盐酸咪达唑仑

Description

Midazolam HCL · CAS 59467-96-8 · C18H14Cl2FN3. UNII W7TTW573JJ.

Identification

CAS Registry Number	59467-96-8
PubChem CID	43032
Molecular formula	C18H14Cl2FN3
IUPAC name	8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine;hydrochloride
UNII (FDA)	W7TTW573JJ

Computed Descriptors

Molecular Weight	362.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Exact Mass	361.0548810
Monoisotopic Mass	361.0548810
Topological Polar Surface Area	30.2
Heavy Atom Count	24
Formal Charge	0
Complexity	471

GHS Hazard Classification

Reported hazard statements	H302 (100%), H336 (100%), H361 (100%), H362 (100%)

Documented Uses

• Intravenous midazolam is indicated for procedural sedation (often in combination with an opioid, such as fentanyl), for pre-op sedation, for the induction of general anesthesia, and for sedation of ventilated patients in critical care units. Oral midazolam is indicated for the short term treatment of moderately severe insomnia in patients who did not adequately react to other hypnotics, and who have persistent trouble in falling asleep. [Wikipedia]
• Agents that are administered in association with anesthetics to increase effectiveness, improve delivery, or decrease required dosage.
• Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
• Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here.
• Ultrashort-acting anesthetics that are used for induction. Loss of consciousness is rapid and induction is pleasant, but there is no muscle relaxation and reflexes frequently are not reduced adequately. Repeated administration results in accumulation and prolongs the recovery time. Since these agents have little if any analgesic activity, they are seldom used alone except in brief minor procedures. (From AMA Drug Evaluations Annual, 1994, p174)
• Benzodiazepine [EPC]; Benzodiazepines [CS]

Synonyms

MIDAZOLAM HYDROCHLORIDE; Midazolam Hcl; 59467-96-8; Hypnovel; Rocam; Ro 21-3981/003; DTXSID8047846; Midazolam hydrochloride civ; W7TTW573JJ; NSC-751451; SEIZALAM; SHP615; SHP-615; Midazolam hydrochloride preservative free; Ro-213981001; CHEBI:6932

Frequently Asked Questions

What are the CAS number and molecular formula of Midazolam HCL?

CAS 59467-96-8; molecular formula C18H14Cl2FN3; molecular weight — g/mol.

What other names is Midazolam HCL known by?

MIDAZOLAM HYDROCHLORIDE, Midazolam Hcl, 59467-96-8, Hypnovel, Rocam, Ro 21-3981/003.

Is Midazolam HCL classified as hazardous?

Hazard statements reported: H302, H336, H361, H362.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.