氟肾上腺素内酯（CAS 1524-88-5）：分子式 C24H33FO6、分子量 436.5。
| CAS号 | 1524-88-5 |
|---|---|
| 分子式 | C24H33FO6 |
| 分子量 | 436.5 |
| 熔点 | 251 |
| LogP | 0.6 |
| 应用领域 | Uses: For relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses、particularly dry、scaling localized lesions.、THERAP CAT: Glucocorticoid、antipsoriatic、MEDICATION、Use Classification: Pharmaceuticals、Methods of Manufacturing: Prepn: Ringold et al、German patent 1、131、213 corresponds to US patent 3、126、375 (1962、1964 both to Syntex).、FLURANDRENOLONE (6ALPHA-FLUORO-16ALPHA-HYDROXY-CORTISOL) IS CONDENSED WITH ACETONE BY TREATING ITS SOLN IN ACETONE WITH 70% PERCHLORIC ACID.、Formulations、Preparations: Topical: Cream: 0.05% Cordran SP (with propylene glycol)、(Watson)、Dressing 4 ug、sq cm Cordran Tape、(Watson). Lotion: 0.05% Cordran (with benzyl alcohol)、(Watson). Ointment: 0.05% Cordran、(Watson).、General Manufacturing Information: NEOMYCIN IS OFTEN INCL IN TOPICAL PREPN OF FLURANDRENOLIDE TO SUPPRESS INFECTIONS SECONDARY TO INFLAMMATORY PROCESS OR TO USE OF GLUCOCORTICOID. |
登记用途：Uses: For relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses、particularly dry、scaling localized lesions.、THERAP CAT: Glucocorticoid、antipsoriatic、MEDICATION、Use Classification: Pharmaceuticals、Methods of Manufacturing: Prepn: Ringold et al、German patent 1、131、213 corresponds to US patent 3、126、375 (1962、1964 both to Syntex).、FLURANDRENOLONE (6ALPHA-FLUORO-16ALPHA-HYDROXY-CORTISOL) IS CONDENSED WITH ACETONE BY TREATING ITS SOLN IN ACETONE WITH 70% PERCHLORIC ACID.、Formulations、Preparations: Topical: Cream: 0.05% Cordran SP (with propylene glycol)、(Watson)、Dressing 4 ug、sq cm Cordran Tape、(Watson). Lotion: 0.05% Cordran (with benzyl alcohol)、(Watson). Ointment: 0.05% Cordran、(Watson).、General Manufacturing Information: NEOMYCIN IS OFTEN INCL IN TOPICAL PREPN OF FLURANDRENOLIDE TO SUPPRESS INFECTIONS SECONDARY TO INFLAMMATORY PROCESS OR TO USE OF GLUCOCORTICOID.。
氟肾上腺素内酯 是一种化工化合物，登记 CAS 号为 1524-88-5，分子式 C24H33FO6（分子量 436.5）。
登记 CAS 号：1524-88-5
其分子式 C24H33FO6 由 24 个碳、33 个氢、1 个氟、6 个氧 组成。
别名/同义词：氟肾上腺素内酯 · Flurandrenolide
氟肾上腺素内酯 的 CAS 登记号为 1524-88-5。
分子式 C24H33FO6，分子量 436.5。
别名/同义词：氟肾上腺素内酯、Flurandrenolide。
登记用途：Uses: For relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses、particularly dry、scaling localized lesions.、THERAP CAT: Glucocorticoid、antipsoriatic、MEDICATION、Use Classification: Pharmaceuticals、Methods of Manufacturing: Prepn: Ringold et al、German patent 1、131、213 corresponds to US patent 3、126、375 (1962、1964 both to Syntex).、FLURANDRENOLONE (6ALPHA-FLUORO-16ALPHA-HYDROXY-CORTISOL) IS CONDENSED WITH ACETONE BY TREATING ITS SOLN IN ACETONE WITH 70% PERCHLORIC ACID.、Formulations、Preparations: Topical: Cream: 0.05% Cordran SP (with propylene glycol)、(Watson)、Dressing 4 ug、sq cm Cordran Tape、(Watson). Lotion: 0.05% Cordran (with benzyl alcohol)、(Watson). Ointment: 0.05% Cordran、(Watson).、General Manufacturing Information: NEOMYCIN IS OFTEN INCL IN TOPICAL PREPN OF FLURANDRENOLIDE TO SUPPRESS INFECTIONS SECONDARY TO INFLAMMATORY PROCESS OR TO USE OF GLUCOCORTICOID.。
氟肾上腺素内酯（CAS 1524-88-5）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 1524-88-5 |
|---|---|
| PubChem CID | 15209 |
| Molecular formula | C24H33FO6 |
| IUPAC name | (1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one |
| UNII (FDA) | 8EUL29XUQT |
| Molecular Weight | 436.5 |
|---|---|
| XLogP3 | 1.4 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 2 |
| Exact Mass | 436.22611693 |
| Monoisotopic Mass | 436.22611693 |
| Topological Polar Surface Area | 93.1 |
| Heavy Atom Count | 31 |
| Melting Point | 251 |
|---|---|
| Melting Point | 247-255 °C |
| Melting Point | 251 °C |
| Solubility | 5.78e-02 g/L |
| LogP | 0.6 |
flurandrenolide; Fludroxycortide; 1524-88-5; Flurandrenolone; Cordran; Haelan; Fluorandrenolone; Drenison; Drocort; Sermaka; Flurandrenolone acetonide; Fluorandrenolone acetonide; Haldrone-F; Alondra-F; Fludroxicortida; Fludroxycortidum
| Reported hazard statements | H319 (97.6%) |
|---|
H319 (97.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)
Flurandrenolide · CAS 1524-88-5 · C24H33FO6. UNII 8EUL29XUQT. Melting Point: 251; Melting Point: 247-255 °C; Melting Point: 251 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Flurandrenolide