佐芬普利钙

Description

Zofenopril calcium · CAS 81938-43-4 · C44H44CaN2O8S4. UNII 88ZQ329PU2.

Identification

CAS Registry Number	81938-43-4
PubChem CID	3033690
Molecular formula	C44H44CaN2O8S4
IUPAC name	calcium bis((2S,4S)-1-[(2S)-3-benzoylsulfanyl-2-methylpropanoyl]-4-phenylsulfanylpyrrolidine-2-carboxylate)
UNII (FDA)	88ZQ329PU2

Computed Descriptors

Molecular Weight	897.2
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	14
Exact Mass	896.1606419
Monoisotopic Mass	896.1606419
Topological Polar Surface Area	256
Heavy Atom Count	59
Formal Charge	0
Complexity	582

GHS Hazard Classification

Reported hazard statements	H400 (95.3%), H410 (95.3%)

Documented Uses

• A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.

Synonyms

ZOFENOPRIL CALCIUM; 81938-43-4; Zofenopril Calcium Salt; Zoprace; DTXSID1048625; SQ 26991; 88ZQ329PU2; SQ-26991; DTXCID8028551; CHEBI:82600; RefChem:196204; 682-603-4; Zofenopril calcium [USAN]; MFCD08704648; Zofenopril (calcium); Zofenopril calcium (USAN)

Frequently Asked Questions

What are the CAS number and molecular formula of Zofenopril calcium?

CAS 81938-43-4; molecular formula C44H44CaN2O8S4; molecular weight — g/mol.

What other names is Zofenopril calcium known by?

ZOFENOPRIL CALCIUM, 81938-43-4, Zofenopril Calcium Salt, Zoprace, DTXSID1048625, SQ 26991.

Is Zofenopril calcium classified as hazardous?

Hazard statements reported: H400, H410.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.