瓦博巴坦

Description

Vaborbactam · CAS 1360457-46-0 · C12H16BNO5S. UNII 1C75676F8V.

Identification

CAS Registry Number	1360457-46-0
PubChem CID	56649692
Molecular formula	C12H16BNO5S
IUPAC name	2-[(3R,6S)-2-hydroxy-3-[(2-thiophen-2-ylacetyl)amino]oxaborinan-6-yl]acetic acid
UNII (FDA)	1C75676F8V

Computed Descriptors

Molecular Weight	297.14
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	5
Exact Mass	297.0842240
Monoisotopic Mass	297.0842240
Topological Polar Surface Area	124
Heavy Atom Count	20
Formal Charge	0
Complexity	370

GHS Hazard Classification

Reported hazard statements	H302 (100%)

Documented Uses

• Indicated in combination with meropenem for the treatment of patients 18 years of age and older with complicated urinary tract infections (cUTI) including pyelonephritis caused by the following susceptible microorganisms: _Escherichia coli_, _Klebsiella pneumoniae_, and _Enterobacter cloacae_ species complex.
• Substances that inhibit the growth or reproduction of BACTERIA.
• Endogenous substances and drugs that inhibit or block the activity of BETA-LACTAMASES.
• Established Pharmacologic Class [EPC] - beta Lactamase Inhibitor
• Mechanisms of Action [MoA] - beta Lactamase Inhibitors
• Vaborbactam is a beta Lactamase Inhibitor. The mechanism of action of vaborbactam is as a beta Lactamase Inhibitor.

Synonyms

Vaborbactam; 1360457-46-0; RPX-7009; RPX7009; 2-[(3R,6S)-2-hydroxy-3-[(2-thiophen-2-ylacetyl)amino]oxaborinan-6-yl]acetic acid; 2-((3R,6S)-2-hydroxy-3-(2-(thiophen-2-yl)acetamido)-1,2-oxaborinan-6-yl)acetic acid; 1C75676F8V; DTXSID901027690; VABOMERE COMPONENT VABORBACTAM; 1,2-Oxaborinane-6-acetic acid, 2-hydroxy-3-((2-(2-thienyl)acetyl)amino)-, (3R,6S)-; CARBAVANCE COMPONENT VABORBACTAM; (3R,6S)-2-Hydroxy-3-[[2-(2-thienyl)acetyl]amino]-1,2-oxaborinane-6-acetic acid; 2-[(3R,6S)-2-hydroxy-3-[2-(thiophen-2-yl)acetamido]-1,2-oxaborinan-6-yl]acetic acid; vaborbactamum; (3R,6S)-2-Hydroxy-3-((2-(2-thienyl)acetyl)amino)-1,2-oxaborinane-6-acetic acid; 2-((3R,6S)-2-hydroxy-3-((2-thiophen-2-ylacetyl)amino)oxaborinan-6-yl)acetic acid

Frequently Asked Questions

What are the CAS number and molecular formula of Vaborbactam?

CAS 1360457-46-0; molecular formula C12H16BNO5S; molecular weight — g/mol.

What other names is Vaborbactam known by?

Vaborbactam, 1360457-46-0, RPX-7009, RPX7009, 2-[(3R,6S)-2-hydroxy-3-[(2-thiophen-2-ylacetyl)amino]oxaborinan-6-yl]acetic acid, 2-((3R,6S)-2-hydroxy-3-(2-(thiophen-2-yl)acetamido)-1,2-oxaborinan-6-yl)acetic acid.

Is Vaborbactam classified as hazardous?

Hazard statements reported: H302.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.