Donepezil

CAS 142057-79-2C24H29NO3MW 379.5

Donepezil (CAS 142057-79-2) — formula C24H29NO3, molecular weight 379.5.

Product Overview

CAS Number	142057-79-2
Molecular Formula	C24H29NO3
Molecular Weight	379.5
Melting Point	223-227
Boiling Point	527.9
LogP	4.7

Technical Profile

What this product is

Donepezil is a chemical compound with CAS registry number 142057-79-2 and molecular formula C24H29NO3 (molecular weight 379.5).

Identification

CAS number: 142057-79-2

Its molecular formula C24H29NO3 comprises 24 C, 29 H, 1 N, 3 O atoms.

Also known as: Donepezil · 多奈哌齐

Frequently Asked Questions

What is the CAS number of Donepezil?

The CAS registry number of Donepezil is 142057-79-2.

What is the molecular formula and molecular weight of Donepezil?

Molecular formula C24H29NO3, molecular weight 379.5.

What other names is Donepezil known by?

It is also registered under: Donepezil, 多奈哌齐.

PubChem Public Data

Independent reference data for Donepezil (CAS 142057-79-2), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number	142057-79-2
PubChem CID	3152
Molecular formula	C24H29NO3
IUPAC name	2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
UNII (FDA)	8SSC91326P

Computed descriptors

Molecular Weight	379.5
XLogP3	4.3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	6
Exact Mass	379.21474379
Monoisotopic Mass	379.21474379
Topological Polar Surface Area	38.8
Heavy Atom Count	28

Physicochemical values on record

Boiling Point	527.9
Melting Point	223-227
Solubility	31mg/mL
LogP	4.7
LogP	4.11
Dissociation Constants	9.08
Dissociation Constants	8.9

Documented uses on record

Synonyms and trade names

donepezil; 120014-06-4; donepezilo; Donaz; donepezilum; Domepezil; 8SSC91326P; D-797; 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-; DTXSID8048317; CHEBI:53289; 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-((1-(phenylmethyl)-4-piperidinyl)methyl)-; donezpil hydrochloride; 5,6-dimethoxy-2-((1-(phenylmethyl)piperidin-4-yl)methyl)-2,3-dihydroinden-1-one; 5,6-dimethoxy-2-[[1-(phenylmethyl)piperidin-4-yl]methyl]-2,3-dihydroinden-1-one; donepezil hydrochlorid

GHS hazard classification

Reported hazard statements	H300 (88.9%), H302 (11.1%), H315 (11.1%), H319 (22.2%), H335 (11.1%), H413 (11.1%)

H300 (88.9%): Fatal if swallowed [Danger Acute toxicity, oral]

H302 (11.1%): Harmful if swallowed [Warning Acute toxicity, oral]

What the public record says

Donepezil · CAS 142057-79-2 · C24H29NO3. UNII 8SSC91326P. Boiling Point: 527.9; Melting Point: 223-227; Solubility: 31mg/mL.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.