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L-半胱氨酸

CAS 52-90-4C3H7NO2SMW 121.16

L-半胱氨酸(CAS 52-90-4):分子式 C3H7NO2S、分子量 121.16。

产品概览

CAS号52-90-4
分子式C3H7NO2S
分子量121.16
熔点240
LogP-2.49
应用领域Uses: CIR ingredient: Cysteine、Cysteine is a non-essential amino acid that has been used as a dough conditioner and veterinary detoxicant、[Merck Index] Used as a flavoring agent、dough strengthener、nutritional supplement、and flour treating agent for foods、[FDA] Used for biochemical and nutritional research and as a medication、[HSDB]、Reported uses (ppm):、Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association、1994) [Table#3867]、Biochemical and nutrition research、reducing agent in bread doughs (up to 90 ppm).、MEDICATION、MEDICATION (VET)、Treatment with cysteine reduced seedling injury caused by gamma-irradiation of sorghum seed. Cysteine effects were most pronounced in primary root elongation.、Use (kg) in Switzerland (2009): >10000、Use (kg、approx.) in Germany (2009): >100000、exact) in Germany (2009): 132069、Use (kg) in France (2004): 96759、Consumption (g per capita) in Switzerland (2009): 1.3、Consumption (g per capita、approx.) in Germany (2009): 1.2、exact) in Germany (2009): 1.6、Consumption (g per capita) in France (2004): 1.6、Excretion rate: 0.3、Calculated removal (%): 92.1、For the prevention of liver damage and kidney damage associated with overdoses of acetaminophen、Use Classification: Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Cosmetics -> Reducing、Antistatic、Antioxidant、Hair conditioning、Household Products: Information on 4 consumer products that contain Cysteine in the following categories is provided:、• Personal Care、Methods of Manufacturing: By addition of a thiol compound to an unsaturated amino acid derivative、by hydrolysis of proteins in the presence of carbon dioxide、by treating in HCl hydrolysis of proteins in the presence of carbon dioxide、by treating an HCl hydrolysate of hair with CuO2、followed by the decomposition of the resulting copper-cysteine complex with hydrogen sulfide、by the addition of thioacetic acid to alpha-acetamido acrylic acid、by treatment of a keratine HCl hydrolysate with zinc to reduce the cystine present to cysteine、by electrolytic reduction of cystine.、L-Cysteine used to be produced almost exclusively by hydrolysis of hair or other keratins. The amino acid isolated was l-cystine、which was reduced electrolytically to l-cysteine. L-Cysteine has also been prepared from beta-chloro-d、l-alanine and sodium sulfide with cysteine desulfhydrase、an enzyme obtained from、e.g.、Citrobacterium freundii. Today、however、the main processes for cysteine production are biological. A direct fermentation process has been developed for the manufacture of l-cystine、using a modified Escherichia coli bacterium. The technology has been extended to prepare other modified l-cysteine analogues. An enzymatic process for l-cysteine has been successfully developed using microorganisms capable to hydrolyze 2-amino-delta2-thiazoline 4-carboxylic acid (ATC) which is readily available from methyl alpha-chloroacrylate and thiourea. A mutant of Pseudomonas thiazolinophilum converts d、l-ATC to l-cysteine in 95% molar yield at product concentrations higher than 30 g、L.、Formulations、Preparations: Available commercially as L(+)-cysteine hydrochloride.、U.S. Production: Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: L-Cysteine. National Production Volume: 28、660 lb、yr.、General Manufacturing Information: L-Cysteine: ACTIVE、A non-essential amino acid in human development.、An amino acid derived from cystine、occurring naturally in the L-form ...

应用领域

登记用途:Uses: CIR ingredient: Cysteine、Cysteine is a non-essential amino acid that has been used as a dough conditioner and veterinary detoxicant、[Merck Index] Used as a flavoring agent、dough strengthener、nutritional supplement、and flour treating agent for foods、[FDA] Used for biochemical and nutritional research and as a medication、[HSDB]、Reported uses (ppm):、Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association、1994) [Table#3867]、Biochemical and nutrition research、reducing agent in bread doughs (up to 90 ppm).、MEDICATION、MEDICATION (VET)、Treatment with cysteine reduced seedling injury caused by gamma-irradiation of sorghum seed. Cysteine effects were most pronounced in primary root elongation.、Use (kg) in Switzerland (2009): >10000、Use (kg、approx.) in Germany (2009): >100000、exact) in Germany (2009): 132069、Use (kg) in France (2004): 96759、Consumption (g per capita) in Switzerland (2009): 1.3、Consumption (g per capita、approx.) in Germany (2009): 1.2、exact) in Germany (2009): 1.6、Consumption (g per capita) in France (2004): 1.6、Excretion rate: 0.3、Calculated removal (%): 92.1、For the prevention of liver damage and kidney damage associated with overdoses of acetaminophen、Use Classification: Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Cosmetics -> Reducing、Antistatic、Antioxidant、Hair conditioning、Household Products: Information on 4 consumer products that contain Cysteine in the following categories is provided:、• Personal Care、Methods of Manufacturing: By addition of a thiol compound to an unsaturated amino acid derivative、by hydrolysis of proteins in the presence of carbon dioxide、by treating in HCl hydrolysis of proteins in the presence of carbon dioxide、by treating an HCl hydrolysate of hair with CuO2、followed by the decomposition of the resulting copper-cysteine complex with hydrogen sulfide、by the addition of thioacetic acid to alpha-acetamido acrylic acid、by treatment of a keratine HCl hydrolysate with zinc to reduce the cystine present to cysteine、by electrolytic reduction of cystine.、L-Cysteine used to be produced almost exclusively by hydrolysis of hair or other keratins. The amino acid isolated was l-cystine、which was reduced electrolytically to l-cysteine. L-Cysteine has also been prepared from beta-chloro-d、l-alanine and sodium sulfide with cysteine desulfhydrase、an enzyme obtained from、e.g.、Citrobacterium freundii. Today、however、the main processes for cysteine production are biological. A direct fermentation process has been developed for the manufacture of l-cystine、using a modified Escherichia coli bacterium. The technology has been extended to prepare other modified l-cysteine analogues. An enzymatic process for l-cysteine has been successfully developed using microorganisms capable to hydrolyze 2-amino-delta2-thiazoline 4-carboxylic acid (ATC) which is readily available from methyl alpha-chloroacrylate and thiourea. A mutant of Pseudomonas thiazolinophilum converts d、l-ATC to l-cysteine in 95% molar yield at product concentrations higher than 30 g、L.、Formulations、Preparations: Available commercially as L(+)-cysteine hydrochloride.、U.S. Production: Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: L-Cysteine. National Production Volume: 28、660 lb、yr.、General Manufacturing Information: L-Cysteine: ACTIVE、A non-essential amino acid in human development.、An amino acid derived from cystine、occurring naturally in the L-form ...。

技术档案

这个产品是什么

L-半胱氨酸 是一种化工化合物,登记 CAS 号为 52-90-4,分子式 C3H7NO2S(分子量 121.16)。

识别信息

登记 CAS 号:52-90-4

其分子式 C3H7NO2S 由 3 个碳、7 个氢、1 个氮、2 个氧、1 个硫 组成。

别名/同义词:L-半胱氨酸 · L-Cystein

常见问题

L-半胱氨酸 的 CAS 号是多少?

L-半胱氨酸 的 CAS 登记号为 52-90-4。

L-半胱氨酸 的分子式与分子量是多少?

分子式 C3H7NO2S,分子量 121.16。

L-半胱氨酸 还有哪些别名?

别名/同义词:L-半胱氨酸、L-Cystein。

L-半胱氨酸 的登记用途是什么?

登记用途:Uses: CIR ingredient: Cysteine、Cysteine is a non-essential amino acid that has been used as a dough conditioner and veterinary detoxicant、[Merck Index] Used as a flavoring agent、dough strengthener、nutritional supplement、and flour treating agent for foods、[FDA] Used for biochemical and nutritional research and as a medication、[HSDB]、Reported uses (ppm):、Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association、1994) [Table#3867]、Biochemical and nutrition research、reducing agent in bread doughs (up to 90 ppm).、MEDICATION、MEDICATION (VET)、Treatment with cysteine reduced seedling injury caused by gamma-irradiation of sorghum seed. Cysteine effects were most pronounced in primary root elongation.、Use (kg) in Switzerland (2009): >10000、Use (kg、approx.) in Germany (2009): >100000、exact) in Germany (2009): 132069、Use (kg) in France (2004): 96759、Consumption (g per capita) in Switzerland (2009): 1.3、Consumption (g per capita、approx.) in Germany (2009): 1.2、exact) in Germany (2009): 1.6、Consumption (g per capita) in France (2004): 1.6、Excretion rate: 0.3、Calculated removal (%): 92.1、For the prevention of liver damage and kidney damage associated with overdoses of acetaminophen、Use Classification: Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Cosmetics -> Reducing、Antistatic、Antioxidant、Hair conditioning、Household Products: Information on 4 consumer products that contain Cysteine in the following categories is provided:、• Personal Care、Methods of Manufacturing: By addition of a thiol compound to an unsaturated amino acid derivative、by hydrolysis of proteins in the presence of carbon dioxide、by treating in HCl hydrolysis of proteins in the presence of carbon dioxide、by treating an HCl hydrolysate of hair with CuO2、followed by the decomposition of the resulting copper-cysteine complex with hydrogen sulfide、by the addition of thioacetic acid to alpha-acetamido acrylic acid、by treatment of a keratine HCl hydrolysate with zinc to reduce the cystine present to cysteine、by electrolytic reduction of cystine.、L-Cysteine used to be produced almost exclusively by hydrolysis of hair or other keratins. The amino acid isolated was l-cystine、which was reduced electrolytically to l-cysteine. L-Cysteine has also been prepared from beta-chloro-d、l-alanine and sodium sulfide with cysteine desulfhydrase、an enzyme obtained from、e.g.、Citrobacterium freundii. Today、however、the main processes for cysteine production are biological. A direct fermentation process has been developed for the manufacture of l-cystine、using a modified Escherichia coli bacterium. The technology has been extended to prepare other modified l-cysteine analogues. An enzymatic process for l-cysteine has been successfully developed using microorganisms capable to hydrolyze 2-amino-delta2-thiazoline 4-carboxylic acid (ATC) which is readily available from methyl alpha-chloroacrylate and thiourea. A mutant of Pseudomonas thiazolinophilum converts d、l-ATC to l-cysteine in 95% molar yield at product concentrations higher than 30 g、L.、Formulations、Preparations: Available commercially as L(+)-cysteine hydrochloride.、U.S. Production: Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: L-Cysteine. National Production Volume: 28、660 lb、yr.、General Manufacturing Information: L-Cysteine: ACTIVE、A non-essential amino acid in human development.、An amino acid derived from cystine、occurring naturally in the L-form ...。

PubChem 公开数据

L-半胱氨酸(CAS 52-90-4)的独立参考数据,整理自公开化学数据库。

各数据库的登记标识

CAS Registry Number52-90-4
PubChem CID5862
Molecular formulaC3H7NO2S
IUPAC name(2R)-2-amino-3-sulfanylpropanoic acid
UNII (FDA)K848JZ4886
FEMA number3263
JECFA number1419

计算分子描述符

Molecular Weight121.16
XLogP3-2.5
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass121.01974964
Monoisotopic Mass121.01974964
Topological Polar Surface Area64.3
Heavy Atom Count7

在册的理化数值

Melting Point240
Melting Point260 °C decomposes
Melting Point220 °C
Solubility277000
Solubility277 mg/mL at 25 °C
Vapor Pressure0.00000207 [mmHg]
LogP-2.49
LogPlog Kow = -2.49
Ionization Efficiency1.24
Ionization Efficiency2.7

在册的记载用途

    Cysteine is a non-essential amino acid that has been used as a dough conditioner and veterinary detoxicant; [Merck Index] Used as a flavoring agent, dough strengthener, nutritional supplement, and flour treating agent for foods; [FDA] Used for biochemical and nutritional research and as a medication; [HSDB]Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association, 1994) [Table#3867]

    同义词与商品名

    L-cysteine; 52-90-4; cysteine; Cystein; (R)-2-Amino-3-mercaptopropanoic acid; Thioserine; Half-cystine; L-(+)-Cysteine; beta-Mercaptoalanine; L-Cystein; (2R)-2-amino-3-sulfanylpropanoic acid; Cysteinum; L-Cys; cisteina; Half cystine; 2-Amino-3-mercaptopropionic acid

    已收录的法规名录

    Regulatory & Food ContactEU Flavoring substances
    FDA Substance added to food: DOUGH STRENGTHENER, FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, FLOUR TREATING
    Flavoring Agents
    FLAVOURING_AGENT: Flavouring Agent
    Savory
    DOUGH STRENGTHENER, FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, FLOUR TREATING AGENT, NUTRIENT SUPPLEMENT
    GHS notification summary33.8% (179 / 529)

    GHS 危害分类

    GHS notification summary33.8% (179 / 529)
    Reported hazard statementsH302 (55.6%), H315 (11.9%), H319 (11.9%), H335 (11.9%)

    This chemical does not meet GHS hazard criteria for 33.8% (179 of 529) of reports.

    H302 (55.6%): Harmful if swallowed [Warning Acute toxicity, oral]

    公开数据库对它的描述

    L-Cystein · CAS 52-90-4 · C3H7NO2S. UNII K848JZ4886. Melting Point: 240; Melting Point: 260 °C decomposes; Melting Point: 220 °C.

    物理形态与操作说明

    数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。

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