拉呋替丁

Description

Lafutidine · CAS 118288-08-7 · C22H29N3O4S. UNII 49S4O7ADLC.

Identification

CAS Registry Number	118288-08-7
PubChem CID	5282136
Molecular formula	C22H29N3O4S
IUPAC name	2-(furan-2-ylmethylsulfinyl)-N-[(Z)-4-[[4-(piperidin-1-ylmethyl)-2-pyridinyl]oxy]but-2-enyl]acetamide
UNII (FDA)	49S4O7ADLC

Computed Descriptors

Molecular Weight	431.6
XLogP3	1.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	11
Exact Mass	431.18787759
Monoisotopic Mass	431.18787759
Topological Polar Surface Area	104
Heavy Atom Count	30
Formal Charge	0

GHS Hazard Classification

Reported hazard statements	H302 (100%)

Documented Uses

• Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.
• Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
• A - Alimentary tract and metabolism
• A02 - Drugs for acid related disorders
• A02B - Drugs for peptic ulcer and gastro-oesophageal reflux disease (gord)
• A02BA - H2-receptor antagonists

Synonyms

lafutidine; 118288-08-7; FRG-8813; DTXSID0046434; FRG 8813; Lafutidina; 49S4O7ADLC; DTXCID8026434; N-(4-(4-Piperidinylmethyl)pyridyl-2-oxy)butenyl-2-(furfurylsulfinyl)acetamide; loctidine; lafutidinum; RefChem:798397; A02BA08; 601-513-8; rac Lafutidine; (Z)-Lafutidine

Frequently Asked Questions

What are the CAS number and molecular formula of Lafutidine?

CAS 118288-08-7; molecular formula C22H29N3O4S; molecular weight — g/mol.

What other names is Lafutidine known by?

lafutidine, 118288-08-7, FRG-8813, DTXSID0046434, FRG 8813, Lafutidina.

Is Lafutidine classified as hazardous?

Hazard statements reported: H302.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.