1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one (CAS 1506-02-1) — formula C18H26O, molecular weight 258.4; category organic chemicals.
| CAS Number | 1506-02-1 |
|---|---|
| Molecular Formula | C18H26O |
| Molecular Weight | 258.4 |
| Melting Point | 54.5 °C |
| LogP | log Kow = 5.70 |
| Applications | Uses: Used as fragrance for cosmetics, detergents, fabric softeners, household cleaning products, and air fresheners, [HSDB], ... used in soap and cosmetics, Used as a fragrance in cosmetics, household cleaning products and air fresheners, Use Classification: Fragrance Ingredients, Fragrance Ingredients, Cosmetics -> Masking, Industry Uses: Fragrance, Fragrance, Consumer Uses: Fragrance, Household Products: Information on 13 consumer products that contain Acetyl Hexamethyl Tetralin in the following categories is provided:, • Auto Products, • Commercial, Institutional, • Inside the Home, Information on 15 consumer products that contain Acetyl methyl tetramethyl tetralin in the following categories is provided:, Methods of Manufacturing: It is prepared from 1, 1, 2, 4, 7-hexamethyltetralin, which is obtained by one of the following routes: 1. Reaction of alpha p-dimethylstyrene with tetramethylethene or 2, 3-dimethylbutan-2-ol in an acetic acid-sulfuric acid mixture yields the desired hexamethyltetralin, in addition to polymerized starting materials. 2. Reaction of p-cymene with 3, 3-dimethyl-l-butene (neohexene) and a tertiary alkyl halide (as a hydrogen scavenger) in the presence of catalytic amounts of anhydrous aluminum halide in inert solvents produces a high yield of the hexamethyltetralin. 1, 7-Hexamethyltetralin is subsequently acetylated to 6-acetyl-1, e.g., with acetyl chloride and aluminum chloride., Formulations, Preparations: Trade Names: Tonalide, Tetralide, Fixolide, or Extralide., U.S. Production: 2023: 17, 306 lb, 2022: 82, 287 lb, 2021: 280, 428 lb, 2020: 192, 904 lb, 2023: <50, 000 lb, 2022: <50, 2021: 50, 000 - <250, 2020: <50, Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7208], Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Ethanone, 1-(5, 6, 7, 8-tetrahydro-3, 5, 8, 8-h examethyl-2-naphthalenyl)-. National Production Volume: Withheld., Non-confidential 2016 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Ethanone, 8-h examethyl-2-naphthalenyl)-:, Table: National Aggregate Production Volume (pounds) [Table#7209], General Manufacturing Information: Other (requires additional information), All Other Chemical Product and Preparation Manufacturing, Ethanone, 8-hexamethyl-2-naphthalenyl)-: ACTIVE, ... Concentrations of HHCB (Galaxolide), AHTN (Tonalide), and HHCB-lactone (Galaxolidone) from a variety of consumer products, including perfumes, body lotions, and deodorants were measured. Concentrations of HHCB, AHTN, and HHCB-lactone in consumer products ranged from <5 ng, g to over 4000 ug, g, <5 ng, g to 451 ug, and <5 ng, g to 217 ug, respectively. The highest concentrations were found in perfumes, body creams and lotions, and deodorants. The results suggest that a wide variety of source materials exist for HHCB and AHTN, and that these materials are used on a daily basis. |
| Category | Organic Chemicals |
Documented applications: Uses: Used as fragrance for cosmetics, detergents, fabric softeners, household cleaning products, and air fresheners, [HSDB], ... used in soap and cosmetics, Used as a fragrance in cosmetics, household cleaning products and air fresheners, Use Classification: Fragrance Ingredients, Fragrance Ingredients, Cosmetics -> Masking, Industry Uses: Fragrance, Fragrance, Consumer Uses: Fragrance, Household Products: Information on 13 consumer products that contain Acetyl Hexamethyl Tetralin in the following categories is provided:, • Auto Products, • Commercial, Institutional, • Inside the Home, Information on 15 consumer products that contain Acetyl methyl tetramethyl tetralin in the following categories is provided:, Methods of Manufacturing: It is prepared from 1, 1, 2, 4, 7-hexamethyltetralin, which is obtained by one of the following routes: 1. Reaction of alpha p-dimethylstyrene with tetramethylethene or 2, 3-dimethylbutan-2-ol in an acetic acid-sulfuric acid mixture yields the desired hexamethyltetralin, in addition to polymerized starting materials. 2. Reaction of p-cymene with 3, 3-dimethyl-l-butene (neohexene) and a tertiary alkyl halide (as a hydrogen scavenger) in the presence of catalytic amounts of anhydrous aluminum halide in inert solvents produces a high yield of the hexamethyltetralin. 1, 7-Hexamethyltetralin is subsequently acetylated to 6-acetyl-1, e.g., with acetyl chloride and aluminum chloride., Formulations, Preparations: Trade Names: Tonalide, Tetralide, Fixolide, or Extralide., U.S. Production: 2023: 17, 306 lb, 2022: 82, 287 lb, 2021: 280, 428 lb, 2020: 192, 904 lb, 2023: <50, 000 lb, 2022: <50, 2021: 50, 000 - <250, 2020: <50, Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7208], Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Ethanone, 1-(5, 6, 7, 8-tetrahydro-3, 5, 8, 8-h examethyl-2-naphthalenyl)-. National Production Volume: Withheld., Non-confidential 2016 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Ethanone, 8-h examethyl-2-naphthalenyl)-:, Table: National Aggregate Production Volume (pounds) [Table#7209], General Manufacturing Information: Other (requires additional information), All Other Chemical Product and Preparation Manufacturing, Ethanone, 8-hexamethyl-2-naphthalenyl)-: ACTIVE, ... Concentrations of HHCB (Galaxolide), AHTN (Tonalide), and HHCB-lactone (Galaxolidone) from a variety of consumer products, including perfumes, body lotions, and deodorants were measured. Concentrations of HHCB, AHTN, and HHCB-lactone in consumer products ranged from <5 ng, g to over 4000 ug, g, <5 ng, g to 451 ug, and <5 ng, g to 217 ug, respectively. The highest concentrations were found in perfumes, body creams and lotions, and deodorants. The results suggest that a wide variety of source materials exist for HHCB and AHTN, and that these materials are used on a daily basis..
1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one is a carbon-based organic compound with CAS registry number 1506-02-1 and molecular formula C18H26O (molecular weight 258.4), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 1506-02-1
Its molecular formula C18H26O comprises 18 C, 26 H, 1 O atoms.
Also known as: 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one · 吐纳麝香
Category: organic chemicals
The CAS registry number of 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one is 1506-02-1.
Molecular formula C18H26O, molecular weight 258.4.
It is also registered under: 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one, 吐纳麝香.
Recorded applications: Uses: Used as fragrance for cosmetics, detergents, fabric softeners, household cleaning products, and air fresheners, [HSDB], ... used in soap and cosmetics, Used as a fragrance in cosmetics, household cleaning products and air fresheners, Use Classification: Fragrance Ingredients, Fragrance Ingredients, Cosmetics -> Masking, Industry Uses: Fragrance, Fragrance, Consumer Uses: Fragrance, Household Products: Information on 13 consumer products that contain Acetyl Hexamethyl Tetralin in the following categories is provided:, • Auto Products, • Commercial, Institutional, • Inside the Home, Information on 15 consumer products that contain Acetyl methyl tetramethyl tetralin in the following categories is provided:, Methods of Manufacturing: It is prepared from 1, 1, 2, 4, 7-hexamethyltetralin, which is obtained by one of the following routes: 1. Reaction of alpha p-dimethylstyrene with tetramethylethene or 2, 3-dimethylbutan-2-ol in an acetic acid-sulfuric acid mixture yields the desired hexamethyltetralin, in addition to polymerized starting materials. 2. Reaction of p-cymene with 3, 3-dimethyl-l-butene (neohexene) and a tertiary alkyl halide (as a hydrogen scavenger) in the presence of catalytic amounts of anhydrous aluminum halide in inert solvents produces a high yield of the hexamethyltetralin. 1, 7-Hexamethyltetralin is subsequently acetylated to 6-acetyl-1, e.g., with acetyl chloride and aluminum chloride., Formulations, Preparations: Trade Names: Tonalide, Tetralide, Fixolide, or Extralide., U.S. Production: 2023: 17, 306 lb, 2022: 82, 287 lb, 2021: 280, 428 lb, 2020: 192, 904 lb, 2023: <50, 000 lb, 2022: <50, 2021: 50, 000 - <250, 2020: <50, Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7208], Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Ethanone, 1-(5, 6, 7, 8-tetrahydro-3, 5, 8, 8-h examethyl-2-naphthalenyl)-. National Production Volume: Withheld., Non-confidential 2016 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Ethanone, 8-h examethyl-2-naphthalenyl)-:, Table: National Aggregate Production Volume (pounds) [Table#7209], General Manufacturing Information: Other (requires additional information), All Other Chemical Product and Preparation Manufacturing, Ethanone, 8-hexamethyl-2-naphthalenyl)-: ACTIVE, ... Concentrations of HHCB (Galaxolide), AHTN (Tonalide), and HHCB-lactone (Galaxolidone) from a variety of consumer products, including perfumes, body lotions, and deodorants were measured. Concentrations of HHCB, AHTN, and HHCB-lactone in consumer products ranged from <5 ng, g to over 4000 ug, g, <5 ng, g to 451 ug, and <5 ng, g to 217 ug, respectively. The highest concentrations were found in perfumes, body creams and lotions, and deodorants. The results suggest that a wide variety of source materials exist for HHCB and AHTN, and that these materials are used on a daily basis..
Category: Organic Chemicals.
Independent reference data for 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one (CAS 1506-02-1), compiled from public chemistry databases.
| CAS 号 | 1506-02-1 |
|---|---|
| PubChem CID | 89440 |
| 分子式 | C18H26O |
| IUPAC 名称 | 1-(3,5,5,6,8,8-hexamethyl-6,7-dihydronaphthalen-2-yl)ethanone |
| UNII（FDA） | 360Q8Z01IP |
| Molecular Weight | 258.4 |
|---|---|
| XLogP3 | 5.3 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 1 |
| Exact Mass | 258.198365449 |
| Monoisotopic Mass | 258.198365449 |
| Topological Polar Surface Area | 17.1 |
| Heavy Atom Count | 19 |
| Melting Point | 54.5 °C |
|---|---|
| Vapor Pressure | 0.000512 [mmHg] |
| LogP | log Kow = 5.70 |
Tonalide; 21145-77-7; Tonalid; Tetralide; AHTN; Tentarome; Musk tonalid; DTXSID7041544; AHMT (perfume); 360Q8Z01IP; DTXCID5021544; 2'-Acetonaphthone, 5',6',7',8'-tetrahydro-3',5',5',6',8',8'-hexamethyl-; RefChem:898611; 1506-02-1; 6-Acetyl-1,1,2,4,4,7-hexamethyltetralin; 1-(3,5,5,6,8,8-hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone
| GHS 通报统计 | 2.1% (38 / 1807) |
|---|
| GHS 通报统计 | 2.1% (38 / 1807) |
|---|---|
| 已通报的危害声明 | H302 (97.7%), H400 (90.7%), H410 (97.9%), H411 (23.1%), H319, H373 |
吐纳麝香 · CAS 1506-02-1 · C18H26O. UNII 360Q8Z01IP. Melting Point: 54.5 °C; Vapor Pressure: 0.000512 [mmHg]; LogP: log Kow = 5.70.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 吐纳麝香