N-{[(2R)-2,3-二羟基丙基]氧基}-3,4-二氟-2-[(2-氟-4-碘苯基)氨基]苯甲酰胺

Name: N-{[(2R)-2,3-二羟基丙基]氧基}-3,4-二氟-2-[(2-氟-4-碘苯基)氨基]苯甲酰胺
Brand: 济南圣和化工有限公司

CAS 391209-97-5C16H14F3IN2O4MW 482.19

济南圣和化工有限公司现供应有机化学品——N-{[(2R)-2,3-二羟基丙基]氧基}-3,4-二氟-2-[(2-氟-4-碘苯基)氨基]苯甲酰胺（CAS 391209-97-5），分子式 C16H14F3IN2O4，分子量 482.19。本页理化参数仅供参考，实际常规纯度按批次COA提供(不公开发布)，以批次 COA 及订单确认为准，支持批量采购与长期供货协议。

产品概览

CAS号	391209-97-5
分子式	C16H14F3IN2O4
分子量	482.19
LogP	3
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	有机化学品
类别	有机化学品

应用领域

有机化学品

N-{[(2R)-2,3-二羟基丙基]氧基}-3,4-二氟-2-[(2-氟-4-碘苯基)氨基]苯甲酰胺在有机化学品领域使用广泛。采购前请确认纯度等级与包装形式，以批次 COA 为验收依据。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

采购提示：本产品按按订单/批次确认(不公开发布)起订发货，收到货物后请先核对包装完好性再行入库。储存条件为阴凉干燥、密封保存；如需 MSDS 或运输说明，可在询价时一并索取。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

作为化工原料供应服务商，济南圣和化工有限公司长期服务于化工贸易、食品添加、医药中间体、日化原料等行业的采购需求。除 N-{[(2R)-2,3-二羟基丙基]氧基}-3,4-二氟-2-[(2-氟-4-碘苯基)氨基]苯甲酰胺外，您还可以在站内按 CAS 号或产品分类检索更多品类，获取规格与报价。

常见问题

N-{[(2R)-2,3-二羟基丙基]氧基}-3,4-二氟-2-[(2-氟-4-碘苯基)氨基]苯甲酰胺的 CAS 号是多少？

N-{[(2R)-2,3-二羟基丙基]氧基}-3,4-二氟-2-[(2-氟-4-碘苯基)氨基]苯甲酰胺的 CAS 号为 391209-97-5。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

N-{[(2R)-2,3-二羟基丙基]氧基}-3,4-二氟-2-[(2-氟-4-碘苯基)氨基]苯甲酰胺有什么用途？

主要应用于有机化学品。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide · CAS 391209-97-5 · C16H14F3IN2O4. UNII 86K0J5AK6M. Dissociation Constants: 7.96.

Identification

CAS Registry Number	391209-97-5
PubChem CID	9826528
Molecular formula	C16H14F3IN2O4
IUPAC name	N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzamide
UNII (FDA)	86K0J5AK6M

Computed Descriptors

Molecular Weight	482.19
XLogP3	3
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	7
Exact Mass	481.99504
Monoisotopic Mass	481.99504
Topological Polar Surface Area	90.8
Heavy Atom Count	26
Formal Charge	0

Physical & Chemical Properties

Dissociation Constants	7.96

Physical description & handling notes

In a mouse model of NF1, oral dosing of mirdametinib inhibited ERK phosphorylation and reduced neurofibroma tumour volume and proliferation.

GHS Hazard Classification

Reported hazard statements	H301 (97.5%), H373 (97.5%), H400 (95%), H410 (97.5%)

H301 (97.5%): Toxic if swallowed [Danger Acute toxicity, oral]

H373 (97.5%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

Documented Uses

Mirdametinib is indicated for the treatment of neurofibromatosis type 1 (NF1) in patients two years and older with symptomatic plexiform neurofibromas (PN) that are not amenable to complete resection.
Breast Feeding; Lactation; Milk, Human; Antineoplastic Agents; Enzyme Inhibitors; Protein Kinase Inhibitors; MEK inhibitors
Take with or without food. Food has no clinically significant effects on drug exposure.
Agents that inhibit PROTEIN KINASES.
Established Pharmacologic Class [EPC] - Kinase Inhibitor
Mechanisms of Action [MoA] - Mitogen-Activated Protein Kinase Kinase 1 Inhibitors

Synonyms

391210-10-9; Mirdametinib; PD0325901; PD 0325901; PD-0325901; N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide; GOMEKLI; PD 325901; 86K0J5AK6M; DTXSID0044024; DTXCID8024024; CHEBI:88249; Pd 901; PD-901; Benzamide, N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-; PD-03525901

Frequently Asked Questions

What are the CAS number and molecular formula of N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide?

CAS 391209-97-5; molecular formula C16H14F3IN2O4; molecular weight — g/mol.

What other names is N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide known by?

391210-10-9, Mirdametinib, PD0325901, PD 0325901, PD-0325901, N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide.

Is N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide classified as hazardous?

Hazard statements reported: H301, H373, H400, H410.

What are the key physical properties of N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide?

Dissociation Constants: 7.96.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.