methylergometrine (CAS 113-42-8) — formula C20H25N3O2, molecular weight 339.4; category organic chemicals.
methylergometrine (CAS 113-42-8) is a chemical raw material in the organic chemicals category. Its molecular formula C20H25N3O2 comprises 20 C, 25 H, 3 N, 2 O atoms. Its molecular weight is about 339.4. Reported physicochemical data: melting point around 172, LogP about 1.2. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 113-42-8 |
|---|---|
| Molecular Formula | C20H25N3O2 |
| Molecular Weight | 339.4 |
| Melting Point | 172 |
| LogP | 1.2 |
| Applications | MEDICATION, Methylergometrine is a synthetic analogue of ergonovine, an alkaloid of the ergoline family that occurs in various species of vines of the Convolvulaceae (morning glory) family and in some species of lower fungi like other ergoline alkaloids. Methylergometrine is a blood vessel constrictor and smooth muscle agonist most commonly used to prevent or control excessive bleeding following childbirth and spontaneous or elective abortion. It also causes uterine contractions to aid in expulsion of retained products of conception after a missed abortion (miscarriage in which all or part of the fetus remains in the uterus) and to help deliver the placenta after childbirth. The drug is currently prepared via reaction of (+)-lysergic acid with L-(+)-aminobutanol, using different coupling reagents, and is available under the name Methergine as tablets or injection (IM or IV) or in liquid form to be taken orally. (L1918, L1923) |
| Category | Organic Chemicals |
Documented applications: MEDICATION, Methylergometrine is a synthetic analogue of ergonovine, an alkaloid of the ergoline family that occurs in various species of vines of the Convolvulaceae (morning glory) family and in some species of lower fungi like other ergoline alkaloids. Methylergometrine is a blood vessel constrictor and smooth muscle agonist most commonly used to prevent or control excessive bleeding following childbirth and spontaneous or elective abortion. It also causes uterine contractions to aid in expulsion of retained products of conception after a missed abortion (miscarriage in which all or part of the fetus remains in the uterus) and to help deliver the placenta after childbirth. The drug is currently prepared via reaction of (+)-lysergic acid with L-(+)-aminobutanol, using different coupling reagents, and is available under the name Methergine as tablets or injection (IM or IV) or in liquid form to be taken orally. (L1918, L1923).
methylergometrine is a carbon-based organic compound with CAS registry number 113-42-8 and molecular formula C20H25N3O2 (molecular weight 339.4), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 113-42-8
Its molecular formula C20H25N3O2 comprises 20 C, 25 H, 3 N, 2 O atoms.
Also known as: methylergometrine · 甲基麦角新碱
Category: organic chemicals
The CAS registry number of methylergometrine is 113-42-8.
Molecular formula C20H25N3O2, molecular weight 339.4.
It is also registered under: methylergometrine, 甲基麦角新碱.
Recorded applications: MEDICATION, Methylergometrine is a synthetic analogue of ergonovine, an alkaloid of the ergoline family that occurs in various species of vines of the Convolvulaceae (morning glory) family and in some species of lower fungi like other ergoline alkaloids. Methylergometrine is a blood vessel constrictor and smooth muscle agonist most commonly used to prevent or control excessive bleeding following childbirth and spontaneous or elective abortion. It also causes uterine contractions to aid in expulsion of retained products of conception after a missed abortion (miscarriage in which all or part of the fetus remains in the uterus) and to help deliver the placenta after childbirth. The drug is currently prepared via reaction of (+)-lysergic acid with L-(+)-aminobutanol, using different coupling reagents, and is available under the name Methergine as tablets or injection (IM or IV) or in liquid form to be taken orally. (L1918, L1923).
Category: Organic Chemicals.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for methylergometrine (CAS 113-42-8), compiled from public chemistry databases.
| CAS Registry Number | 113-42-8 |
|---|---|
| PubChem CID | 8226 |
| Molecular formula | C20H25N3O2 |
| IUPAC name | (6aR,9R)-N-[(2S)-1-hydroxybutan-2-yl]-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide |
| UNII (FDA) | W53L6FE61V |
| Molecular Weight | 339.4 |
|---|---|
| XLogP3 | 2.3 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 4 |
| Exact Mass | 339.19467705 |
| Monoisotopic Mass | 339.19467705 |
| Topological Polar Surface Area | 68.4 |
| Heavy Atom Count | 25 |
| Melting Point | 172 |
|---|---|
| Melting Point | 172 °C |
| Solubility | 25 |
| Solubility | 2.04e-01 g/L |
| LogP | 1.2 |
methylergonovine; Methylergometrine; Methylergobasin; Methylergobasine; Methylergobrevin; Methylergometrin; Methylergonovin; 113-42-8; Partergin; Basofortina; Ergotyl; Metilergometrina; Methergin; Methylergometrinum; Ergometrine, methyl-; D-Lysergic acid-(+)-butanolamide-(2)
methylergometrine · CAS 113-42-8 · C20H25N3O2. UNII W53L6FE61V. Melting Point: 172; Melting Point: 172 °C; Solubility: 25.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 甲基麦角新碱