SKATOLE (CAS 83-34-1) — formula C9H9N, molecular weight 131.17; category organic chemicals.
| CAS Number | 83-34-1 |
|---|---|
| Molecular Formula | C9H9N |
| Molecular Weight | 131.17 |
| Melting Point | 95 °C |
| Boiling Point | 265-266 °C @ 755 MM HG |
| LogP | LogP= 2.60 |
| Applications | Uses: Used in perfume fixatives, artificial civet (musk), food flavoring, and experimental veterinary medications, [HSDB], IN PERFUMERY (FIXATIVE), ARTIFICIAL CIVET, FLAVORING FOOD ADDITIVE, MEDICATION, Use Classification: Fragrance Ingredients, Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Flavoring Agents -> JECFA Flavorings Index, Methods of Manufacturing: OBTAINED BY FUSING EGG ALBUMIN WITH POTASSIUM HYDROXIDE., SYNTHESIZED...BY HEATING GLYCEROL AND ANILINE IN THE PRESENCE OF ZINC CHLORIDE, ALSO BY TREATING THE PHENYLHYDRAZONE OF PROPIONIC ALDEHYDE WITH A CALCULATED AMT OF ZINC CHLORIDE IN AN OIL BATH @ 180 °C..., ...BY CYCLIZATION OF O-TOLUIDIDES., General Manufacturing Information: 1H-Indole, 3-methyl-: ACTIVE, SKATOLE (0.001-0.1% IN THE DIET) ADVERSELY AFFECTED LARVAL GROWTH AND DEVELOPMENT AND THE SUBSEQUENT REPRODUCTIVE CAPACITY OF THE BOLLWORM, HELIOTHIS ZEA. IT IS AN ATTRACTANT FOR THE PALM WEEVIL RHYNCHOPHORUS PALMARUM AND FOR HIPPELATES EYE GNATS. ... SKATOLE HAS BEEN SHOWN TO...CAUSE, AT LEVELS OF 0.2-0.4 MG, ML, TOTAL INHIBITION OF LATERAL GROWTH BY SCLEROTINA TRIFOLIORUM, THE CLOVER ROT FUNGUS, TO EFFECT IN 100 PPM CONCN GREATER THAN 75% INHIBITION AGAINST THE RUBBER-TREE MOLDY-ROT FUNGUS MYCELIUM..., SKATOLE ACTS AS A PLANT HORMONE SHOWING AUXINIC EFFECTS IN LENS CULINARIS ROOTS AND AFFECTING SEED GERMINATION AND GROWTH OF STELLARIA MEDIA AND HYPTIS SUAVEOLENS AS WELL AS THE GROWTH OF PLANT TISSUES IN VITRO., SYNTHETIC FLAVOR INGREDIENTS- SKATOLE: FLAVOR USEFUL IN CHEESE, GRAPE, BERRY, NUT, EGG., REPORTED USES: NON-ALCOHOLIC BEVERAGES, 0.75 PPM, ICE CREAM, ICES, ETC, 1.0 PPM, CANDY, 0.78 PPM, BAKED GOODS, 0.80 PPM, GELATINS AND PUDDINGS, 0.01 PPM, CHEWING GUM, 0.10 PPM., For more General Manufacturing Information (Complete) data for 3-METHYLINDOLE (7 total), please visit the HSDB record page. |
| Category | Organic Chemicals |
Documented applications: Uses: Used in perfume fixatives, artificial civet (musk), food flavoring, and experimental veterinary medications, [HSDB], IN PERFUMERY (FIXATIVE), ARTIFICIAL CIVET, FLAVORING FOOD ADDITIVE, MEDICATION, Use Classification: Fragrance Ingredients, Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Flavoring Agents -> JECFA Flavorings Index, Methods of Manufacturing: OBTAINED BY FUSING EGG ALBUMIN WITH POTASSIUM HYDROXIDE., SYNTHESIZED...BY HEATING GLYCEROL AND ANILINE IN THE PRESENCE OF ZINC CHLORIDE, ALSO BY TREATING THE PHENYLHYDRAZONE OF PROPIONIC ALDEHYDE WITH A CALCULATED AMT OF ZINC CHLORIDE IN AN OIL BATH @ 180 °C..., ...BY CYCLIZATION OF O-TOLUIDIDES., General Manufacturing Information: 1H-Indole, 3-methyl-: ACTIVE, SKATOLE (0.001-0.1% IN THE DIET) ADVERSELY AFFECTED LARVAL GROWTH AND DEVELOPMENT AND THE SUBSEQUENT REPRODUCTIVE CAPACITY OF THE BOLLWORM, HELIOTHIS ZEA. IT IS AN ATTRACTANT FOR THE PALM WEEVIL RHYNCHOPHORUS PALMARUM AND FOR HIPPELATES EYE GNATS. ... SKATOLE HAS BEEN SHOWN TO...CAUSE, AT LEVELS OF 0.2-0.4 MG, ML, TOTAL INHIBITION OF LATERAL GROWTH BY SCLEROTINA TRIFOLIORUM, THE CLOVER ROT FUNGUS, TO EFFECT IN 100 PPM CONCN GREATER THAN 75% INHIBITION AGAINST THE RUBBER-TREE MOLDY-ROT FUNGUS MYCELIUM..., SKATOLE ACTS AS A PLANT HORMONE SHOWING AUXINIC EFFECTS IN LENS CULINARIS ROOTS AND AFFECTING SEED GERMINATION AND GROWTH OF STELLARIA MEDIA AND HYPTIS SUAVEOLENS AS WELL AS THE GROWTH OF PLANT TISSUES IN VITRO., SYNTHETIC FLAVOR INGREDIENTS- SKATOLE: FLAVOR USEFUL IN CHEESE, GRAPE, BERRY, NUT, EGG., REPORTED USES: NON-ALCOHOLIC BEVERAGES, 0.75 PPM, ICE CREAM, ICES, ETC, 1.0 PPM, CANDY, 0.78 PPM, BAKED GOODS, 0.80 PPM, GELATINS AND PUDDINGS, 0.01 PPM, CHEWING GUM, 0.10 PPM., For more General Manufacturing Information (Complete) data for 3-METHYLINDOLE (7 total), please visit the HSDB record page..
SKATOLE is a carbon-based organic compound with CAS registry number 83-34-1 and molecular formula C9H9N (molecular weight 131.17), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 83-34-1
Its molecular formula C9H9N comprises 9 C, 9 H, 1 N atoms.
Also known as: SKATOLE · 粪臭素 · 3-Methylindole
Category: organic chemicals
The CAS registry number of SKATOLE is 83-34-1.
Molecular formula C9H9N, molecular weight 131.17.
It is also registered under: SKATOLE, 粪臭素, 3-Methylindole.
Recorded applications: Uses: Used in perfume fixatives, artificial civet (musk), food flavoring, and experimental veterinary medications, [HSDB], IN PERFUMERY (FIXATIVE), ARTIFICIAL CIVET, FLAVORING FOOD ADDITIVE, MEDICATION, Use Classification: Fragrance Ingredients, Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Flavoring Agents -> JECFA Flavorings Index, Methods of Manufacturing: OBTAINED BY FUSING EGG ALBUMIN WITH POTASSIUM HYDROXIDE., SYNTHESIZED...BY HEATING GLYCEROL AND ANILINE IN THE PRESENCE OF ZINC CHLORIDE, ALSO BY TREATING THE PHENYLHYDRAZONE OF PROPIONIC ALDEHYDE WITH A CALCULATED AMT OF ZINC CHLORIDE IN AN OIL BATH @ 180 °C..., ...BY CYCLIZATION OF O-TOLUIDIDES., General Manufacturing Information: 1H-Indole, 3-methyl-: ACTIVE, SKATOLE (0.001-0.1% IN THE DIET) ADVERSELY AFFECTED LARVAL GROWTH AND DEVELOPMENT AND THE SUBSEQUENT REPRODUCTIVE CAPACITY OF THE BOLLWORM, HELIOTHIS ZEA. IT IS AN ATTRACTANT FOR THE PALM WEEVIL RHYNCHOPHORUS PALMARUM AND FOR HIPPELATES EYE GNATS. ... SKATOLE HAS BEEN SHOWN TO...CAUSE, AT LEVELS OF 0.2-0.4 MG, ML, TOTAL INHIBITION OF LATERAL GROWTH BY SCLEROTINA TRIFOLIORUM, THE CLOVER ROT FUNGUS, TO EFFECT IN 100 PPM CONCN GREATER THAN 75% INHIBITION AGAINST THE RUBBER-TREE MOLDY-ROT FUNGUS MYCELIUM..., SKATOLE ACTS AS A PLANT HORMONE SHOWING AUXINIC EFFECTS IN LENS CULINARIS ROOTS AND AFFECTING SEED GERMINATION AND GROWTH OF STELLARIA MEDIA AND HYPTIS SUAVEOLENS AS WELL AS THE GROWTH OF PLANT TISSUES IN VITRO., SYNTHETIC FLAVOR INGREDIENTS- SKATOLE: FLAVOR USEFUL IN CHEESE, GRAPE, BERRY, NUT, EGG., REPORTED USES: NON-ALCOHOLIC BEVERAGES, 0.75 PPM, ICE CREAM, ICES, ETC, 1.0 PPM, CANDY, 0.78 PPM, BAKED GOODS, 0.80 PPM, GELATINS AND PUDDINGS, 0.01 PPM, CHEWING GUM, 0.10 PPM., For more General Manufacturing Information (Complete) data for 3-METHYLINDOLE (7 total), please visit the HSDB record page..
Category: Organic Chemicals.
Independent reference data for SKATOLE (CAS 83-34-1), compiled from public chemistry databases.
| CAS Registry Number | 83-34-1 |
|---|---|
| PubChem CID | 6736 |
| Molecular formula | C9H9N |
| IUPAC name | 3-methyl-1H-indole |
| UNII (FDA) | 9W945B5H7R |
| FEMA number | 3019 |
| JECFA number | 1304 |
| Molecular Weight | 131.17 |
|---|---|
| XLogP3 | 2.6 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 0 |
| Rotatable Bond Count | 0 |
| Exact Mass | 131.073499291 |
| Monoisotopic Mass | 131.073499291 |
| Topological Polar Surface Area | 15.8 |
| Heavy Atom Count | 10 |
| Boiling Point | 265-266 °C @ 755 MM HG |
|---|---|
| Boiling Point | 265.00 to 266.00 °C. @ 755.00 mm Hg |
| Melting Point | 95 °C |
| Melting Point | 97.5 °C |
| Solubility | 0.498 mg/mL |
| Vapor Pressure | 0.0055 [mmHg] |
| Vapor Pressure | 0.0055 mm Hg |
| LogP | LogP= 2.60 |
| LogP | 2.60 |
| LogP | 2.61 |
3-METHYLINDOLE; 3-Methyl-1H-indole; Skatole; 83-34-1; Scatole; 1H-Indole, 3-methyl-; Skatol; Indole, 3-methyl-; beta-Methylindole; FEMA No. 3019; DTXSID8021775; 3-methyl-indole; SKATOLUM; 9W945B5H7R; NSC-122024; CHEBI:9171
| Regulatory & Food Contact | EU Flavoring substances FDA Substance added to food: FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT Flavoring Agents FLAVOURING_AGENT: Flavouring Agent No safety concern at current levels of intake when used as a flavouring agent TRS 928-JECFA 63/55 |
|---|---|
| GHS notification summary | 76% (304 / 400) |
| GHS notification summary | 76% (304 / 400) |
|---|---|
| Reported hazard statements | H315 (19.5%), H319 (23%), H335 (19.2%), H411 (17.5%) |
This chemical does not meet GHS hazard criteria for 76% (304 of 400) of all reports.
H315 (19.5%): Causes skin irritation [Warning Skin corrosion/irritation]
3-Methylindole · CAS 83-34-1 · C9H9N. UNII 9W945B5H7R. Boiling Point: 265-266 °C @ 755 MM HG; Boiling Point: 265.00 to 266.00 °C. @ 755.00 mm Hg; Melting Point: 95 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 3-甲基吲哚