N-磺胺基乙酰胺

Description

Sulphacetamide · CAS 144-80-9 · C8H10N2O3S. UNII 4965G3J0F5. Melting Point: 360 to 363 °F (NTP, 1992); Melting Point: 183; Melting Point: 183 °C.

Identification

CAS Registry Number	144-80-9
PubChem CID	5320
Molecular formula	C8H10N2O3S
IUPAC name	N-(4-aminophenyl)sulfonylacetamide
UNII (FDA)	4965G3J0F5

Computed Descriptors

Molecular Weight	214.24
XLogP3	-1
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	214.04121336
Monoisotopic Mass	214.04121336
Topological Polar Surface Area	97.6
Heavy Atom Count	14
Formal Charge	0

Physical & Chemical Properties

Melting Point	360 to 363 °F (NTP, 1992)
Melting Point	183
Melting Point	183 °C
Solubility	12500
Solubility	4.21e+00 g/L
LogP	-0.96
LogP	-0.6
LogP	-0.1
Collision Cross Section	141.21 Ų [M+H]+
Collision Cross Section	152.76 Ų [M+Na]+

Physical description & handling notes

• Sulfacetamide is a white powder. (NTP, 1992)
• Solid
• less than 0.1 mg/mL at 61 °F (NTP, 1992)
• >32.1 [ug/mL] (The mean of the results at pH 7.4)
• 154.8 Ų [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID8026060]
• 146.7 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID8026060]

Regulatory Status

GHS notification summary	10% (4 / 40)

GHS Hazard Classification

GHS notification summary	10% (4 / 40)
Reported hazard statements	H317 (77.5%), H335 (77.5%), H341 (12.5%)

Documented Uses

• Pharmaceuticals -> Animal Drugs -> Approved in Taiwan
• Acetamide, N-[(4-aminophenyl)sulfonyl]-: ACTIVE
• For the treatment of bacterial vaginitis, keratitis, acute conjunctivitis, and blepharitis.
• Sulfacetamide (Class: Other Substances, Added Date: 02-2003)
• Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.
• Substances capable of killing agents causing urinary tract infections or of preventing them from spreading.

Synonyms

sulfacetamide; 144-80-9; Sulphacetamide; Acetosulfamine; N-((4-Aminophenyl)sulfonyl)acetamide; N-Acetylsulfanilamide; Urosulfon; N-Sulfanilylacetamide; Acetosulfamin; Acetocid; Sulfacet; N-(4-aminophenyl)sulfonylacetamide; N-Sulphanilylacetamide; Formosulfacetamide; Sulfacetimide; Albamine

Frequently Asked Questions

What are the CAS number and molecular formula of Sulphacetamide?

CAS 144-80-9; molecular formula C8H10N2O3S; molecular weight — g/mol.

What other names is Sulphacetamide known by?

sulfacetamide, 144-80-9, Sulphacetamide, Acetosulfamine, N-((4-Aminophenyl)sulfonyl)acetamide, N-Acetylsulfanilamide.

Is Sulphacetamide classified as hazardous?

10% of GHS notifications report no hazard classification (4 of 40).

What are the key physical properties of Sulphacetamide?

Melting Point: 360 to 363 °F (NTP, 1992); Melting Point: 183; Melting Point: 183 °C; Solubility: 12500.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.