Vemurafenib (CAS 1029872-54-5) — formula C23H18ClF2N3O3S, molecular weight 489.9; category organic chemicals.
Vemurafenib (CAS 1029872-54-5) is a chemical raw material in the organic chemicals category. Its molecular formula C23H18ClF2N3O3S comprises 23 C, 18 H, 1 Cl, 2 F, 3 N, 3 O, 1 S atoms. Its molecular weight is about 489.9. Reported physicochemical data: melting point around 272°C, LogP about 5.1. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 1029872-54-5 |
|---|---|
| Molecular Formula | C23H18ClF2N3O3S |
| Molecular Weight | 489.9 |
| Melting Point | 272°C |
| LogP | 5.1 |
| Applications | Antineoplastic, MEDICATION, Formulations/Preparations: Oral: Tablets, film-coated: 240 mg, Zelboraf (Genentech) |
| Category | Organic Chemicals |
Documented applications: Antineoplastic, MEDICATION, Formulations/Preparations: Oral: Tablets, film-coated: 240 mg, Zelboraf (Genentech).
Vemurafenib is a carbon-based organic compound with CAS registry number 1029872-54-5 and molecular formula C23H18ClF2N3O3S (molecular weight 489.9), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 1029872-54-5
Its molecular formula C23H18ClF2N3O3S comprises 23 C, 18 H, 1 Cl, 2 F, 3 N, 3 O, 1 S atoms.
Also known as: Vemurafenib · 维莫非尼
Category: organic chemicals
The CAS registry number of Vemurafenib is 1029872-54-5.
Molecular formula C23H18ClF2N3O3S, molecular weight 489.9.
It is also registered under: Vemurafenib, 维莫非尼.
Recorded applications: Antineoplastic, MEDICATION, Formulations/Preparations: Oral: Tablets, film-coated: 240 mg, Zelboraf (Genentech).
Category: Organic Chemicals.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for Vemurafenib (CAS 1029872-54-5), compiled from public chemistry databases.
| CAS Registry Number | 1029872-54-5 |
|---|---|
| PubChem CID | 42611257 |
| Molecular formula | C23H18ClF2N3O3S |
| IUPAC name | N-[3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]propane-1-sulfonamide |
| UNII (FDA) | 207SMY3FQT |
| Molecular Weight | 489.9 |
|---|---|
| XLogP3 | 5 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 7 |
| Exact Mass | 489.0725466 |
| Monoisotopic Mass | 489.0725466 |
| Topological Polar Surface Area | 100 |
| Heavy Atom Count | 33 |
| Melting Point | 272°C |
|---|---|
| Solubility | <1 mg/mL |
| LogP | 5.1 |
| Dissociation Constants | 7.1 |
Vemurafenib; 918504-65-1; Zelboraf; PLX-4032; PLX 4032; RG7204; RG 7204; RO 5185426; 207SMY3FQT; vemurafenibum; N-(3-{[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide; RG-7204; Ro 51-85426; RO-5185426; RO-51-85426; CHEBI:63637
| Reported hazard statements | H410 (100%), H302 (100%), H350 (100%), H361 (100%), H373 (100%), H413 (100%) |
|---|
H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]
P273, P391, and P501 (click each P-code to see the statement)
Vemurafenib · CAS 1029872-54-5 · C23H18ClF2N3O3S. UNII 207SMY3FQT. Melting Point: 272°C; Solubility: <1 mg/mL; LogP: 5.1.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 维莫非尼