洛本扎里特

Description

Lobenzarit · CAS 63329-53-3 · C14H10ClNO4. UNII 915EE91P39.

Identification

CAS Registry Number	63329-53-3
PubChem CID	3946
Molecular formula	C14H10ClNO4
IUPAC name	2-(2-carboxyanilino)-4-chlorobenzoic acid
UNII (FDA)	915EE91P39

Computed Descriptors

Molecular Weight	291.68
XLogP3	5.1
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	4
Exact Mass	291.0298355
Monoisotopic Mass	291.0298355
Topological Polar Surface Area	86.6
Heavy Atom Count	20
Formal Charge	0

Documented Uses

• Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune
• Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
• Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.

Synonyms

Lobenzarit; 63329-53-3; Lobenzaritum; 2-((2-carboxyphenyl)amino)-4-chlorobenzoic acid; 2-[(2-carboxyphenyl)amino]-4-chlorobenzoic acid; 915EE91P39; Benzoic acid, 2-((2-carboxyphenyl)amino)-4-chloro-; DTXSID20212709; lobenzart; CCA lobenzarit; 4-chloro-2,2'-iminodibenzoic acid; lobenzarit, disodium salt; N-(2-carboxyphenyl)-4-chloroanthranilic acid; RefChem:153876; DTXCID00135200; 2-(2-carboxyanilino)-4-chlorobenzoic acid

Frequently Asked Questions

What are the CAS number and molecular formula of Lobenzarit?

CAS 63329-53-3; molecular formula C14H10ClNO4; molecular weight — g/mol.

What other names is Lobenzarit known by?

Lobenzarit, 63329-53-3, Lobenzaritum, 2-((2-carboxyphenyl)amino)-4-chlorobenzoic acid, 2-[(2-carboxyphenyl)amino]-4-chlorobenzoic acid, 915EE91P39.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.