盐酸螺普利

Description

Spirapril Hydrochloride · CAS 94841-17-5 · C22H31ClN2O5S2. UNII OCC25LM897.

Identification

CAS Registry Number	94841-17-5
PubChem CID	6850814
Molecular formula	C22H31ClN2O5S2
IUPAC name	(8S)-7-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid;hydrochloride
UNII (FDA)	OCC25LM897

Computed Descriptors

Molecular Weight	503.1
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	10
Exact Mass	502.1362921
Monoisotopic Mass	502.1362921
Topological Polar Surface Area	147
Heavy Atom Count	32
Formal Charge	0
Complexity	650

Documented Uses

• A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.

Synonyms

Spirapril hydrochloride; 94841-17-5; Spirapril HCl; Renormax; Sch 33844; DTXSID6044272; OCC25LM897; Sch-33844; DTXCID4024272; RefChem:57301; Spirapril hydrochloride [USAN]; Spirapril hydrochloride (USAN); Spirapril for system suitability CRS; UNII-OCC25LM897; 83647-97-6 (free base); Renormax (TN)

Frequently Asked Questions

What are the CAS number and molecular formula of Spirapril Hydrochloride?

CAS 94841-17-5; molecular formula C22H31ClN2O5S2; molecular weight — g/mol.

What other names is Spirapril Hydrochloride known by?

Spirapril hydrochloride, 94841-17-5, Spirapril HCl, Renormax, Sch 33844, DTXSID6044272.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.