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Zoledronic acid

CAS 118072-93-8C5H10N2O7P2MW 272.09

Zoledronic acid (CAS 118072-93-8) — formula C5H10N2O7P2, molecular weight 272.09; category organic chemicals.

Product Description

Zoledronic acid (CAS 118072-93-8) is a chemical raw material in the organic chemicals category. Its molecular formula C5H10N2O7P2 comprises 5 C, 10 H, 2 N, 7 O, 2 P atoms. Its molecular weight is about 272.09. Reported physicochemical data: LogP about -4.2. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.

Product Overview

CAS Number118072-93-8
Molecular FormulaC5H10N2O7P2
Molecular Weight272.09
LogP-4.2
ApplicationsUse (kg) in USA (2002): 1, Consumption (g per capita) in the USA (2002): 2.03e-06, Calculated removal (%): 22, For the treatment of hypercalcemia of malignancy. Also for the treatment of patients with multiple myeloma and patients with documented bone metastases from solid tumors, in conjunction with standard antineoplastic therapy. In May of 2007, the drug was approved for treatment of Paget's Disease
CategoryOrganic Chemicals

Applications

Documented applications: Use (kg) in USA (2002): 1, Consumption (g per capita) in the USA (2002): 2.03e-06, Calculated removal (%): 22, For the treatment of hypercalcemia of malignancy. Also for the treatment of patients with multiple myeloma and patients with documented bone metastases from solid tumors, in conjunction with standard antineoplastic therapy. In May of 2007, the drug was approved for treatment of Paget's Disease.

Technical Profile

What this product is

Zoledronic acid is a carbon-based organic compound with CAS registry number 118072-93-8 and molecular formula C5H10N2O7P2 (molecular weight 272.09), belonging to the organic chemicals segment of chemical raw materials.

Identification

CAS number: 118072-93-8

Its molecular formula C5H10N2O7P2 comprises 5 C, 10 H, 2 N, 7 O, 2 P atoms.

Also known as: Zoledronic acid · 唑来膦酸

Category: organic chemicals

Frequently Asked Questions

What is the CAS number of Zoledronic acid?

The CAS registry number of Zoledronic acid is 118072-93-8.

What is the molecular formula and molecular weight of Zoledronic acid?

Molecular formula C5H10N2O7P2, molecular weight 272.09.

What other names is Zoledronic acid known by?

It is also registered under: Zoledronic acid, 唑来膦酸.

What are the documented applications of Zoledronic acid?

Recorded applications: Use (kg) in USA (2002): 1, Consumption (g per capita) in the USA (2002): 2.03e-06, Calculated removal (%): 22, For the treatment of hypercalcemia of malignancy. Also for the treatment of patients with multiple myeloma and patients with documented bone metastases from solid tumors, in conjunction with standard antineoplastic therapy. In May of 2007, the drug was approved for treatment of Paget's Disease.

Which category does Zoledronic acid belong to?

Category: Organic Chemicals.

Packaging & documentation

Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.

PubChem Public Data

Independent reference data for Zoledronic acid (CAS 118072-93-8), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number118072-93-8
PubChem CID68740
Molecular formulaC5H10N2O7P2
IUPAC name(1-hydroxy-2-imidazol-1-yl-1-phosphonoethyl)phosphonic acid
UNII (FDA)70HZ18PH24

Computed descriptors

Molecular Weight272.09
XLogP3-4.3
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count8
Rotatable Bond Count4
Exact Mass271.99632466
Monoisotopic Mass271.99632466
Topological Polar Surface Area153
Heavy Atom Count16

Physicochemical values on record

Solubility3.27e+00 g/L
LogP-4.2

Documented uses on record

    Consumption (g per capita) in the USA (2002): 2.03e-06For the treatment of hypercalcemia of malignancy. Also for the treatment of patients with multiple myeloma and patients with documented bone metastases from solid tumors, in conjunction with standard antineoplastic therapy. In May of 2007, the drug was approved for treatment of Paget's Disease.

    Synonyms and trade names

    Zoledronic acid; 118072-93-8; Zoledronate; Zometa; Reclast; Aclasta; (1-Hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid; Zoledronic Acid Anhydrous; Anhydrous Zoledronic Acid; CGP 42446; DTXSID0042668; 70HZ18PH24; Phosphonic acid, [1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis-; ZOL 446; (1-hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acid; NSC-721517

    GHS hazard classification

    Reported hazard statementsH317 (100%), H319 (100%)

    H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]

    H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

    What the public record says

    Zoledronic acid · CAS 118072-93-8 · C5H10N2O7P2. UNII 70HZ18PH24. Solubility: 3.27e+00 g/L; LogP: -4.2.

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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