溴化甲基纳曲酮

Description

Methylnaltrexone Bromide · CAS 73232-52-7 · C21H26BrNO4. UNII RFO6IL3D3M.

Identification

CAS Registry Number	73232-52-7
PubChem CID	5361917
Molecular formula	C21H26BrNO4
IUPAC name	(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7-one bromide
UNII (FDA)	RFO6IL3D3M

Computed Descriptors

Molecular Weight	436.3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	435.10452
Monoisotopic Mass	435.10452
Topological Polar Surface Area	66.8
Heavy Atom Count	27
Formal Charge	0
Complexity	664

GHS Hazard Classification

Reported hazard statements	H301 (66.7%), H302 (31.6%), H312 (29.8%), H317 (29.8%), H332 (29.8%), H334 (29.8%), H400 (66.7%)

Documented Uses

• Breast Feeding; Lactation; Milk, Human; Narcotic Antagonists
• Methylnaltrexone bromide is approved to treat:
• • Constipation caused by the use of opioids. It is used in adults with pain caused by cancer or treatment for cancer or by other advanced disease.
• Agents inhibiting the effect of narcotics on the central nervous system.
• Opioid Antagonists [MoA]; Quaternary Ammonium Compounds [CS]; Opioid Antagonist [EPC]
• A - Alimentary tract and metabolism

Synonyms

Methylnaltrexone bromide; Relistor; Naltrexone methobromide; N-Methylnaltrexone Bromide; MRZ-2663BR; MOA-728; bromuro de metilnaltrexona; bromure de methylnaltrexone; MRZ2663BR; MOA728; DTXSID30868236; NALTREXONE METHYLBROMIDE; methylnaltrexoni bromidum; RefChem:56830; A06AH01; DTXCID40820845

Frequently Asked Questions

What are the CAS number and molecular formula of Methylnaltrexone Bromide?

CAS 73232-52-7; molecular formula C21H26BrNO4; molecular weight — g/mol.

What other names is Methylnaltrexone Bromide known by?

Methylnaltrexone bromide, Relistor, Naltrexone methobromide, N-Methylnaltrexone Bromide, MRZ-2663BR, MOA-728.

Is Methylnaltrexone Bromide classified as hazardous?

Hazard statements reported: H301, H302, H312, H317, H332.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.