Sorafenib (CAS 284461-73-0) — formula C21H16ClF3N4O3, molecular weight 464.8; category organic chemicals.
Sorafenib (CAS 284461-73-0) is a organic chemicals. Its molecular formula C21H16ClF3N4O3 comprises 21 C, 16 H, 1 Cl, 3 F, 4 N, 3 O atoms. Its molecular weight is about 464.8. Reported physicochemical data: melting point around 187-226, LogP about 3.8. Organic chemicals are the largest family of carbon-based compounds, widely used across pharmaceuticals, agrochemicals, materials, cosmetics and food industries. Downstream uses span pharmaceutical ingredients, agrochemicals, dyes, solvents, surfactants, food additives and polymer materials. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 284461-73-0 |
|---|---|
| Molecular Formula | C21H16ClF3N4O3 |
| Molecular Weight | 464.8 |
| Melting Point | 187-226 |
| LogP | 3.8 |
| Applications | Antineoplastic Agents, Protein Kinase Inhibitors, THERAPEUTIC CATEGORY: Antineoplastic, MEDICATION, Use (kg, approx.) in Germany (2009): >250 |
| Category | Organic Chemicals |
Documented applications: Antineoplastic Agents, Protein Kinase Inhibitors, THERAPEUTIC CATEGORY: Antineoplastic, MEDICATION, Use (kg, approx.) in Germany (2009): >250.
Sorafenib is a carbon-based organic compound with CAS registry number 284461-73-0 and molecular formula C21H16ClF3N4O3 (molecular weight 464.8), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 284461-73-0
Its molecular formula C21H16ClF3N4O3 comprises 21 C, 16 H, 1 Cl, 3 F, 4 N, 3 O atoms.
Also known as: Sorafenib · 索拉非尼
Category: organic chemicals
The CAS registry number of Sorafenib is 284461-73-0.
Molecular formula C21H16ClF3N4O3, molecular weight 464.8.
It is also registered under: Sorafenib, 索拉非尼.
Recorded applications: Antineoplastic Agents, Protein Kinase Inhibitors, THERAPEUTIC CATEGORY: Antineoplastic, MEDICATION, Use (kg, approx.) in Germany (2009): >250.
Category: Organic Chemicals.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for Sorafenib (CAS 284461-73-0), compiled from public chemistry databases.
| CAS Registry Number | 284461-73-0 |
|---|---|
| PubChem CID | 216239 |
| Molecular formula | C21H16ClF3N4O3 |
| IUPAC name | 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide |
| UNII (FDA) | 9ZOQ3TZI87 |
| Molecular Weight | 464.8 |
|---|---|
| XLogP3 | 4.1 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 5 |
| Exact Mass | 464.0863026 |
| Monoisotopic Mass | 464.0863026 |
| Topological Polar Surface Area | 92.4 |
| Heavy Atom Count | 32 |
| Melting Point | 187-226 |
|---|---|
| Melting Point | 205.6 °C |
| Solubility | < 0.01 g/L |
| Solubility | 1.71e-03 g/L |
| LogP | 3.8 |
Sorafenib; 284461-73-0; BAY 43-9006; sorafenibum; 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide; 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide; 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide; DTXSID7041128; BAY-43-9006; N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea; 9ZOQ3TZI87; 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide; BAY 439006; BAY-439006; CHEBI:50924; L01XE05
| Reported hazard statements | H351 (40%), H360 (40%), H361 (40%), H362 (60%), H372 (60%), H400 (40%), H402 (20%), H410 (60%) |
|---|
H351 (40%): Suspected of causing cancer [Warning Carcinogenicity]
H360 (40%): May damage fertility or the unborn child [Danger Reproductive toxicity]
Sorafenib · CAS 284461-73-0 · C21H16ClF3N4O3. UNII 9ZOQ3TZI87. Melting Point: 187-226; Melting Point: 205.6 °C; Solubility: < 0.01 g/L.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 索拉非尼