二环己基碳二亚胺（CAS 538-75-0）：分子式 C13H22N2、分子量 206.33；类别 医药中间体。
| CAS号 | 538-75-0 |
|---|---|
| 分子式 | C13H22N2 |
| 分子量 | 206.33 |
| 熔点 | 93 to 95 °F (NTP, 1992) |
| 沸点 | 252 to 255 °F at 6 mmHg (NTP, 1992) |
| LogP | 4.7 |
| 应用领域 | Uses: Used in chemical synthesis、[Hawley] Used as a coupling reagent in peptide chemistry、[Kanerva、p. 1781]、Dicyclohexylcarbodiimide is used in industry as a stabilizing agent、coupling agent、and condensing agent. It has widespread use during protein synthesis in the recombinant DNA industry and in the synthesis of polypeptides in the chemical and pharmaceutical industries.[DHHS、NTP、Toxicology Studies of Dicyclohexylcarbodiimide (CAS No. 538-75-0) in F344、N Rats、B6C3F1 Mice、and Genetically Modified (FVB Tg.AC Hemizygous) Mice and Carcinogenicity Study of Dicyclohexylcarbodiimide in Genetically Modified、Widely used reagent in the chemical and pharmaceutical industries、increasing use in field of bioenergetics、stabilizing agent in elastomers、natural rubber、and many types of polyolefins、polyesters、resins、fibers、cellulose esters、etc、Industry Uses: Polymerization promoter、Methods of Manufacturing: Preparation: ...Schmidt、Schnegg、US 2656383 (1953 to Bayer)、U.S. Production: 2022: 14、109 lb、2021: 109、348 lb、2020: 13、669 lb、Production volumes for non-confidential chemicals reported under the Inventory Update Rule.[Table#8038]、General Manufacturing Information: Petrochemical Manufacturing、Cyclohexanamine、N、N'-methanetetraylbis-: ACTIVE |
| 类别 | 医药中间体 |
登记用途：Uses: Used in chemical synthesis、[Hawley] Used as a coupling reagent in peptide chemistry、[Kanerva、p. 1781]、Dicyclohexylcarbodiimide is used in industry as a stabilizing agent、coupling agent、and condensing agent. It has widespread use during protein synthesis in the recombinant DNA industry and in the synthesis of polypeptides in the chemical and pharmaceutical industries.[DHHS、NTP、Toxicology Studies of Dicyclohexylcarbodiimide (CAS No. 538-75-0) in F344、N Rats、B6C3F1 Mice、and Genetically Modified (FVB Tg.AC Hemizygous) Mice and Carcinogenicity Study of Dicyclohexylcarbodiimide in Genetically Modified、Widely used reagent in the chemical and pharmaceutical industries、increasing use in field of bioenergetics、stabilizing agent in elastomers、natural rubber、and many types of polyolefins、polyesters、resins、fibers、cellulose esters、etc、Industry Uses: Polymerization promoter、Methods of Manufacturing: Preparation: ...Schmidt、Schnegg、US 2656383 (1953 to Bayer)、U.S. Production: 2022: 14、109 lb、2021: 109、348 lb、2020: 13、669 lb、Production volumes for non-confidential chemicals reported under the Inventory Update Rule.[Table#8038]、General Manufacturing Information: Petrochemical Manufacturing、Cyclohexanamine、N、N'-methanetetraylbis-: ACTIVE。
二环己基碳二亚胺 是一种化工化合物，登记 CAS 号为 538-75-0，分子式 C13H22N2（分子量 206.33），归属于医药中间体大类化工原料。
登记 CAS 号：538-75-0
其分子式 C13H22N2 由 13 个碳、22 个氢、2 个氮 组成。
别名/同义词：二环己基碳二亚胺 · Dicyclohexylcarbodiimide
所属分类：医药中间体
二环己基碳二亚胺 的 CAS 登记号为 538-75-0。
分子式 C13H22N2，分子量 206.33。
别名/同义词：二环己基碳二亚胺、Dicyclohexylcarbodiimide。
登记用途：Uses: Used in chemical synthesis、[Hawley] Used as a coupling reagent in peptide chemistry、[Kanerva、p. 1781]、Dicyclohexylcarbodiimide is used in industry as a stabilizing agent、coupling agent、and condensing agent. It has widespread use during protein synthesis in the recombinant DNA industry and in the synthesis of polypeptides in the chemical and pharmaceutical industries.[DHHS、NTP、Toxicology Studies of Dicyclohexylcarbodiimide (CAS No. 538-75-0) in F344、N Rats、B6C3F1 Mice、and Genetically Modified (FVB Tg.AC Hemizygous) Mice and Carcinogenicity Study of Dicyclohexylcarbodiimide in Genetically Modified、Widely used reagent in the chemical and pharmaceutical industries、increasing use in field of bioenergetics、stabilizing agent in elastomers、natural rubber、and many types of polyolefins、polyesters、resins、fibers、cellulose esters、etc、Industry Uses: Polymerization promoter、Methods of Manufacturing: Preparation: ...Schmidt、Schnegg、US 2656383 (1953 to Bayer)、U.S. Production: 2022: 14、109 lb、2021: 109、348 lb、2020: 13、669 lb、Production volumes for non-confidential chemicals reported under the Inventory Update Rule.[Table#8038]、General Manufacturing Information: Petrochemical Manufacturing、Cyclohexanamine、N、N'-methanetetraylbis-: ACTIVE。
所属分类：医药中间体。
二环己基碳二亚胺（CAS 538-75-0）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 538-75-0 |
|---|---|
| PubChem CID | 10868 |
| Molecular formula | C13H22N2 |
| IUPAC name | N,N'-dicyclohexylmethanediimine |
| UNII (FDA) | 0T1427205E |
| Molecular Weight | 206.33 |
|---|---|
| XLogP3 | 4.7 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 2 |
| Exact Mass | 206.178298710 |
| Monoisotopic Mass | 206.178298710 |
| Topological Polar Surface Area | 24.7 |
| Heavy Atom Count | 15 |
| Boiling Point | 252 to 255 °F at 6 mmHg (NTP, 1992) |
|---|---|
| Boiling Point | BP: 154-156 °C at 11 mm Hg |
| Melting Point | 93 to 95 °F (NTP, 1992) |
| Melting Point | 34.5 °C |
| Other Experimental Properties | Set point = 29-30 °C |
DICYCLOHEXYLCARBODIIMIDE; 538-75-0; N,N'-Dicyclohexylcarbodiimide; 1,3-Dicyclohexylcarbodiimide; DCCD; DCCI; Carbodicyclohexylimide; Bis(cyclohexyl)carbodiimide; Carbodiimide, dicyclohexyl-; Cyclohexanamine, N,N'-methanetetraylbis-; dicyclohexylmethanediimine; N,N'-Methanetetraylbiscyclohexaamine; DTXSID1023817; Dicyclohexyl-Carbodiimide; CHEBI:53090; NSC-30022
| Reported hazard statements | H302, H311, H317, H318, H315 (20.6%), H400 (14.5%), H410 (14.9%), H413 (20.6%) |
|---|
H302: Harmful if swallowed [Warning Acute toxicity, oral]
H311: Toxic in contact with skin [Danger Acute toxicity, dermal]
Dicyclohexylcarbodiimide · CAS 538-75-0 · C13H22N2. UNII 0T1427205E. Boiling Point: 252 to 255 °F at 6 mmHg (NTP, 1992); Boiling Point: BP: 154-156 °C at 11 mm Hg; Melting Point: 93 to 95 °F (NTP, 1992).
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Dicyclohexylcarbodiimide