吐纳麝香（CAS 1506-02-1）：分子式 C18H26O、分子量 258.4。
| CAS号 | 1506-02-1 |
|---|---|
| 分子式 | C18H26O |
| 分子量 | 258.4 |
| 熔点 | 54.5 °C |
| LogP | log Kow = 5.70 |
| 应用领域 | Uses: Used as fragrance for cosmetics、detergents、fabric softeners、household cleaning products、and air fresheners、[HSDB]、... used in soap and cosmetics、Used as a fragrance in cosmetics、household cleaning products and air fresheners、Use Classification: Fragrance Ingredients、Fragrance Ingredients、Cosmetics -> Masking、Industry Uses: Fragrance、Fragrance、Consumer Uses: Fragrance、Household Products: Information on 13 consumer products that contain Acetyl Hexamethyl Tetralin in the following categories is provided:、• Auto Products、• Commercial、Institutional、• Inside the Home、Information on 15 consumer products that contain Acetyl methyl tetramethyl tetralin in the following categories is provided:、Methods of Manufacturing: It is prepared from 1、1、2、4、7-hexamethyltetralin、which is obtained by one of the following routes: 1. Reaction of alpha p-dimethylstyrene with tetramethylethene or 2、3-dimethylbutan-2-ol in an acetic acid-sulfuric acid mixture yields the desired hexamethyltetralin、in addition to polymerized starting materials. 2. Reaction of p-cymene with 3、3-dimethyl-l-butene (neohexene) and a tertiary alkyl halide (as a hydrogen scavenger) in the presence of catalytic amounts of anhydrous aluminum halide in inert solvents produces a high yield of the hexamethyltetralin. 1、7-Hexamethyltetralin is subsequently acetylated to 6-acetyl-1、e.g.、with acetyl chloride and aluminum chloride.、Formulations、Preparations: Trade Names: Tonalide、Tetralide、Fixolide、or Extralide.、U.S. Production: 2023: 17、306 lb、2022: 82、287 lb、2021: 280、428 lb、2020: 192、904 lb、2023: <50、000 lb、2022: <50、2021: 50、000 - <250、2020: <50、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7208]、Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Ethanone、1-(5、6、7、8-tetrahydro-3、5、8、8-h examethyl-2-naphthalenyl)-. National Production Volume: Withheld.、Non-confidential 2016 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Ethanone、8-h examethyl-2-naphthalenyl)-:、Table: National Aggregate Production Volume (pounds) [Table#7209]、General Manufacturing Information: Other (requires additional information)、All Other Chemical Product and Preparation Manufacturing、Ethanone、8-hexamethyl-2-naphthalenyl)-: ACTIVE、... Concentrations of HHCB (Galaxolide)、AHTN (Tonalide)、and HHCB-lactone (Galaxolidone) from a variety of consumer products、including perfumes、body lotions、and deodorants were measured. Concentrations of HHCB、AHTN、and HHCB-lactone in consumer products ranged from <5 ng、g to over 4000 ug、g、<5 ng、g to 451 ug、and <5 ng、g to 217 ug、respectively. The highest concentrations were found in perfumes、body creams and lotions、and deodorants. The results suggest that a wide variety of source materials exist for HHCB and AHTN、and that these materials are used on a daily basis. |
登记用途：Uses: Used as fragrance for cosmetics、detergents、fabric softeners、household cleaning products、and air fresheners、[HSDB]、... used in soap and cosmetics、Used as a fragrance in cosmetics、household cleaning products and air fresheners、Use Classification: Fragrance Ingredients、Fragrance Ingredients、Cosmetics -> Masking、Industry Uses: Fragrance、Fragrance、Consumer Uses: Fragrance、Household Products: Information on 13 consumer products that contain Acetyl Hexamethyl Tetralin in the following categories is provided:、• Auto Products、• Commercial、Institutional、• Inside the Home、Information on 15 consumer products that contain Acetyl methyl tetramethyl tetralin in the following categories is provided:、Methods of Manufacturing: It is prepared from 1、1、2、4、7-hexamethyltetralin、which is obtained by one of the following routes: 1. Reaction of alpha p-dimethylstyrene with tetramethylethene or 2、3-dimethylbutan-2-ol in an acetic acid-sulfuric acid mixture yields the desired hexamethyltetralin、in addition to polymerized starting materials. 2. Reaction of p-cymene with 3、3-dimethyl-l-butene (neohexene) and a tertiary alkyl halide (as a hydrogen scavenger) in the presence of catalytic amounts of anhydrous aluminum halide in inert solvents produces a high yield of the hexamethyltetralin. 1、7-Hexamethyltetralin is subsequently acetylated to 6-acetyl-1、e.g.、with acetyl chloride and aluminum chloride.、Formulations、Preparations: Trade Names: Tonalide、Tetralide、Fixolide、or Extralide.、U.S. Production: 2023: 17、306 lb、2022: 82、287 lb、2021: 280、428 lb、2020: 192、904 lb、2023: <50、000 lb、2022: <50、2021: 50、000 - <250、2020: <50、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7208]、Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Ethanone、1-(5、6、7、8-tetrahydro-3、5、8、8-h examethyl-2-naphthalenyl)-. National Production Volume: Withheld.、Non-confidential 2016 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Ethanone、8-h examethyl-2-naphthalenyl)-:、Table: National Aggregate Production Volume (pounds) [Table#7209]、General Manufacturing Information: Other (requires additional information)、All Other Chemical Product and Preparation Manufacturing、Ethanone、8-hexamethyl-2-naphthalenyl)-: ACTIVE、... Concentrations of HHCB (Galaxolide)、AHTN (Tonalide)、and HHCB-lactone (Galaxolidone) from a variety of consumer products、including perfumes、body lotions、and deodorants were measured. Concentrations of HHCB、AHTN、and HHCB-lactone in consumer products ranged from <5 ng、g to over 4000 ug、g、<5 ng、g to 451 ug、and <5 ng、g to 217 ug、respectively. The highest concentrations were found in perfumes、body creams and lotions、and deodorants. The results suggest that a wide variety of source materials exist for HHCB and AHTN、and that these materials are used on a daily basis.。
吐纳麝香 是一种化工化合物，登记 CAS 号为 1506-02-1，分子式 C18H26O（分子量 258.4）。
登记 CAS 号：1506-02-1
其分子式 C18H26O 由 18 个碳、26 个氢、1 个氧 组成。
别名/同义词：吐纳麝香 · 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one
吐纳麝香 的 CAS 登记号为 1506-02-1。
分子式 C18H26O，分子量 258.4。
别名/同义词：吐纳麝香、1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one。
登记用途：Uses: Used as fragrance for cosmetics、detergents、fabric softeners、household cleaning products、and air fresheners、[HSDB]、... used in soap and cosmetics、Used as a fragrance in cosmetics、household cleaning products and air fresheners、Use Classification: Fragrance Ingredients、Fragrance Ingredients、Cosmetics -> Masking、Industry Uses: Fragrance、Fragrance、Consumer Uses: Fragrance、Household Products: Information on 13 consumer products that contain Acetyl Hexamethyl Tetralin in the following categories is provided:、• Auto Products、• Commercial、Institutional、• Inside the Home、Information on 15 consumer products that contain Acetyl methyl tetramethyl tetralin in the following categories is provided:、Methods of Manufacturing: It is prepared from 1、1、2、4、7-hexamethyltetralin、which is obtained by one of the following routes: 1. Reaction of alpha p-dimethylstyrene with tetramethylethene or 2、3-dimethylbutan-2-ol in an acetic acid-sulfuric acid mixture yields the desired hexamethyltetralin、in addition to polymerized starting materials. 2. Reaction of p-cymene with 3、3-dimethyl-l-butene (neohexene) and a tertiary alkyl halide (as a hydrogen scavenger) in the presence of catalytic amounts of anhydrous aluminum halide in inert solvents produces a high yield of the hexamethyltetralin. 1、7-Hexamethyltetralin is subsequently acetylated to 6-acetyl-1、e.g.、with acetyl chloride and aluminum chloride.、Formulations、Preparations: Trade Names: Tonalide、Tetralide、Fixolide、or Extralide.、U.S. Production: 2023: 17、306 lb、2022: 82、287 lb、2021: 280、428 lb、2020: 192、904 lb、2023: <50、000 lb、2022: <50、2021: 50、000 - <250、2020: <50、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7208]、Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Ethanone、1-(5、6、7、8-tetrahydro-3、5、8、8-h examethyl-2-naphthalenyl)-. National Production Volume: Withheld.、Non-confidential 2016 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Ethanone、8-h examethyl-2-naphthalenyl)-:、Table: National Aggregate Production Volume (pounds) [Table#7209]、General Manufacturing Information: Other (requires additional information)、All Other Chemical Product and Preparation Manufacturing、Ethanone、8-hexamethyl-2-naphthalenyl)-: ACTIVE、... Concentrations of HHCB (Galaxolide)、AHTN (Tonalide)、and HHCB-lactone (Galaxolidone) from a variety of consumer products、including perfumes、body lotions、and deodorants were measured. Concentrations of HHCB、AHTN、and HHCB-lactone in consumer products ranged from <5 ng、g to over 4000 ug、g、<5 ng、g to 451 ug、and <5 ng、g to 217 ug、respectively. The highest concentrations were found in perfumes、body creams and lotions、and deodorants. The results suggest that a wide variety of source materials exist for HHCB and AHTN、and that these materials are used on a daily basis.。
吐纳麝香（CAS 1506-02-1）的独立参考数据，整理自公开化学数据库。
| CAS 号 | 1506-02-1 |
|---|---|
| PubChem CID | 89440 |
| 分子式 | C18H26O |
| IUPAC 名称 | 1-(3,5,5,6,8,8-hexamethyl-6,7-dihydronaphthalen-2-yl)ethanone |
| UNII（FDA） | 360Q8Z01IP |
| Molecular Weight | 258.4 |
|---|---|
| XLogP3 | 5.3 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 1 |
| Exact Mass | 258.198365449 |
| Monoisotopic Mass | 258.198365449 |
| Topological Polar Surface Area | 17.1 |
| Heavy Atom Count | 19 |
| Melting Point | 54.5 °C |
|---|---|
| Vapor Pressure | 0.000512 [mmHg] |
| LogP | log Kow = 5.70 |
Tonalide; 21145-77-7; Tonalid; Tetralide; AHTN; Tentarome; Musk tonalid; DTXSID7041544; AHMT (perfume); 360Q8Z01IP; DTXCID5021544; 2'-Acetonaphthone, 5',6',7',8'-tetrahydro-3',5',5',6',8',8'-hexamethyl-; RefChem:898611; 1506-02-1; 6-Acetyl-1,1,2,4,4,7-hexamethyltetralin; 1-(3,5,5,6,8,8-hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone
| GHS 通报统计 | 2.1% (38 / 1807) |
|---|
| GHS 通报统计 | 2.1% (38 / 1807) |
|---|---|
| 已通报的危害声明 | H302 (97.7%), H400 (90.7%), H410 (97.9%), H411 (23.1%), H319, H373 |
吐纳麝香 · CAS 1506-02-1 · C18H26O. UNII 360Q8Z01IP. Melting Point: 54.5 °C; Vapor Pressure: 0.000512 [mmHg]; LogP: log Kow = 5.70.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one