tolazamide (CAS 1156-19-0) — formula C14H21N3O3S, molecular weight 311.40; category organic chemicals.
tolazamide (CAS 1156-19-0) is a chemical raw material in the organic chemicals category. Its molecular formula C14H21N3O3S comprises 14 C, 21 H, 3 N, 3 O, 1 S atoms. Its molecular weight is about 311.40. Reported physicochemical data: melting point around 170-173 °C, LogP about 2.69. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 1156-19-0 |
|---|---|
| Molecular Formula | C14H21N3O3S |
| Molecular Weight | 311.40 |
| Melting Point | 170-173 °C |
| LogP | 2.69 |
| Applications | Therap cat: Antidiabetic, An orally effective hypoglycemic drug, For use as an adjunct to diet to lower the blood glucose in patients with non-insulin dependent diabetes mellitus (Type II) whose hyperglycemia cannot be satisfactorily controlled by diet alone, Methods of Manufacturing: Prepn: Wright, Willette, J Med Pharm Chem 5 |
| Category | Organic Chemicals |
Documented applications: Therap cat: Antidiabetic, An orally effective hypoglycemic drug, For use as an adjunct to diet to lower the blood glucose in patients with non-insulin dependent diabetes mellitus (Type II) whose hyperglycemia cannot be satisfactorily controlled by diet alone, Methods of Manufacturing: Prepn: Wright, Willette, J Med Pharm Chem 5.
tolazamide is a carbon-based organic compound with CAS registry number 1156-19-0 and molecular formula C14H21N3O3S (molecular weight 311.40), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 1156-19-0
Its molecular formula C14H21N3O3S comprises 14 C, 21 H, 3 N, 3 O, 1 S atoms.
Also known as: tolazamide · 妥拉磺酰胺
Category: organic chemicals
The CAS registry number of tolazamide is 1156-19-0.
Molecular formula C14H21N3O3S, molecular weight 311.40.
It is also registered under: tolazamide, 妥拉磺酰胺.
Recorded applications: Therap cat: Antidiabetic, An orally effective hypoglycemic drug, For use as an adjunct to diet to lower the blood glucose in patients with non-insulin dependent diabetes mellitus (Type II) whose hyperglycemia cannot be satisfactorily controlled by diet alone, Methods of Manufacturing: Prepn: Wright, Willette, J Med Pharm Chem 5.
Category: Organic Chemicals.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for tolazamide (CAS 1156-19-0), compiled from public chemistry databases.
| CAS Registry Number | 1156-19-0 |
|---|---|
| PubChem CID | 5503 |
| Molecular formula | C14H21N3O3S |
| IUPAC name | 1-(azepan-1-yl)-3-(4-methylphenyl)sulfonylurea |
| UNII (FDA) | 9LT1BRO48Q |
| Molecular Weight | 311.40 |
|---|---|
| XLogP3 | 1.5 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 311.13036271 |
| Monoisotopic Mass | 311.13036271 |
| Topological Polar Surface Area | 86.9 |
| Heavy Atom Count | 21 |
| Melting Point | 170-173 °C |
|---|---|
| Melting Point | 170 - 173 °C |
| Solubility | 65.4 |
| Solubility | In water, 65.4 mg/l @ 30 °C |
| Solubility | 3.08e-01 g/L |
| LogP | 2.69 |
| LogP | log Kow= 2.69 |
| LogP | 2.5 |
| LogP | 2.34 |
| Dissociation Constants | PKA @ 25 °C, 3.6; PKA @ 37.5 °C, 5.68 |
tolazamide; 1156-19-0; Tolinase; Norglycin; Tolanase; Tolazolamide; Diabewas; Tolazamida; Tolazamidum; 1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea; NSC-70762; 1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea; U-17835; N-(p-Toluenesulfonyl)-N'-hexamethyleniminourea; NCI-C03327; 4-(p-Tolylsulfonyl)-1,1-hexamethylenesemicarbazide
| GHS notification summary | 50% (1 / 2) |
|---|
| GHS notification summary | 50% (1 / 2) |
|---|---|
| Reported hazard statements | H370 (50%) |
This chemical does not meet GHS hazard criteria for 50% (1 of 2) of reports.
H370 (50%): Causes damage to organs [Danger Specific target organ toxicity, single exposure]
tolazamide · CAS 1156-19-0 · C14H21N3O3S. UNII 9LT1BRO48Q. Melting Point: 170-173 °C; Melting Point: 170 - 173 °C; Solubility: 65.4.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 妥拉磺酰胺