3-tert-butyl-4-hydroxyanisole

Independent reference data for 3-tert-butyl-4-hydroxyanisole (CAS 121-00-6), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Physicochemical values on record

Documented uses on record

CIR ingredient: Butylated HydroxyanisoleUsed as a food and cosmetic preservative; [Kanerva, p. 1758] Used as an antioxidant in many foods since 1947; Also used in cosmetics such as lipstick and eye shadow; [IARC]

Synonyms and trade names

25013-16-5; tert-Butyl-4-hydroxyanisole; Phenol, (1,1-dimethylethyl)-4-methoxy-; 2(3)-tert-Butyl-4-hydroxyanisole; Antrancine 12; Nipantiox 1-F; Tenox BHA; Butylohydroksyanizol; Butyl hydroxyanisole; BOA (antioxidant); Sustane 1-F; EEC No. E320; Premerge plus; Phenol, tert-butyl-4-methoxy-; DTXSID7020215; Nipantiox 1F

Regulatory listings held on file

Regulatory & Food Contact	FDA Substance added to food: ANTIMICROBIAL AGENT, ANTIOXIDANT, DOUGH STRENGTHENER, FLAVOR ENHANCER, FLOUR TRE FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS ANTIOXIDANT: Food Additives ANTIMICROBIAL AGENT, ANTIOXIDANT, DOUGH STRENGTHENER, FLAVOR ENHANCER, FLOUR TREATING AGENT, OXIDIZING OR REDU BHA JECFA ADI: 0-0.5 mg/kg bw
GHS notification summary	5.5% (47 / 847)

GHS hazard classification

GHS notification summary	5.5% (47 / 847)
Reported hazard statements	H302 (34%), H315 (52.5%), H319 (76.2%), H335 (19.8%), H351 (68.9%), H361 (18.3%), H411 (42%), H317

This chemical does not meet GHS hazard criteria for 5.5% (47 of 847) of reports.

H302 (34%): Harmful if swallowed [Warning Acute toxicity, oral]

What the public record says

3-tert-butyl-4-hydroxyanisole · CAS 121-00-6 · C11H16O2. UNII 62RAC24292. Boiling Point: 507 to 518 °F at 733 mmHg (NTP, 1992); Boiling Point: 268 °C; Melting Point: 118 to 131 °F (NTP, 1992).

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.