奈必洛尔

Name: 奈必洛尔
Brand: 济南圣和化工有限公司

CAS 99200-09-6C22H25F2NO4MW 405.4

济南圣和化工主营供应奈必洛尔（CAS 99200-09-6），归类于有机化学品，分子式 C22H25F2NO4，分子量 405.4。我们面向国内化工贸易与生产企业提供稳定的现货供应，报价响应快，支持对公转账并可开具增值税发票。

产品概览

CAS号	99200-09-6
分子式	C22H25F2NO4
分子量	405.4
熔点	223.0-228.0
LogP	4.183
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	有机化学品
类别	有机化学品

应用领域

有机化学品

奈必洛尔主要应用于有机化学品。具体使用工况下的添加量与规格要求，欢迎与技术团队沟通确认。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

供应说明：奈必洛尔常规包装为按订单/批次确认(不公开发布)，储存时应密封置于阴凉干燥处，避免与氧化剂混放。济南圣和化工有限公司支持国内物流发货，大货交期与运费以订单确认为准。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

选择济南圣和化工有限公司的理由：产品信息透明（含 CAS、分子式、理化参数）、报价响应快（一个工作日内）、单证齐全（COA/MSS/质检资料按需提供）、支持批量与长期协议供货。如需奈必洛尔以外的配套原料，也欢迎一并列出需求清单。

常见问题

奈必洛尔的 CAS 号是多少？

奈必洛尔的 CAS 号为 99200-09-6。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

奈必洛尔有什么用途？

主要应用于有机化学品。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

Nebivolol · CAS 99200-09-6 · C22H25F2NO4. UNII 030Y90569U. Melting Point: 223.0-228.0; Solubility: 0.091g/100mL; Solubility: 4.03e-02 g/L.

Identification

CAS Registry Number	99200-09-6
PubChem CID	71301
Molecular formula	C22H25F2NO4
IUPAC name	1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]ethanol
UNII (FDA)	030Y90569U

Computed Descriptors

Molecular Weight	405.4
XLogP3	3
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	6
Exact Mass	405.17516460
Monoisotopic Mass	405.17516460
Topological Polar Surface Area	71
Heavy Atom Count	29
Formal Charge	0

Physical & Chemical Properties

Melting Point	223.0-228.0
Solubility	0.091g/100mL
Solubility	4.03e-02 g/L
LogP	4.183
LogP	2.76
Dissociation Constants	8.22
Dissociation Constants	8.13

Physical description & handling notes

Solid

GHS Hazard Classification

Reported hazard statements	H302 (100%), H315 (50%), H319 (50%), H332 (50%), H335 (50%), H361 (50%)

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]

Documented Uses

Use (kg; approx.) in Germany (2009): >750
Consumption (g per capita; approx.) in Germany (2009): 0.00916
Nebivolol is indicated to treat hypertension.
Nebivolol is an FDA-approved medication used to treat hypertension. Beta-blockers are a class of agents used to treat multiple conditions, including hypertension, angina, arrhythmias, anxiety, hyperthyroidism, migraine prevention, and prevention of essential tremors. The American College of Cardiology (ACC)/American Heart Association (AHA) guidelines advise against using β-blockers as the first-line treatment for hypertension and to reserve them for patients with comorbidities such as ischemic heart disease.
Nebivolol is a beta-blocker and antihypertensive medication that has additional vasodilatory activity mediated by nitric oxide release. Nebivolol has yet to be linked to instances of clinically apparent liver injury.
Breast Feeding; Lactation; Milk, Human; Adrenergic beta-Antagonists; Antihypertensive Agents; Vasodilator Agents

Synonyms

Nebivolol; Narbivolol; 118457-14-0; R-65824; dl-Nebivolol; DTXSID9040556; R65,824; Nebivololum; nebibolol; Hypoloc; Hydrochloride, Nebivolol; RefChem:56585; alpha,alpha'-(iminobis(methylene))bis(6-fluoro-3,4-dihydro)-2H-1-benzopyran-2-methanol; DTXCID7020556; CHEBI:64022; C07AB12

Frequently Asked Questions

What are the CAS number and molecular formula of Nebivolol?

CAS 99200-09-6; molecular formula C22H25F2NO4; molecular weight — g/mol.

What other names is Nebivolol known by?

Nebivolol, Narbivolol, 118457-14-0, R-65824, dl-Nebivolol, DTXSID9040556.

Is Nebivolol classified as hazardous?

Hazard statements reported: H302, H315, H319, H332, H335.

What are the key physical properties of Nebivolol?

Melting Point: 223.0-228.0; Solubility: 0.091g/100mL; Solubility: 4.03e-02 g/L; LogP: 4.183.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.