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Pemigatinib

CAS 1513857-77-6C24H27F2N5O4MW 487.5

Pemigatinib (CAS 1513857-77-6) — formula C24H27F2N5O4, molecular weight 487.5; category organic chemicals.

Product Description

Pemigatinib (CAS 1513857-77-6) is a chemical raw material in the organic chemicals category. Its molecular formula C24H27F2N5O4 comprises 24 C, 27 H, 2 F, 5 N, 4 O atoms. Its molecular weight is about 487.5. Reported physicochemical data: LogP about 1.8. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.

Product Overview

CAS Number1513857-77-6
Molecular FormulaC24H27F2N5O4
Molecular Weight487.5
LogP1.8
CategoryOrganic Chemicals

Technical Profile

What this product is

Pemigatinib is a carbon-based organic compound with CAS registry number 1513857-77-6 and molecular formula C24H27F2N5O4 (molecular weight 487.5), belonging to the organic chemicals segment of chemical raw materials.

Identification

CAS number: 1513857-77-6

Its molecular formula C24H27F2N5O4 comprises 24 C, 27 H, 2 F, 5 N, 4 O atoms.

Also known as: Pemigatinib · 培米加替尼

Category: organic chemicals

Frequently Asked Questions

What is the CAS number of Pemigatinib?

The CAS registry number of Pemigatinib is 1513857-77-6.

What is the molecular formula and molecular weight of Pemigatinib?

Molecular formula C24H27F2N5O4, molecular weight 487.5.

What other names is Pemigatinib known by?

It is also registered under: Pemigatinib, 培米加替尼.

Which category does Pemigatinib belong to?

Category: Organic Chemicals.

Packaging & documentation

Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.

PubChem Public Data

Independent reference data for Pemigatinib (CAS 1513857-77-6), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number1513857-77-6
PubChem CID86705695
Molecular formulaC24H27F2N5O4
IUPAC name11-(2,6-difluoro-3,5-dimethoxyphenyl)-13-ethyl-4-(morpholin-4-ylmethyl)-5,7,11,13-tetrazatricyclo[7.4.0.02,6]trideca-1,3,6,8-tetraen-12-one
UNII (FDA)Y6BX7BL23K

Computed descriptors

Molecular Weight487.5
XLogP31.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count6
Exact Mass487.20311068
Monoisotopic Mass487.20311068
Topological Polar Surface Area83.2
Heavy Atom Count35

Documented uses on record

    Pemigatinib is indicated for the treatment of unresectable locally advanced or metastatic cholangiocarcinoma in previously-treated adult patients with a fibroblast growth factor receptor 2 (FGFR2) fusion or other rearrangement as detected by an FDA-approved test. It is also indicated for the treatment of adults with relapsed or refractory myeloid/lymphoid neoplasms (MLNs) with FGFR1 rearrangement.Pemigatinib is a fibroblast growth factor (FGF) receptor kinase inhibitor that is used to treat unresectable, locally advanced or metastatic intrahepatic cholangiocarcinoma, as well as myeloid or lymphoid neoplasms with FGFR rearrangements. Pemigatinib is associated with transient and usually mild-to-moderate elevations in serum aminotransferase levels during therapy, but has not been convincingly linked to cases of clinically apparent liver injury with jaundice.

    Synonyms and trade names

    Pemigatinib; 1513857-77-6; Pemazyre; INCB054828; Fgfr inhibitor INCB054828; Y6BX7BL23K; INCB-054828; DTXSID501027955; pemigatinibum; RefChem:58318; DTXCID401513523; Pemigatinib [INN]; Pemigatinib [USAN]; INCB54828; INCB-54828; UNII-Y6BX7BL23K

    What the public record says

    Pemigatinib · CAS 1513857-77-6 · C24H27F2N5O4. UNII Y6BX7BL23K.

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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Supplier: Jinan Shenghe Chemical Co., Ltd.

中文页面: 培米加替尼

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