异山梨醇（CAS 652-67-5）：分子式 C6H10O4、分子量 146.14；类别 食品添加剂。
| CAS号 | 652-67-5 |
|---|---|
| 分子式 | C6H10O4 |
| 分子量 | 146.14 |
| 熔点 | 60-63 |
| 沸点 | 175 |
| LogP | -1.4 |
| 应用领域 | Uses: MEDICATION、MEDICATION (VET)、Industry Uses: Lubricating agent、Not Known or Reasonably Ascertainable、Consumer Uses: Not Known or Reasonably Ascertainable、Methods of Manufacturing: PREPARED BY ACID DEHYDRATION OF D-GLUCITOL: HAWORTH、WIGGINS、BRITISH PATENT 600、870 (1948). PURIFICATION: HARTMANN、US PATENT 3、160、641 (1964 TO ATLAS CHEM INDUSTRIES).、Formulations、Preparations: ISMOTIC (ALCON)、ORAL AS 45% SOLUTION.、U.S. Production: 2023: 80、993 lb、2022: 118、277 lb、2021: 444、894 lb、2020: 190、753 lb、General Manufacturing Information: Plastics Material and Resin Manufacturing、Utilities、D-Glucitol、1、4:3、6-dianhydro-: ACTIVE、A POLYOL WITH HYDROXYL GROUP ATTACHED TO EACH OF TWO CIS-ORIENTED SATURATED FURAN RINGS. |
| 类别 | 其他食品添加剂 |
登记用途：Uses: MEDICATION、MEDICATION (VET)、Industry Uses: Lubricating agent、Not Known or Reasonably Ascertainable、Consumer Uses: Not Known or Reasonably Ascertainable、Methods of Manufacturing: PREPARED BY ACID DEHYDRATION OF D-GLUCITOL: HAWORTH、WIGGINS、BRITISH PATENT 600、870 (1948). PURIFICATION: HARTMANN、US PATENT 3、160、641 (1964 TO ATLAS CHEM INDUSTRIES).、Formulations、Preparations: ISMOTIC (ALCON)、ORAL AS 45% SOLUTION.、U.S. Production: 2023: 80、993 lb、2022: 118、277 lb、2021: 444、894 lb、2020: 190、753 lb、General Manufacturing Information: Plastics Material and Resin Manufacturing、Utilities、D-Glucitol、1、4:3、6-dianhydro-: ACTIVE、A POLYOL WITH HYDROXYL GROUP ATTACHED TO EACH OF TWO CIS-ORIENTED SATURATED FURAN RINGS.。
异山梨醇 是一种食品级化合物，登记 CAS 号为 652-67-5，分子式 C6H10O4（分子量 146.14），归属于食品添加剂大类化工原料。
登记 CAS 号：652-67-5
其分子式 C6H10O4 由 6 个碳、10 个氢、4 个氧 组成。
别名/同义词：异山梨醇 · Isosorbide
所属分类：食品添加剂
异山梨醇 的 CAS 登记号为 652-67-5。
分子式 C6H10O4，分子量 146.14。
别名/同义词：异山梨醇、Isosorbide。
登记用途：Uses: MEDICATION、MEDICATION (VET)、Industry Uses: Lubricating agent、Not Known or Reasonably Ascertainable、Consumer Uses: Not Known or Reasonably Ascertainable、Methods of Manufacturing: PREPARED BY ACID DEHYDRATION OF D-GLUCITOL: HAWORTH、WIGGINS、BRITISH PATENT 600、870 (1948). PURIFICATION: HARTMANN、US PATENT 3、160、641 (1964 TO ATLAS CHEM INDUSTRIES).、Formulations、Preparations: ISMOTIC (ALCON)、ORAL AS 45% SOLUTION.、U.S. Production: 2023: 80、993 lb、2022: 118、277 lb、2021: 444、894 lb、2020: 190、753 lb、General Manufacturing Information: Plastics Material and Resin Manufacturing、Utilities、D-Glucitol、1、4:3、6-dianhydro-: ACTIVE、A POLYOL WITH HYDROXYL GROUP ATTACHED TO EACH OF TWO CIS-ORIENTED SATURATED FURAN RINGS.。
所属分类：其他食品添加剂。
异山梨醇（CAS 652-67-5）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 652-67-5 |
|---|---|
| PubChem CID | 12597 |
| Molecular formula | C6H10O4 |
| Molecular weight | 146.06 g/mol |
| IUPAC name | (3S,3aR,6R,6aR)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol |
| InChIKey | KLDXJTOLSGUMSJ-JGWLITMVSA-N |
| UNII (FDA) | WXR179L51S |
| ChEBI ID | CHEBI:6060 |
| Molecular Weight | 146.14 |
|---|---|
| XLogP3 | -1.4 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 0 |
| Exact Mass | 146.05790880 |
| Monoisotopic Mass | 146.05790880 |
| Topological Polar Surface Area | 58.9 |
| Heavy Atom Count | 10 |
| Boiling Point | 175 |
|---|---|
| Melting Point | 60-63 |
| Melting Point | 61-64 °C |
| Solubility | 29 |
isosorbide; 652-67-5; Isobide; Devicoran; 1,4:3,6-Dianhydro-D-glucitol; Hydronol; Ismotic; (3R,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diol; (+)-D-Isosorbide; D-Glucitol, 1,4:3,6-dianhydro-; 1,4:3,6-Dianhydro-D-sorbitol; 1,4:3,6-Dianhydrosorbitol; DTXSID5046196; NSC-40725; Glucitol, 1,4:3,6-dianhydro-, D-; WXR179L51S
| Regulatory & Food Contact | FDA Cumulative Estimated Daily Intake (CEDI): FCS |
|---|---|
| GHS notification summary | 99.3% (145 / 146) |
| GHS notification summary | 99.3% (145 / 146) |
|---|
This chemical does not meet GHS hazard criteria for 99.3% (145 of 146) of all reports.
Reported as not meeting GHS hazard criteria by 145 of 146 companies (only 0.7% companies provided GHS information). For more detailed information, please visit ECHA C&L website.
Isosorbide is identified by CAS 652-67-5, molecular formula C6H10O4 and molecular weight 146.06 g/mol. UNII WXR179L51S; ChEBI 6060; InChIKey KLDXJTOLSGUMSJ-JGWLITMVSA-N. Boiling Point: 175; Melting Point: 60-63; Melting Point: 61-64 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Isosorbide