谷美辛前体

Description

proglumetacin · CAS 57132-53-3 · C46H58ClN5O8. UNII FV919079LU.

Identification

CAS Registry Number	57132-53-3
PubChem CID	4921
Molecular formula	C46H58ClN5O8
IUPAC name	3-[4-[2-[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl]oxyethyl]piperazin-1-yl]propyl 4-benzamido-5-(dipropylamino)-5-oxopentanoate
UNII (FDA)	FV919079LU

Computed Descriptors

Molecular Weight	844.4
XLogP3	7.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	23
Exact Mass	843.3973915
Monoisotopic Mass	843.3973915
Topological Polar Surface Area	140
Heavy Atom Count	60
Formal Charge	0

Documented Uses

• Use (kg; approx.) in Germany (2009): >500
• Consumption (g per capita; approx.) in Germany (2009): 0.00611
• Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
• M01 - Antiinflammatory and antirheumatic products
• M01A - Antiinflammatory and antirheumatic products, non-steroids
• M01AB - Acetic acid derivatives and related substances

Synonyms

PROGLUMETACIN; 57132-53-3; Proglumetacina; Proglumetacine; Proglumetacinum; DTXSID0048842; FV919079LU; DTXCID3028768; CHEBI:76263; RefChem:176175; M01AB14; Proglumetacin (INN); NCGC00183024-01; PROGLUMETACIN [INN]; Proglumetacin [INN:BAN]; Proglumetacine [INN-French]

Frequently Asked Questions

What are the CAS number and molecular formula of proglumetacin?

CAS 57132-53-3; molecular formula C46H58ClN5O8; molecular weight — g/mol.

What other names is proglumetacin known by?

PROGLUMETACIN, 57132-53-3, Proglumetacina, Proglumetacine, Proglumetacinum, DTXSID0048842.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.