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Mitoxantrone hydrochloride

CAS 70476-82-3C22H30Cl2N4O6MW 517.4

Mitoxantrone hydrochloride (CAS 70476-82-3) — formula C22H30Cl2N4O6, molecular weight 517.4; category organic chemicals.

Product Description

Mitoxantrone hydrochloride (CAS 70476-82-3) is a chemical raw material in the organic chemicals category. Its molecular formula C22H30Cl2N4O6 comprises 22 C, 30 H, 2 Cl, 4 N, 6 O atoms. Its molecular weight is about 517.4. Reported physicochemical data: melting point around 203-5 °C. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.

Product Overview

CAS Number70476-82-3
Molecular FormulaC22H30Cl2N4O6
Molecular Weight517.4
Melting Point203-5 °C
Applicationsantineoplastic drug, DNA binding or cleaving agent used to treat acute nonlymphocytic leukemia, including myclogenous, promyclocytic, monocytic, and erythroid acute leukemias
CategoryOrganic Chemicals

Applications

Documented applications: antineoplastic drug, DNA binding or cleaving agent used to treat acute nonlymphocytic leukemia, including myclogenous, promyclocytic, monocytic, and erythroid acute leukemias.

Technical Profile

What this product is

Mitoxantrone hydrochloride is a carbon-based organic compound with CAS registry number 70476-82-3 and molecular formula C22H30Cl2N4O6 (molecular weight 517.4), belonging to the organic chemicals segment of chemical raw materials.

Identification

CAS number: 70476-82-3

Its molecular formula C22H30Cl2N4O6 comprises 22 C, 30 H, 2 Cl, 4 N, 6 O atoms.

Also known as: Mitoxantrone hydrochloride · 盐酸米托蒽醌

Category: organic chemicals

Frequently Asked Questions

What is the CAS number of Mitoxantrone hydrochloride?

The CAS registry number of Mitoxantrone hydrochloride is 70476-82-3.

What is the molecular formula and molecular weight of Mitoxantrone hydrochloride?

Molecular formula C22H30Cl2N4O6, molecular weight 517.4.

What other names is Mitoxantrone hydrochloride known by?

It is also registered under: Mitoxantrone hydrochloride, 盐酸米托蒽醌.

What are the documented applications of Mitoxantrone hydrochloride?

Recorded applications: antineoplastic drug, DNA binding or cleaving agent used to treat acute nonlymphocytic leukemia, including myclogenous, promyclocytic, monocytic, and erythroid acute leukemias.

Which category does Mitoxantrone hydrochloride belong to?

Category: Organic Chemicals.

Packaging & documentation

Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.

PubChem Public Data

Independent reference data for Mitoxantrone hydrochloride (CAS 70476-82-3), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number70476-82-3
PubChem CID51082
Molecular formulaC22H30Cl2N4O6
IUPAC name1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione;dihydrochloride
UNII (FDA)U6USW86RD0

Computed descriptors

Molecular Weight517.4
Hydrogen Bond Donor Count10
Hydrogen Bond Acceptor Count10
Rotatable Bond Count12
Exact Mass516.1542401
Monoisotopic Mass516.1542401
Topological Polar Surface Area163
Heavy Atom Count34

Physicochemical values on record

Melting Point203-5 °C
SolubilityH2O 5- 10 (mg/mL)
Solubility0.1NHCl 1 - 3 (mg/mL)
Solubility10% Ethanol 3 - 5 (mg/mL)
Solubility95% Ethanol < 1 (mg/mL)
SolubilityMethanol < 1 (mg/mL)

Documented uses on record

    Used as an antineoplastic drug; [Merck Index]DNA binding or cleaving agent used to treat acute nonlymphocytic leukemia, including myclogenous, promyclocytic, monocytic, and erythroid acute leukemias

    Synonyms and trade names

    70476-82-3; Mitoxantrone hydrochloride; Mitoxantrone dihydrochloride; CL-232315; Onkotrone; DTXSID0045173; Mitozantrone hydrochloride; CL 232,315; U6USW86RD0; NSC-301739; CL 232315; DTXCID8025173; CHEBI:50727; 1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthraquinone dihydrochloride; 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)-, dihydrochloride; 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinone dihydrochloride

    GHS hazard classification

    Reported hazard statementsH340 (92.9%), H360 (92.9%), H302, H310, H341, H351, H370, H372

    H340 (92.9%): May cause genetic defects [Danger Germ cell mutagenicity]

    H360 (92.9%): May damage fertility or the unborn child [Danger Reproductive toxicity]

    What the public record says

    Mitoxantrone hydrochloride · CAS 70476-82-3 · C22H30Cl2N4O6. UNII U6USW86RD0. Melting Point: 203-5 °C; Solubility: H2O 5- 10 (mg/mL); Solubility: 0.1NHCl 1 - 3 (mg/mL).

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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