Flurandrenolide (CAS 1524-88-5) — formula C24H33FO6, molecular weight 436.5; category organic chemicals.
| CAS Number | 1524-88-5 |
|---|---|
| Molecular Formula | C24H33FO6 |
| Molecular Weight | 436.5 |
| Melting Point | 251 |
| LogP | 0.6 |
| Applications | Uses: For relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, particularly dry, scaling localized lesions., THERAP CAT: Glucocorticoid, antipsoriatic, MEDICATION, Use Classification: Pharmaceuticals, Methods of Manufacturing: Prepn: Ringold et al, German patent 1, 131, 213 corresponds to US patent 3, 126, 375 (1962, 1964 both to Syntex)., FLURANDRENOLONE (6ALPHA-FLUORO-16ALPHA-HYDROXY-CORTISOL) IS CONDENSED WITH ACETONE BY TREATING ITS SOLN IN ACETONE WITH 70% PERCHLORIC ACID., Formulations, Preparations: Topical: Cream: 0.05% Cordran SP (with propylene glycol), (Watson), Dressing 4 ug, sq cm Cordran Tape, (Watson). Lotion: 0.05% Cordran (with benzyl alcohol), (Watson). Ointment: 0.05% Cordran, (Watson)., General Manufacturing Information: NEOMYCIN IS OFTEN INCL IN TOPICAL PREPN OF FLURANDRENOLIDE TO SUPPRESS INFECTIONS SECONDARY TO INFLAMMATORY PROCESS OR TO USE OF GLUCOCORTICOID. |
| Category | Organic Chemicals |
Documented applications: Uses: For relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, particularly dry, scaling localized lesions., THERAP CAT: Glucocorticoid, antipsoriatic, MEDICATION, Use Classification: Pharmaceuticals, Methods of Manufacturing: Prepn: Ringold et al, German patent 1, 131, 213 corresponds to US patent 3, 126, 375 (1962, 1964 both to Syntex)., FLURANDRENOLONE (6ALPHA-FLUORO-16ALPHA-HYDROXY-CORTISOL) IS CONDENSED WITH ACETONE BY TREATING ITS SOLN IN ACETONE WITH 70% PERCHLORIC ACID., Formulations, Preparations: Topical: Cream: 0.05% Cordran SP (with propylene glycol), (Watson), Dressing 4 ug, sq cm Cordran Tape, (Watson). Lotion: 0.05% Cordran (with benzyl alcohol), (Watson). Ointment: 0.05% Cordran, (Watson)., General Manufacturing Information: NEOMYCIN IS OFTEN INCL IN TOPICAL PREPN OF FLURANDRENOLIDE TO SUPPRESS INFECTIONS SECONDARY TO INFLAMMATORY PROCESS OR TO USE OF GLUCOCORTICOID..
Flurandrenolide is a carbon-based organic compound with CAS registry number 1524-88-5 and molecular formula C24H33FO6 (molecular weight 436.5), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 1524-88-5
Its molecular formula C24H33FO6 comprises 24 C, 33 H, 1 F, 6 O atoms.
Also known as: Flurandrenolide · 氟肾上腺素内酯
Category: organic chemicals
The CAS registry number of Flurandrenolide is 1524-88-5.
Molecular formula C24H33FO6, molecular weight 436.5.
It is also registered under: Flurandrenolide, 氟肾上腺素内酯.
Recorded applications: Uses: For relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, particularly dry, scaling localized lesions., THERAP CAT: Glucocorticoid, antipsoriatic, MEDICATION, Use Classification: Pharmaceuticals, Methods of Manufacturing: Prepn: Ringold et al, German patent 1, 131, 213 corresponds to US patent 3, 126, 375 (1962, 1964 both to Syntex)., FLURANDRENOLONE (6ALPHA-FLUORO-16ALPHA-HYDROXY-CORTISOL) IS CONDENSED WITH ACETONE BY TREATING ITS SOLN IN ACETONE WITH 70% PERCHLORIC ACID., Formulations, Preparations: Topical: Cream: 0.05% Cordran SP (with propylene glycol), (Watson), Dressing 4 ug, sq cm Cordran Tape, (Watson). Lotion: 0.05% Cordran (with benzyl alcohol), (Watson). Ointment: 0.05% Cordran, (Watson)., General Manufacturing Information: NEOMYCIN IS OFTEN INCL IN TOPICAL PREPN OF FLURANDRENOLIDE TO SUPPRESS INFECTIONS SECONDARY TO INFLAMMATORY PROCESS OR TO USE OF GLUCOCORTICOID..
Category: Organic Chemicals.
Independent reference data for Flurandrenolide (CAS 1524-88-5), compiled from public chemistry databases.
| CAS Registry Number | 1524-88-5 |
|---|---|
| PubChem CID | 15209 |
| Molecular formula | C24H33FO6 |
| IUPAC name | (1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one |
| UNII (FDA) | 8EUL29XUQT |
| Molecular Weight | 436.5 |
|---|---|
| XLogP3 | 1.4 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 2 |
| Exact Mass | 436.22611693 |
| Monoisotopic Mass | 436.22611693 |
| Topological Polar Surface Area | 93.1 |
| Heavy Atom Count | 31 |
| Melting Point | 251 |
|---|---|
| Melting Point | 247-255 °C |
| Melting Point | 251 °C |
| Solubility | 5.78e-02 g/L |
| LogP | 0.6 |
flurandrenolide; Fludroxycortide; 1524-88-5; Flurandrenolone; Cordran; Haelan; Fluorandrenolone; Drenison; Drocort; Sermaka; Flurandrenolone acetonide; Fluorandrenolone acetonide; Haldrone-F; Alondra-F; Fludroxicortida; Fludroxycortidum
| Reported hazard statements | H319 (97.6%) |
|---|
H319 (97.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)
Flurandrenolide · CAS 1524-88-5 · C24H33FO6. UNII 8EUL29XUQT. Melting Point: 251; Melting Point: 247-255 °C; Melting Point: 251 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 氟肾上腺素内酯