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Pazopanib

CAS 444731-52-6C21H23N7O2SMW 437.5

Pazopanib (CAS 444731-52-6) — formula C21H23N7O2S, molecular weight 437.5; category organic chemicals.

Product Description

Pazopanib (CAS 444731-52-6) is a organic chemicals. Its molecular formula C21H23N7O2S comprises 21 C, 23 H, 7 N, 2 O, 1 S atoms. Its molecular weight is about 437.5. Reported physicochemical data: LogP about 3.3. Organic chemicals are the largest family of carbon-based compounds, widely used across pharmaceuticals, agrochemicals, materials, cosmetics and food industries. Downstream uses span pharmaceutical ingredients, agrochemicals, dyes, solvents, surfactants, food additives and polymer materials. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.

Product Overview

CAS Number444731-52-6
Molecular FormulaC21H23N7O2S
Molecular Weight437.5
LogP3.3
ApplicationsMEDICATION, THERAPEUTIC CATEGORY: Antineoplastic, Methods of Manufacturing: Preparation: A. Boloor et al, World Intellectual Property Organization patent 02059110 (2002 to Glaxo), eidem, United States of America patent 7105530 (2006 to SKB)
CategoryOrganic Chemicals

Applications

Documented applications: MEDICATION, THERAPEUTIC CATEGORY: Antineoplastic, Methods of Manufacturing: Preparation: A. Boloor et al, World Intellectual Property Organization patent 02059110 (2002 to Glaxo), eidem, United States of America patent 7105530 (2006 to SKB).

Technical Profile

What this product is

Pazopanib is a carbon-based organic compound with CAS registry number 444731-52-6 and molecular formula C21H23N7O2S (molecular weight 437.5), belonging to the organic chemicals segment of chemical raw materials.

Identification

CAS number: 444731-52-6

Its molecular formula C21H23N7O2S comprises 21 C, 23 H, 7 N, 2 O, 1 S atoms.

Also known as: Pazopanib · 帕唑帕尼

Category: organic chemicals

Frequently Asked Questions

What is the CAS number of Pazopanib?

The CAS registry number of Pazopanib is 444731-52-6.

What is the molecular formula and molecular weight of Pazopanib?

Molecular formula C21H23N7O2S, molecular weight 437.5.

What other names is Pazopanib known by?

It is also registered under: Pazopanib, 帕唑帕尼.

What are the documented applications of Pazopanib?

Recorded applications: MEDICATION, THERAPEUTIC CATEGORY: Antineoplastic, Methods of Manufacturing: Preparation: A. Boloor et al, World Intellectual Property Organization patent 02059110 (2002 to Glaxo), eidem, United States of America patent 7105530 (2006 to SKB).

Which category does Pazopanib belong to?

Category: Organic Chemicals.

Packaging & documentation

Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.

PubChem Public Data

Independent reference data for Pazopanib (CAS 444731-52-6), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number444731-52-6
PubChem CID10113978
Molecular formulaC21H23N7O2S
IUPAC name5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide
UNII (FDA)7RN5DR86CK

Computed descriptors

Molecular Weight437.5
XLogP33.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Exact Mass437.16339418
Monoisotopic Mass437.16339418
Topological Polar Surface Area127
Heavy Atom Count31

Physicochemical values on record

LogP3.3

Documented uses on record

    THERAPEUTIC CATEGORY: AntineoplasticPreparation: A. Boloor et al., World Intellectual Property Organization patent 02059110 (2002 to Glaxo); eidem, United States of America patent 7105530 (2006 to SKB).

    Synonyms and trade names

    Pazopanib; 444731-52-6; GW786034; 5-((4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide; pazopanibum; DTXSID8048733; 7RN5DR86CK; NSC-752782; GW780604; GW-780604; 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide; DTXCID1028659; CHEBI:71219; Benzenesulfonamide, 5-((4-((2,3-dimethyl-2H-indazol-6-yl)methylamino)-2-pyrimidinyl)amino)-2-methyl-; 5-({4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzenesulfonamide; Benzenesulfonamide, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-

    GHS hazard classification

    Reported hazard statementsH302 (50%), H315 (50%), H319 (50%), H335 (50%), H361 (25%), H373 (25%), H411 (25%)

    H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]

    H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]

    What the public record says

    Pazopanib · CAS 444731-52-6 · C21H23N7O2S. UNII 7RN5DR86CK. LogP: 3.3.

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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