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primaquine

CAS 90-34-6C15H21N3OMW 259.35

primaquine (CAS 90-34-6) — formula C15H21N3O, molecular weight 259.35; category organic chemicals.

Product Description

primaquine (CAS 90-34-6) is a chemical raw material in the organic chemicals category. Its molecular formula C15H21N3O comprises 15 C, 21 H, 3 N, 1 O atoms. Its molecular weight is about 259.35. Reported physicochemical data: melting point around < 25 °C, boiling point around 177, LogP about 2.1. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.

Product Overview

CAS Number90-34-6
Molecular FormulaC15H21N3O
Molecular Weight259.35
Melting Point< 25 °C
Boiling Point177
LogP2.1
ApplicationsMEDICATION, Antimalarial, Methods of Manufacturing: Synthesis: 6-Methoxy-8-aminoquinoline is condensed with 1-phthalimido-4-bromopentane, and the phthalyl group is cleaved by heating with hydrazine in ethanol and hydrochloric acid, Formulations/Preparations: Primaquine phosphate tablets 15 mg (of primaquine)
CategoryOrganic Chemicals

Applications

Documented applications: MEDICATION, Antimalarial, Methods of Manufacturing: Synthesis: 6-Methoxy-8-aminoquinoline is condensed with 1-phthalimido-4-bromopentane, and the phthalyl group is cleaved by heating with hydrazine in ethanol and hydrochloric acid, Formulations/Preparations: Primaquine phosphate tablets 15 mg (of primaquine).

Technical Profile

What this product is

primaquine is a carbon-based organic compound with CAS registry number 90-34-6 and molecular formula C15H21N3O (molecular weight 259.35), belonging to the organic chemicals segment of chemical raw materials.

Identification

CAS number: 90-34-6

Its molecular formula C15H21N3O comprises 15 C, 21 H, 3 N, 1 O atoms.

Also known as: primaquine · 伯氨喹

Category: organic chemicals

Frequently Asked Questions

What is the CAS number of primaquine?

The CAS registry number of primaquine is 90-34-6.

What is the molecular formula and molecular weight of primaquine?

Molecular formula C15H21N3O, molecular weight 259.35.

What other names is primaquine known by?

It is also registered under: primaquine, 伯氨喹.

What are the documented applications of primaquine?

Recorded applications: MEDICATION, Antimalarial, Methods of Manufacturing: Synthesis: 6-Methoxy-8-aminoquinoline is condensed with 1-phthalimido-4-bromopentane, and the phthalyl group is cleaved by heating with hydrazine in ethanol and hydrochloric acid, Formulations/Preparations: Primaquine phosphate tablets 15 mg (of primaquine).

Which category does primaquine belong to?

Category: Organic Chemicals.

Packaging & documentation

Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.

PubChem Public Data

Independent reference data for primaquine (CAS 90-34-6), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number90-34-6
PubChem CID4908
Molecular formulaC15H21N3O
IUPAC name4-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine
UNII (FDA)MVR3634GX1

Computed descriptors

Molecular Weight259.35
XLogP32.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass259.168462302
Monoisotopic Mass259.168462302
Topological Polar Surface Area60.2
Heavy Atom Count19

Physicochemical values on record

Boiling Point177
Boiling Point175-179 °C
Melting Point< 25 °C
Solubility5.64e-02 g/L
LogP2.1
Dissociation Constants10.03

Documented uses on record

    Synthesis: 6-Methoxy-8-aminoquinoline is condensed with 1-phthalimido-4-bromopentane, and the phthalyl group is cleaved by heating with hydrazine in ethanol and hydrochloric acid.Primaquine is an aminoquinoline that has been used for the prevention and therapy of malaria for more than 50 years. Primaquine is not associated with serum enzyme elevations during therapy and has yet to be linked to instances of clinically apparent acute liver injury.

    Synonyms and trade names

    PRIMAQUINE; 90-34-6; Primachin; 8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline; Neo-Quipenyl; Primaquin; Primachinum; Primaquina; Primaquinum; Kanaprim; Primachina; 1,4-Pentanediamine, N4-(6-methoxy-8-quinolinyl)-; 4-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine; Maliride; 6-Methoxy-8-(4-amino-1-methylbutylamino)quinoline; N-(5-aminopentan-2-yl)-6-methoxyquinolin-8-amine

    GHS hazard classification

    Reported hazard statementsH301 (100%)

    H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

    H361d (100%): Suspected of damaging the unborn child [Warning Reproductive toxicity]

    What the public record says

    primaquine · CAS 90-34-6 · C15H21N3O. UNII MVR3634GX1. Boiling Point: 177; Boiling Point: 175-179 °C; Melting Point: < 25 °C.

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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