甲基泼尼松龙半琥珀酸盐

Description

Methylprednisolone Hemisuccinate · CAS 2921-57-5 · C26H34O8. UNII 5GMR90S4KN.

Identification

CAS Registry Number	2921-57-5
PubChem CID	16923
Molecular formula	C26H34O8
IUPAC name	4-[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid
UNII (FDA)	5GMR90S4KN

Computed Descriptors

Molecular Weight	474.5
XLogP3	2.2
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	7
Exact Mass	474.22536804
Monoisotopic Mass	474.22536804
Topological Polar Surface Area	138
Heavy Atom Count	34
Formal Charge	0

Physical description & handling notes

• Methylprednisolone sodium succinate (the sodium salt of methylprednisolone hemisuccinate) has the same metabolic and anti-inflammatory actions as methylprednisolone. When given parenterally and in equimolar quantities, the two compounds are equivalent in biologic activity.

GHS Hazard Classification

Reported hazard statements	H302 (30.4%), H312 (30.4%), H360 (62.5%), H361 (33.9%), H373 (66.1%)

Documented Uses

• Substances that reduce or suppress INFLAMMATION.
• A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
• Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.

Synonyms

2921-57-5; METHYLPREDNISOLONE HEMISUCCINATE; Methylprednisolone succinate; 5GMR90S4KN; Methylprednisolone Hemisuccinate [USP]; Methylprednisolone hemisuccinate (USP); 6 alpha-Methylprednisolone Sodium Hemisuccinate; UrbasonSoluble; RefChem:389122; Succinate, Methylprednisolone; Hemisuccinate, Methylprednisolone; Sodium Succinate, Methylprednisolone; Sodium Hemisuccinate, Methylprednisolone; Methylprednisolone Hemisuccinate Monosodium Salt; 220-863-9; Methylprednisolone hydrogen succinate

Frequently Asked Questions

What are the CAS number and molecular formula of Methylprednisolone Hemisuccinate?

CAS 2921-57-5; molecular formula C26H34O8; molecular weight — g/mol.

What other names is Methylprednisolone Hemisuccinate known by?

2921-57-5, METHYLPREDNISOLONE HEMISUCCINATE, Methylprednisolone succinate, 5GMR90S4KN, Methylprednisolone Hemisuccinate [USP], Methylprednisolone hemisuccinate (USP).

Is Methylprednisolone Hemisuccinate classified as hazardous?

Hazard statements reported: H302, H312, H360, H361, H373.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.