多奈哌齐

CAS 142057-79-2C24H29NO3MW 379.5

多奈哌齐（CAS 142057-79-2）：分子式 C24H29NO3、分子量 379.5。

产品概览

CAS号	142057-79-2
分子式	C24H29NO3
分子量	379.5
熔点	223-227
沸点	527.9
LogP	4.7
应用领域	Uses: ... in the treatment of Alzheimer's Disease、... has also been studied in patients with Mild Cognitive Impairment、schizophrenia、attention deficit disorder、post-coronary bypass cognitive impairment、cognitive impairment associated with multiple sclerosis、and Down syndrome.、THERAP CAT: Nootropic、SRP: Memory or cognition enhancer、Use (kg、approx.) in Germany (2009): >100、Use (kg) in USA (2002): 607、Consumption (g per capita、approx.) in Germany (2009): 0.00122、Consumption (g per capita) in the USA (2002): 0.00215、Calculated removal (%): 85.9、For the palliative treatment of mild to moderate dementia of the Alzheimer's type.、Use Classification: Pharmaceuticals、Methods of Manufacturing: Preparation: H. Sugimoto et al.、EP 296560、eidem、US 4895841 (1988、1990 both to Eisai).、Formulations、Preparations: Formulations: (AHFS、2009)、Table: Donepezil preparations: (AHFS、2009) [Table#7409]

应用领域

登记用途：Uses: ... in the treatment of Alzheimer's Disease、... has also been studied in patients with Mild Cognitive Impairment、schizophrenia、attention deficit disorder、post-coronary bypass cognitive impairment、cognitive impairment associated with multiple sclerosis、and Down syndrome.、THERAP CAT: Nootropic、SRP: Memory or cognition enhancer、Use (kg、approx.) in Germany (2009): >100、Use (kg) in USA (2002): 607、Consumption (g per capita、approx.) in Germany (2009): 0.00122、Consumption (g per capita) in the USA (2002): 0.00215、Calculated removal (%): 85.9、For the palliative treatment of mild to moderate dementia of the Alzheimer's type.、Use Classification: Pharmaceuticals、Methods of Manufacturing: Preparation: H. Sugimoto et al.、EP 296560、eidem、US 4895841 (1988、1990 both to Eisai).、Formulations、Preparations: Formulations: (AHFS、2009)、Table: Donepezil preparations: (AHFS、2009) [Table#7409]。

技术档案

这个产品是什么

多奈哌齐是一种化工化合物，登记 CAS 号为 142057-79-2，分子式 C24H29NO3（分子量 379.5）。

识别信息

登记 CAS 号：142057-79-2

其分子式 C24H29NO3 由 24 个碳、29 个氢、1 个氮、3 个氧组成。

别名/同义词：多奈哌齐 · Donepezil

常见问题

多奈哌齐的 CAS 号是多少？

多奈哌齐的 CAS 登记号为 142057-79-2。

多奈哌齐的分子式与分子量是多少？

分子式 C24H29NO3，分子量 379.5。

多奈哌齐还有哪些别名？

别名/同义词：多奈哌齐、Donepezil。

多奈哌齐的登记用途是什么？

PubChem 公开数据

多奈哌齐（CAS 142057-79-2）的独立参考数据，整理自公开化学数据库。

各数据库的登记标识

CAS Registry Number	142057-79-2
PubChem CID	3152
Molecular formula	C24H29NO3
IUPAC name	2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
UNII (FDA)	8SSC91326P

计算分子描述符

Molecular Weight	379.5
XLogP3	4.3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	6
Exact Mass	379.21474379
Monoisotopic Mass	379.21474379
Topological Polar Surface Area	38.8
Heavy Atom Count	28

在册的理化数值

Boiling Point	527.9
Melting Point	223-227
Solubility	31mg/mL
LogP	4.7
LogP	4.11
Dissociation Constants	9.08
Dissociation Constants	8.9

在册的记载用途

同义词与商品名

donepezil; 120014-06-4; donepezilo; Donaz; donepezilum; Domepezil; 8SSC91326P; D-797; 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-; DTXSID8048317; CHEBI:53289; 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-((1-(phenylmethyl)-4-piperidinyl)methyl)-; donezpil hydrochloride; 5,6-dimethoxy-2-((1-(phenylmethyl)piperidin-4-yl)methyl)-2,3-dihydroinden-1-one; 5,6-dimethoxy-2-[[1-(phenylmethyl)piperidin-4-yl]methyl]-2,3-dihydroinden-1-one; donepezil hydrochlorid

GHS 危害分类

Reported hazard statements	H300 (88.9%), H302 (11.1%), H315 (11.1%), H319 (22.2%), H335 (11.1%), H413 (11.1%)

H300 (88.9%): Fatal if swallowed [Danger Acute toxicity, oral]

H302 (11.1%): Harmful if swallowed [Warning Acute toxicity, oral]

公开数据库对它的描述

Donepezil · CAS 142057-79-2 · C24H29NO3. UNII 8SSC91326P. Boiling Point: 527.9; Melting Point: 223-227; Solubility: 31mg/mL.

物理形态与操作说明

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。