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雷迪帕韦

CAS 1256388-51-8C49H54F2N8O6MW 889.0

雷迪帕韦(CAS 1256388-51-8)属有机化学品类产品,分子式 C49H54F2N8O6,分子量 889.0。济南圣和化工有限公司常年现货供应该产品,常规纯度 按批次COA提供(不公开发布),可按客户需求安排分装包装,欢迎邮件或来电询价。

产品概览

CAS号1256388-51-8
分子式C49H54F2N8O6
分子量889.0
LogP3.8
纯度按批次COA提供(不公开发布)
包装按订单/批次确认(不公开发布)
应用领域有机化学品
类别有机化学品

应用领域

有机化学品

该产品的下游应用集中在有机化学品。不同客户工艺差异较大,我们支持按需提供样品与小批量试用。

包装与储存

包装规格按订单/批次确认(不公开发布)
纯度规格按批次COA提供(不公开发布)
储存条件密封、阴凉干燥处保存
运输常规化工运输
样品可协商提供
交期现货/按订单安排

供应说明:雷迪帕韦 常规包装为按订单/批次确认(不公开发布),储存时应密封置于阴凉干燥处,避免与氧化剂混放。济南圣和化工有限公司 支持国内物流发货,大货交期与运费以订单确认为准。

质量与文件

每批产品随货提供 COA(分析证书);可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

作为化工原料供应服务商,济南圣和化工有限公司 长期服务于化工贸易、食品添加、医药中间体、日化原料等行业的采购需求。除 雷迪帕韦 外,您还可以在站内按 CAS 号或产品分类检索更多品类,获取规格与报价。

常见问题

雷迪帕韦 的 CAS 号是多少?

雷迪帕韦 的 CAS 号为 1256388-51-8。

该产品的纯度和包装规格是什么?

常规纯度规格为 按批次COA提供(不公开发布),包装为 按订单/批次确认(不公开发布),随货提供 COA。

雷迪帕韦 有什么用途?

主要应用于有机化学品。

如何购买或获取报价?

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系,注明产品名称、CAS 号与需求数量,一个工作日内回复报价。供应商:济南圣和化工有限公司。

PubChem 公开数据

Description

Ledipasvir · CAS 1256388-51-8 · C49H54F2N8O6. UNII 013TE6E4WV. LogP: 3.8; Dissociation Constants: pka1 = 4.0, pka2 = 5.0.

Identification

CAS Registry Number1256388-51-8
PubChem CID67505836
Molecular formulaC49H54F2N8O6
IUPAC namemethyl N-[(2S)-1-[(6S)-6-[5-[9,9-difluoro-7-[2-[(1R,3S,4S)-2-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]-2-azabicyclo[2.2.1]heptan-3-yl]-3H-benzimidazol-5-yl]fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]heptan-5-yl]-3-methyl-1-oxobutan-2-yl]carbamate
UNII (FDA)013TE6E4WV

Computed Descriptors

Molecular Weight889.0
XLogP37.4
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count10
Rotatable Bond Count12
Exact Mass888.41343780
Monoisotopic Mass888.41343780
Topological Polar Surface Area175
Heavy Atom Count65
Formal Charge0

Physical & Chemical Properties

LogP3.8
Dissociation Constantspka1 = 4.0, pka2 = 5.0

Physical description & handling notes

  • Ledipasvir acts against HCV and is categorized as a direct-acting antiviral agent (DAA). At a dose of 120 mg twice daily (2.67 times the maximum recommended dosage), ledipasvir does not prolong QTc interval to any clinically relevant extent.

Regulatory Status

GHS notification summary50% (1 / 2)

GHS Hazard Classification

GHS notification summary50% (1 / 2)
Reported hazard statementsH371 (50%)

This chemical does not meet GHS hazard criteria for 50% (1 of 2) of reports.

H371 (50%): May cause damage to organs [Warning Specific target organ toxicity, single exposure]

Documented Uses

  • When used in combination with the antiviral medication [sofosbuvir], ledipasvir is indicated for the treatment of treatment of chronic hepatitis C virus (HCV) in adults and pediatric patients 3 years of age and older with the following conditions: - Genotype 1, 4, 5, or 6 infection without cirrhosis or with compensated cirrhosis. - Genotype 1 infection with decompensated cirrhosis, in combination with [ribavirin]. - Genotype 1 or 4 infection who are liver transplant recipients without cirrhosis or with compensated
  • Breast Feeding; Lactation; Milk, Human; Antiviral Agents; NS5A Inhibitors
  • Avoid St. John's Wort. This herb induces PGP and may reduce the serum concentration of ledipasvir.
  • Take separate from antacids. Take at least 4 hours before or after antacids.
  • Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
  • Established Pharmacologic Class [EPC] - Hepatitis C Virus NS5A Inhibitor

Synonyms

Ledipasvir; 1256388-51-8; GS-5885; GS5885; GS 5885; WHO 9796; 013TE6E4WV; CHEBI:85089; DTXSID90154829; HARVONI COMPONENT LEDIPASVIR; ledipasvirum; RefChem:798885; DTXCID8077320; Ledipasvir acetonate; Ledipasvir [USAN:INN]; MFCD25976756

Frequently Asked Questions

What are the CAS number and molecular formula of Ledipasvir?

CAS 1256388-51-8; molecular formula C49H54F2N8O6; molecular weight — g/mol.

What other names is Ledipasvir known by?

Ledipasvir, 1256388-51-8, GS-5885, GS5885, GS 5885, WHO 9796.

Is Ledipasvir classified as hazardous?

50% of GHS notifications report no hazard classification (1 of 2).

What are the key physical properties of Ledipasvir?

LogP: 3.8; Dissociation Constants: pka1 = 4.0, pka2 = 5.0.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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English page: Ledipasvir

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