thalidomide (CAS 50-35-1) — formula C13H10N2O4, molecular weight 258.23; category organic chemicals.
| CAS Number | 50-35-1 |
|---|---|
| Molecular Formula | C13H10N2O4 |
| Molecular Weight | 258.23 |
| Melting Point | 516 to 520 °F (NTP, 1992) |
| LogP | 0.33 |
| Applications | Uses: MEDICATION, Angiogenesis Inhibitors, Immunosuppressive Agents, Leprostatic Agents, Teratogens, For the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). Also for use as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence. Used to treat multiple myeloma., Methods of Manufacturing: Preparation: United Kingdom patent 768821 (1957 to Chemie Grunenthal), Formulations, Preparations: Thalidomide was first marketed in Germany 1957 under the name Contergan, in the UK in 1958 as Distaval, and finally at least under 35 further names worldwide., Table: Thalidomide Preparations [Table#4648], General Manufacturing Information: Thalidomide is commercially available as a 1:1 racemic mixture of the 2 enantiomers with a net optical rotation of zero. |
| Category | Organic Chemicals |
Documented applications: Uses: MEDICATION, Angiogenesis Inhibitors, Immunosuppressive Agents, Leprostatic Agents, Teratogens, For the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). Also for use as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence. Used to treat multiple myeloma., Methods of Manufacturing: Preparation: United Kingdom patent 768821 (1957 to Chemie Grunenthal), Formulations, Preparations: Thalidomide was first marketed in Germany 1957 under the name Contergan, in the UK in 1958 as Distaval, and finally at least under 35 further names worldwide., Table: Thalidomide Preparations [Table#4648], General Manufacturing Information: Thalidomide is commercially available as a 1:1 racemic mixture of the 2 enantiomers with a net optical rotation of zero..
thalidomide is a carbon-based organic compound with CAS registry number 50-35-1 and molecular formula C13H10N2O4 (molecular weight 258.23), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 50-35-1
Its molecular formula C13H10N2O4 comprises 13 C, 10 H, 2 N, 4 O atoms.
Also known as: thalidomide · 沙利度胺
Category: organic chemicals
The CAS registry number of thalidomide is 50-35-1.
Molecular formula C13H10N2O4, molecular weight 258.23.
It is also registered under: thalidomide, 沙利度胺.
Recorded applications: Uses: MEDICATION, Angiogenesis Inhibitors, Immunosuppressive Agents, Leprostatic Agents, Teratogens, For the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). Also for use as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence. Used to treat multiple myeloma., Methods of Manufacturing: Preparation: United Kingdom patent 768821 (1957 to Chemie Grunenthal), Formulations, Preparations: Thalidomide was first marketed in Germany 1957 under the name Contergan, in the UK in 1958 as Distaval, and finally at least under 35 further names worldwide., Table: Thalidomide Preparations [Table#4648], General Manufacturing Information: Thalidomide is commercially available as a 1:1 racemic mixture of the 2 enantiomers with a net optical rotation of zero..
Category: Organic Chemicals.
Independent reference data for thalidomide (CAS 50-35-1), compiled from public chemistry databases.
| CAS Registry Number | 50-35-1 |
|---|---|
| PubChem CID | 5426 |
| Molecular formula | C13H10N2O4 |
| IUPAC name | 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione |
| UNII (FDA) | 4Z8R6ORS6L |
| Molecular Weight | 258.23 |
|---|---|
| XLogP3 | 0.3 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 1 |
| Exact Mass | 258.06405680 |
| Monoisotopic Mass | 258.06405680 |
| Topological Polar Surface Area | 83.6 |
| Heavy Atom Count | 19 |
| Melting Point | 516 to 520 °F (NTP, 1992) |
|---|---|
| Melting Point | 270 |
| Melting Point | 270 °C |
| Solubility | 545 |
| Solubility | 2.55e+00 g/L |
| LogP | 0.33 |
| LogP | log Kow = 0.33 |
| LogP | 0.3 |
| LogP | 0.49 |
thalidomide; 50-35-1; Thalomid; Contergan; Pantosediv; Distaval; Softenon; Kevadon; Psychotablets; Algosediv; Calmorex; Neosedyn; Profarmil; Quetimid; Sedisperil; Imidene
| Reported hazard statements | H302 (88.2%), H360 (92.1%) |
|---|
H302 (88.2%): Harmful if swallowed [Warning Acute toxicity, oral]
H360 (92.1%): May damage fertility or the unborn child [Danger Reproductive toxicity]
thalidomide · CAS 50-35-1 · C13H10N2O4. UNII 4Z8R6ORS6L. Melting Point: 516 to 520 °F (NTP, 1992); Melting Point: 270; Melting Point: 270 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 沙利度胺