N-3,4-二甲基异恶唑-5-基-N-磺酰基乙酰胺

Name: N-3,4-二甲基异恶唑-5-基-N-磺酰基乙酰胺
Brand: 济南圣和化工有限公司

CAS 80-74-0C13H15N3O4SMW 309.34

济南圣和化工有限公司现供应有机化学品——N-3,4-二甲基异恶唑-5-基-N-磺酰基乙酰胺（CAS 80-74-0），分子式 C13H15N3O4S，分子量 309.34。本页理化参数仅供参考，实际常规纯度按批次COA提供(不公开发布)，以批次 COA 及订单确认为准，支持批量采购与长期供货协议。

产品概览

CAS号	80-74-0
分子式	C13H15N3O4S
分子量	309.34
熔点	192
LogP	1.3
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	有机化学品
类别	有机化学品

应用领域

有机化学品

N-3,4-二甲基异恶唑-5-基-N-磺酰基乙酰胺在有机化学品领域使用广泛。采购前请确认纯度等级与包装形式，以批次 COA 为验收依据。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

采购提示：本产品按按订单/批次确认(不公开发布)起订发货，收到货物后请先核对包装完好性再行入库。储存条件为阴凉干燥、密封保存；如需 MSDS 或运输说明，可在询价时一并索取。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

选择济南圣和化工有限公司的理由：产品信息透明（含 CAS、分子式、理化参数）、报价响应快（一个工作日内）、单证齐全（COA/MSS/质检资料按需提供）、支持批量与长期协议供货。如需 N-3,4-二甲基异恶唑-5-基-N-磺酰基乙酰胺以外的配套原料，也欢迎一并列出需求清单。

常见问题

N-3,4-二甲基异恶唑-5-基-N-磺酰基乙酰胺的 CAS 号是多少？

N-3,4-二甲基异恶唑-5-基-N-磺酰基乙酰胺的 CAS 号为 80-74-0。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

N-3,4-二甲基异恶唑-5-基-N-磺酰基乙酰胺有什么用途？

主要应用于有机化学品。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

N-3,4-dimethylisoxazol-5-yl-N-sulfanilylacetamide · CAS 80-74-0 · C13H15N3O4S. UNII WBT5QH3KED. Melting Point: 192.

Identification

CAS Registry Number	80-74-0
PubChem CID	6662
Molecular formula	C13H15N3O4S
IUPAC name	N-(4-aminophenyl)sulfonyl-N-(3,4-dimethyl-1,2-oxazol-5-yl)acetamide
UNII (FDA)	WBT5QH3KED

Computed Descriptors

Molecular Weight	309.34
XLogP3	1.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Exact Mass	309.07832714
Monoisotopic Mass	309.07832714
Topological Polar Surface Area	115
Heavy Atom Count	21
Formal Charge	0

Physical & Chemical Properties

Melting Point	192

Physical description & handling notes

161.2 Å² [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Documented Uses

Readily absorbed from the gastrointestinal tract. In a pharmacokinetic study, the adjustments for variable renal clearances between oral and intravenous administration and using the unbound plasma concentrations, the bioavailability for an oral dose of sulfisoxazole was found to be 0.95 +/- 0.04.
The mean urinary excretion recovery following oral administration of sulfisoxazole is 97% within 48 hours, of which 52% is the parent drug, and the remaining as the N4-acetylated metabolite. It is excreted in human milk. Sulfisoxazole and its acetylated metabolites are excreted primarily by the kidneys through glomerular filtration.
The sulfonamides are widely distributed throughout all body tissues. It readily crosses the placental barrier and enters into fetal circulation and also crosses the blood-brain barrier. In healthy subjects, cerebrospinal fluid concentrations of sulfisoxazole vary; in patients with meningitis, however, concentrations of free drug in cerebrospinal fluid as high as 94 mcg/mL have been reported. In a pharmacokinetic study, the apparent volume of distribution for total drug was 10.9 +/- 2.0 liters and 136 +/- 36 liters
The clearance of sulfisoxazole is 18.7 +/- 3.9 ml/min for total drug and 232 +/- 64 ml/min for the unbound drug.
Approximately 85% of a dose of sulfisoxazole is bound to plasma proteins, primarily to albumin; 65% to 72% of the unbound portion is in the nonacetylated form.
The serum half-life is 10 -12 hours.

Synonyms

Sulfisoxazole acetyl; 80-74-0; ACETYL SULFISOXAZOLE; Lipo Gantrisin; acetylsulfafurazole; Acetylsulfisoxazole; GANTRISIN PEDIATRIC; Acetyl sulfafurazole; Sulfafurazole acetyl; Sulfisoxizole acetyl; WBT5QH3KED; NSC-759138; Sulfisoxazole acetyl (USP); Sulfisoxazole acetyl [USP]; N-3,4-Dimethylisoxazol-5-yl-N-sulphanilylacetamide; Acetamide, N-((4-aminophenyl)sulfonyl)-N-(3,4-dimethyl-5-isoxazolyl)-

Frequently Asked Questions

What are the CAS number and molecular formula of N-3,4-dimethylisoxazol-5-yl-N-sulfanilylacetamide?

CAS 80-74-0; molecular formula C13H15N3O4S; molecular weight — g/mol.

What other names is N-3,4-dimethylisoxazol-5-yl-N-sulfanilylacetamide known by?

Sulfisoxazole acetyl, 80-74-0, ACETYL SULFISOXAZOLE, Lipo Gantrisin, acetylsulfafurazole, Acetylsulfisoxazole.

What are the key physical properties of N-3,4-dimethylisoxazol-5-yl-N-sulfanilylacetamide?

Melting Point: 192.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.