(1-甲基-3-苯基-5-(3-三氟甲基)苯基)-4(1H)-吡啶酮

Description

(1-Methyl-3-phenyl-5-(3-trifluoromethyl)phenyl)-4(1H)-pyridinone · CAS 59756-60-4 · C19H14F3NO. UNII 3L0JQA61JX. Melting Point: 154-155 °C; Solubility: In water, 12 mg/L at pH 7, 25 °C; Vapor Pressure: 0.0000001 [mmHg].

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• White solid; [HSDB] Colorless solid; [MSDSonline]
• White crystalline solid
• Solubility in methanol, chloroform, diethyl ether: >10 g/L; in ethyl acetate: >5 g/L; in hexane: <0.5 g/L
• Bulk density, loose: 0.358 g/cu cm; packed: 0.515 g/cu cm
• Stable to hydrolysis at pH 3-9.
• When heated to decomposition it emits toxic vapors of /nitrogen oxides, hydrogen fluoride/ ...

Regulatory Status

GHS Hazard Classification

Documented Uses

• Used as an systemic herbicide for control of aquatic weeds in ponds and lakes; No direct food uses; [Reference #1]
• 4(1H)-Pyridinone, 1-methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]-: ACTIVE
• Cotton is the only crop which has been found to be tolerant.
• In a metabolism study in rats, fluridone was rapidly and almost completely absorbed into the systemic circulation and eliminated in both the male and female rats within 3 days. The total radioactivity recovered within 3 days after dosing in the urine and feces were 78-90% and 87- 97% of administered dose in males and females, respectively. The majority (approximately 70%) of the radioactivity was eliminated via feces. No tissue accumulation was observed.
• The rates of uptake of ... (14C) fluridone (1-methyl-3-phenyl-5-(3-trifluoromethylphenyl)-4-(1H)-pyridinone) from water by rainbow trout and Chironomus tentans (4th Instar) larvae were much lower than those for more hydrophobic compounds tested under similar conditions ... Uptake and clearance of fluridone ... by chironomid larvae were more rapid than for rainbow trout. /BCF/ for chironomid larvae /was/ estimated to be 128 for fluridone ... Liver, intestine, and pyloric caeca of adult rainbow trout accumulated the
• The major metabolites were a variety of polar and non-polar compounds resulting from aromatic hydroxylations and heteroaromatic N-demethylation. The parent compound was the primary fecal component over the 1st 72 hr.

Synonyms

FLURIDONE; 59756-60-4; Brake; Pride; Sonar; EL-171; DTXSID8024107; AVAST; 1-Methyl-3-phenyl-5-(3-(trifluoromethyl)phenyl)-4(1H)-pyridinone; 1-Methyl-3-phenyl-5-(3-(trifluoromethyl)phenyl)-4-pyridone; 3L0JQA61JX; DTXCID404107; 1-Methyl-3-phenyl-5-(alpha,alpha,alpha-trifluoro-m-tolyl)-4-pyridone; RefChem:141045; 1-methyl-3-phenyl-5-(3-(trifluoromethyl)phenyl-4(1H)-pyridinone); SID144210520

Frequently Asked Questions

What are the CAS number and molecular formula of (1-Methyl-3-phenyl-5-(3-trifluoromethyl)phenyl)-4(1H)-pyridinone?

CAS 59756-60-4; molecular formula C19H14F3NO; molecular weight — g/mol.

What other names is (1-Methyl-3-phenyl-5-(3-trifluoromethyl)phenyl)-4(1H)-pyridinone known by?

FLURIDONE, 59756-60-4, Brake, Pride, Sonar, EL-171.

Is (1-Methyl-3-phenyl-5-(3-trifluoromethyl)phenyl)-4(1H)-pyridinone classified as hazardous?

1.2% of GHS notifications report no hazard classification (1 of 86).

What are the key physical properties of (1-Methyl-3-phenyl-5-(3-trifluoromethyl)phenyl)-4(1H)-pyridinone?

Melting Point: 154-155 °C; Solubility: In water, 12 mg/L at pH 7, 25 °C; Vapor Pressure: 0.0000001 [mmHg]; Vapor Pressure: 0.013 mPa (9.8X10-8 mm Hg) at 25 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.