妥拉磺酰胺

Name: 妥拉磺酰胺
Brand: 济南圣和化工有限公司

CAS 1156-19-0C14H21N3O3SMW 311.40

妥拉磺酰胺（CAS 1156-19-0）属有机化学品类产品，分子式 C14H21N3O3S，分子量 311.40。济南圣和化工有限公司常年现货供应该产品，常规纯度按批次COA提供(不公开发布)，可按客户需求安排分装包装，欢迎邮件或来电询价。

产品概览

CAS号	1156-19-0
分子式	C14H21N3O3S
分子量	311.40
熔点	170-173 °C
LogP	2.69
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	有机化学品
类别	有机化学品

应用领域

有机化学品

妥拉磺酰胺在有机化学品领域使用广泛。采购前请确认纯度等级与包装形式，以批次 COA 为验收依据。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

采购提示：本产品按按订单/批次确认(不公开发布)起订发货，收到货物后请先核对包装完好性再行入库。储存条件为阴凉干燥、密封保存；如需 MSDS 或运输说明，可在询价时一并索取。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

作为化工原料供应服务商，济南圣和化工有限公司长期服务于化工贸易、食品添加、医药中间体、日化原料等行业的采购需求。除妥拉磺酰胺外，您还可以在站内按 CAS 号或产品分类检索更多品类，获取规格与报价。

常见问题

妥拉磺酰胺的 CAS 号是多少？

妥拉磺酰胺的 CAS 号为 1156-19-0。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

妥拉磺酰胺有什么用途？

主要应用于有机化学品。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

tolazamide · CAS 1156-19-0 · C14H21N3O3S. UNII 9LT1BRO48Q. Melting Point: 170-173 °C; Melting Point: 170 - 173 °C; Solubility: 65.4.

Identification

CAS Registry Number	1156-19-0
PubChem CID	5503
Molecular formula	C14H21N3O3S
IUPAC name	1-(azepan-1-yl)-3-(4-methylphenyl)sulfonylurea
UNII (FDA)	9LT1BRO48Q

Computed Descriptors

Molecular Weight	311.40
XLogP3	1.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	311.13036271
Monoisotopic Mass	311.13036271
Topological Polar Surface Area	86.9
Heavy Atom Count	21
Formal Charge	0

Physical & Chemical Properties

Melting Point	170-173 °C
Melting Point	170 - 173 °C
Solubility	65.4
Solubility	In water, 65.4 mg/l @ 30 °C
Solubility	3.08e-01 g/L
LogP	2.69
LogP	log Kow= 2.69
LogP	2.5
LogP	2.34
Dissociation Constants	PKA @ 25 °C, 3.6; PKA @ 37.5 °C, 5.68

Physical description & handling notes

Tolazamide appears as white to off-white crystalline powder. Odorless or with a slight odor. (NTP, 1992)
Solid
Crystals
WHITE TO OFF-WHITE, CRYSTALLINE POWDER
ODORLESS OR HAS SLIGHT ODOR
322 to 336 °F (with decomposition) (NTP, 1992)

Regulatory Status

GHS notification summary	50% (1 / 2)

GHS Hazard Classification

GHS notification summary	50% (1 / 2)
Reported hazard statements	H370 (50%)

This chemical does not meet GHS hazard criteria for 50% (1 of 2) of reports.

H370 (50%): Causes damage to organs [Danger Specific target organ toxicity, single exposure]

Documented Uses

An orally effective hypoglycemic drug.
For use as an adjunct to diet to lower the blood glucose in patients with non-insulin dependent diabetes mellitus (Type II) whose hyperglycemia cannot be satisfactorily controlled by diet alone.
Prepn: Wright, Willette, J Med Pharm Chem 5, 815 (1962); Wright, British patent 887,886 (1962 to Upjohn).
METHYL P-TOLYLSULFONYLCARBAMATE IS CAUSED TO UNDERGO AMMONOLYSIS TYPE OF REACTION WITH 1-AMINOHEXAMETHYLENEIMINE, US PATENT 3,063,903.
Breast Feeding; Lactation; Milk, Human; Hypoglycemic Agents; Sulfonylurea Compounds
...THIS POTENT AGENT LACKS ANTIDIURETIC ACTION & MAY BE ESPECIALLY USEFUL IN TREATMENT OF PT WHO HAVE TENDENCY TO RETAIN WATER.

Synonyms

tolazamide; 1156-19-0; Tolinase; Norglycin; Tolanase; Tolazolamide; Diabewas; Tolazamida; Tolazamidum; 1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea; NSC-70762; 1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea; U-17835; N-(p-Toluenesulfonyl)-N'-hexamethyleniminourea; NCI-C03327; 4-(p-Tolylsulfonyl)-1,1-hexamethylenesemicarbazide

Frequently Asked Questions

What are the CAS number and molecular formula of tolazamide?

CAS 1156-19-0; molecular formula C14H21N3O3S; molecular weight — g/mol.

What other names is tolazamide known by?

tolazamide, 1156-19-0, Tolinase, Norglycin, Tolanase, Tolazolamide.

Is tolazamide classified as hazardous?

50% of GHS notifications report no hazard classification (1 of 2).

What are the key physical properties of tolazamide?

Melting Point: 170-173 °C; Melting Point: 170 - 173 °C; Solubility: 65.4; Solubility: In water, 65.4 mg/l @ 30 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.