per capita, approx.) in Germany (2009): 1.2, exact) in Germany (2009): 1.6, Consumption (g per capita) in France (2004): 1.6, Excretion rate: 0.3, Calculated removal (%): 92.1, For the prevention of liver damage and kidney damage associated with overdoses of acetaminophen, Use Classification: Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Flavoring Agents -> JECFA Flavorings Index, Cosmetics -> Reducing, Antistatic, Antioxidant, Hair conditioning, Household Products: Information on 4 consumer products that contain Cysteine in the following categories is provided:, • Personal Care, Methods of Manufacturing: By addition of a thiol compound to an unsaturated amino acid derivative, by hydrolysis of proteins in the presence of carbon dioxide, by treating in HCl hydrolysis of proteins in the presence of carbon dioxide, by treating an HCl hydrolysate of hair with CuO2, followed by the decomposition of the resulting copper-cysteine complex with hydrogen sulfide, by the addition of thioacetic acid to alpha-acetamido acrylic acid, by treatment of a keratine HCl hydrolysate with zinc to reduce the cystine present to cysteine, by electrolytic reduction of cystine., L-Cysteine used to be produced almost exclusively by hydrolysis of hair or other keratins. The amino acid isolated was l-cystine, which was reduced electrolytically to l-cysteine. L-Cysteine has also been prepared from beta-chloro-d, l-alanine and sodium sulfide with cysteine desulfhydrase, an enzyme obtained from, e.g., Citrobacterium freundii. Today, however, the main processes for cysteine production are biological. A direct fermentation process has been developed for the manufacture of l-cystine, using a modified Escherichia coli bacterium. The technology has been extended to prepare other modified l-cysteine analogues. An enzymatic process for l-cysteine has been successfully developed using microorganisms capable to hydrolyze 2-amino-delta2-thiazoline 4-carboxylic acid (ATC) which is readily available from methyl alpha-chloroacrylate and thiourea. A mutant of Pseudomonas thiazolinophilum converts d, l-ATC to l-cysteine in 95% molar yield at product concentrations higher than 30 g, L., Formulations, Preparations: Available commercially as L(+)-cysteine hydrochloride., U.S. Production: Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: L-Cysteine. National Production Volume: 28, 660 lb, yr., General Manufacturing Information: L-Cysteine: ACTIVE, A non-essential amino acid in human development., An amino acid derived from cystine, occurring naturally in the L-form ....
L-Cystein is a carbon-based organic compound with CAS registry number 52-90-4 and molecular formula C3H7NO2S (molecular weight 121.16), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 52-90-4
Its molecular formula C3H7NO2S comprises 3 C, 7 H, 1 N, 2 O, 1 S atoms.
Also known as: L-Cystein · L-半胱氨酸
Category: organic chemicals
The CAS registry number of L-Cystein is 52-90-4.
Molecular formula C3H7NO2S, molecular weight 121.16.
It is also registered under: L-Cystein, L-半胱氨酸.
Recorded applications: Uses: CIR ingredient: Cysteine, Cysteine is a non-essential amino acid that has been used as a dough conditioner and veterinary detoxicant, [Merck Index] Used as a flavoring agent, dough strengthener, nutritional supplement, and flour treating agent for foods, [FDA] Used for biochemical and nutritional research and as a medication, [HSDB], Reported uses (ppm):, Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association, 1994) [Table#3867], Biochemical and nutrition research, reducing agent in bread doughs (up to 90 ppm)., MEDICATION, MEDICATION (VET), Treatment with cysteine reduced seedling injury caused by gamma-irradiation of sorghum seed. Cysteine effects were most pronounced in primary root elongation., Use (kg) in Switzerland (2009): >10000, Use (kg, approx.) in Germany (2009): >100000, exact) in Germany (2009): 132069, Use (kg) in France (2004): 96759, Consumption (g per capita) in Switzerland (2009): 1.3, Consumption (g per capita, approx.) in Germany (2009): 1.2, exact) in Germany (2009): 1.6, Consumption (g per capita) in France (2004): 1.6, Excretion rate: 0.3, Calculated removal (%): 92.1, For the prevention of liver damage and kidney damage associated with overdoses of acetaminophen, Use Classification: Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Flavoring Agents -> JECFA Flavorings Index, Cosmetics -> Reducing, Antistatic, Antioxidant, Hair conditioning, Household Products: Information on 4 consumer products that contain Cysteine in the following categories is provided:, • Personal Care, Methods of Manufacturing: By addition of a thiol compound to an unsaturated amino acid derivative, by hydrolysis of proteins in the presence of carbon dioxide, by treating in HCl hydrolysis of proteins in the presence of carbon dioxide, by treating an HCl hydrolysate of hair with CuO2, followed by the decomposition of the resulting copper-cysteine complex with hydrogen sulfide, by the addition of thioacetic acid to alpha-acetamido acrylic acid, by treatment of a keratine HCl hydrolysate with zinc to reduce the cystine present to cysteine, by electrolytic reduction of cystine., L-Cysteine used to be produced almost exclusively by hydrolysis of hair or other keratins. The amino acid isolated was l-cystine, which was reduced electrolytically to l-cysteine. L-Cysteine has also been prepared from beta-chloro-d, l-alanine and sodium sulfide with cysteine desulfhydrase, an enzyme obtained from, e.g., Citrobacterium freundii. Today, however, the main processes for cysteine production are biological. A direct fermentation process has been developed for the manufacture of l-cystine, using a modified Escherichia coli bacterium. The technology has been extended to prepare other modified l-cysteine analogues. An enzymatic process for l-cysteine has been successfully developed using microorganisms capable to hydrolyze 2-amino-delta2-thiazoline 4-carboxylic acid (ATC) which is readily available from methyl alpha-chloroacrylate and thiourea. A mutant of Pseudomonas thiazolinophilum converts d, l-ATC to l-cysteine in 95% molar yield at product concentrations higher than 30 g, L., Formulations, Preparations: Available commercially as L(+)-cysteine hydrochloride., U.S. Production: Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: L-Cysteine. National Production Volume: 28, 660 lb, yr., General Manufacturing Information: L-Cysteine: ACTIVE, A non-essential amino acid in human development., An amino acid derived from cystine, occurring naturally in the L-form ....
Category: Organic Chemicals.
Independent reference data for L-Cystein (CAS 52-90-4), compiled from public chemistry databases.
| CAS Registry Number | 52-90-4 |
|---|---|
| PubChem CID | 5862 |
| Molecular formula | C3H7NO2S |
| IUPAC name | (2R)-2-amino-3-sulfanylpropanoic acid |
| UNII (FDA) | K848JZ4886 |
| FEMA number | 3263 |
| JECFA number | 1419 |
| Molecular Weight | 121.16 |
|---|---|
| XLogP3 | -2.5 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 2 |
| Exact Mass | 121.01974964 |
| Monoisotopic Mass | 121.01974964 |
| Topological Polar Surface Area | 64.3 |
| Heavy Atom Count | 7 |
| Melting Point | 240 |
|---|---|
| Melting Point | 260 °C decomposes |
| Melting Point | 220 °C |
| Solubility | 277000 |
| Solubility | 277 mg/mL at 25 °C |
| Vapor Pressure | 0.00000207 [mmHg] |
| LogP | -2.49 |
| LogP | log Kow = -2.49 |
| Ionization Efficiency | 1.24 |
| Ionization Efficiency | 2.7 |
L-cysteine; 52-90-4; cysteine; Cystein; (R)-2-Amino-3-mercaptopropanoic acid; Thioserine; Half-cystine; L-(+)-Cysteine; beta-Mercaptoalanine; L-Cystein; (2R)-2-amino-3-sulfanylpropanoic acid; Cysteinum; L-Cys; cisteina; Half cystine; 2-Amino-3-mercaptopropionic acid
| Regulatory & Food Contact | EU Flavoring substances FDA Substance added to food: DOUGH STRENGTHENER, FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, FLOUR TREATING Flavoring Agents FLAVOURING_AGENT: Flavouring Agent Savory DOUGH STRENGTHENER, FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, FLOUR TREATING AGENT, NUTRIENT SUPPLEMENT |
|---|---|
| GHS notification summary | 33.8% (179 / 529) |
| GHS notification summary | 33.8% (179 / 529) |
|---|---|
| Reported hazard statements | H302 (55.6%), H315 (11.9%), H319 (11.9%), H335 (11.9%) |
This chemical does not meet GHS hazard criteria for 33.8% (179 of 529) of reports.
H302 (55.6%): Harmful if swallowed [Warning Acute toxicity, oral]
L-Cystein · CAS 52-90-4 · C3H7NO2S. UNII K848JZ4886. Melting Point: 240; Melting Point: 260 °C decomposes; Melting Point: 220 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: L-半胱氨酸